The estimated prevalence of hyperhidrosis ranges from 2% to 16% globally. This may be due to differences in methodology, diagnostic criteria, demographics, or geography.[1]Strutton DR, Kowalski JW, Glaser DA, et al. US prevalence of hyperhidrosis and impact on individuals with axillary hyperhidrosis: results from a national survey. J Am Acad Dermatol. 2004 Aug;51(2):241-8.
http://www.ncbi.nlm.nih.gov/pubmed/15280843?tool=bestpractice.com
[2]Liu Y, Bahar R, Kalia S, et al. Hyperhidrosis prevalence and demographical characteristics in dermatology outpatients in Shanghai and Vancouver. PLoS One. 2016;11(4):e0153719.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153719
http://www.ncbi.nlm.nih.gov/pubmed/27105064?tool=bestpractice.com
[3]Doolittle J, Walker P, Mills T, et al. Hyperhidrosis: an update on prevalence and severity in the United States. Arch Dermatol Res. 2016 Dec;308(10):743-49.
https://link.springer.com/article/10.1007/s00403-016-1697-9
http://www.ncbi.nlm.nih.gov/pubmed/27744497?tool=bestpractice.com
The estimated the prevalence of hyperhidrosis in the US ranges from 2.8% to 4.8%, with approximately half of these people having the axillary variety.[1]Strutton DR, Kowalski JW, Glaser DA, et al. US prevalence of hyperhidrosis and impact on individuals with axillary hyperhidrosis: results from a national survey. J Am Acad Dermatol. 2004 Aug;51(2):241-8.
http://www.ncbi.nlm.nih.gov/pubmed/15280843?tool=bestpractice.com
[3]Doolittle J, Walker P, Mills T, et al. Hyperhidrosis: an update on prevalence and severity in the United States. Arch Dermatol Res. 2016 Dec;308(10):743-49.
https://link.springer.com/article/10.1007/s00403-016-1697-9
http://www.ncbi.nlm.nih.gov/pubmed/27744497?tool=bestpractice.com
One study in Vancouver and Shanghai reported a significantly higher prevalence of axillary hyperhidrosis in white people; there was a higher prevalence of palmar and generalised or facial hyperhidrosis in Southeast Asian people, but the difference was not significant.[2]Liu Y, Bahar R, Kalia S, et al. Hyperhidrosis prevalence and demographical characteristics in dermatology outpatients in Shanghai and Vancouver. PLoS One. 2016;11(4):e0153719.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153719
http://www.ncbi.nlm.nih.gov/pubmed/27105064?tool=bestpractice.com
Approximately 50% of patients with palmar hyperhidrosis have a family history of the disorder.[4]Ro KM, Cantor RM, Lange KL, et al. Palmar hyperhidrosis: evidence of genetic transmission. J Vasc Surg. 2002 Feb;35(2):382-6.
http://www.jvascsurg.org/article/S0741-5214%2802%2994862-7/fulltext
http://www.ncbi.nlm.nih.gov/pubmed/11854739?tool=bestpractice.com
[5]Higashimoto I, Yoshiura K, Hirakawa N, et al. Primary palmar hyperhidrosis locus maps to 14q11.2-q13. Am J Med Genet A. 2006 Mar 15;140(6):567-72.
http://www.ncbi.nlm.nih.gov/pubmed/16470694?tool=bestpractice.com
There is no obvious sex predisposition.[1]Strutton DR, Kowalski JW, Glaser DA, et al. US prevalence of hyperhidrosis and impact on individuals with axillary hyperhidrosis: results from a national survey. J Am Acad Dermatol. 2004 Aug;51(2):241-8.
http://www.ncbi.nlm.nih.gov/pubmed/15280843?tool=bestpractice.com
[6]Shargall Y, Spratt E, Zeldin RA. Hyperhidrosis: what is it and why does it occur? Thorac Surg Clin. 2008 May;18(2):125-32.
http://www.ncbi.nlm.nih.gov/pubmed/18557586?tool=bestpractice.com
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