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Hyperhidrosis

Last reviewed: 4 Apr 2025
Last updated: 18 Jan 2024

Summary

Definition

History and exam

Key diagnostic factors

  • excessive palmar sweating
  • excessive plantar sweating
  • onset in early childhood or puberty
  • exacerbation of palmar sweating with use of hand lotion
  • severe facial sweating
  • severe axillary sweating
  • generalized sweating
Full details

Risk factors

  • family history
  • spicy foods
  • medications
  • endocrine disorders
  • cardiovascular diseases
  • hypoglycemia
  • menopause
  • infectious diseases
  • sepsis
  • neoplastic diseases
  • carcinoid tumors
  • neurologic injuries
  • obesity
Full details

Diagnostic tests

Tests to consider

  • starch-iodine test
  • gravimetry
  • thyroid function test
  • metabolic panel
  • 24-hour urine collection for catecholamines, metanephrines, normetanephrines
  • serum free metanephrines, normetanephrines
  • urine 5-hydroxyindoleacetic acid
  • chest x-ray
  • CT scans
Full details

Treatment algorithm

ACUTE

primary: axillary hyperhidrosis

primary: palmar hyperhidrosis

primary: plantar hyperhidrosis

primary: craniofacial hyperhidrosis

secondary hyperhidrosis

Contributors

Authors

Fritz J. Baumgartner, MD
Fritz J. Baumgartner

Surgery Associates

Long Beach

Clinical Assistant Professor of Surgery

Division of Cardiothoracic Surgery

Harbor-UCLA Medical Center

Torrance

CA

Disclosures

FJB is author of a number of references cited in this topic.

Peer reviewers

Jane S. Bellet, MD

Professor of Pediatrics and Dermatology

Duke University School of Medicine

Durham

NC

Disclosures

JSB declares that he has no competing interests.

Jonathan Villena-Vargas, MD

Assistant Professor of Cardiothoracic Surgery

Cardiothoracic Surgery Department

New York-Presbyterian/Weill Cornell Medical Center

NY

Disclosures

JVV declares that he has no competing interests.

Alan Cameron, MA, MCh, FRCS

Consultant Surgeon

Ipswich Hospital NHS Trust

Ipswich

UK

Disclosures

AC declares that he has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

International Hyperhidrosis Society. Clinical guidelines. 2018 [internet publication].Full text

International Hyperhidrosis Society. Diagnosis guidelines. 2018 [internet publication].Full text

Baumgartner FJ. Surgical approaches and techniques in the management of severe hyperhidrosis. Thorac Surg Clin. 2008 May;18(2):167-81. Abstract

McConaghy JR, Fosselman D. Hyperhidrosis: management options. Am Fam Physician. 2018 Jun 1;97(11):729-34.Full text  Abstract

Cerfolio RJ, De Campos JR, Bryant AS, et al. The Society of Thoracic Surgeons expert consensus for the surgical treatment of hyperhidrosis. Ann Thorac Surg. 2011 May;91(5):1642-8.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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