Summary
Definition
History and exam
Key diagnostic factors
- excessive palmar sweating
- excessive plantar sweating
- onset in early childhood or puberty
- exacerbation of palmar sweating with use of hand lotion
- severe facial sweating
- severe axillary sweating
- generalized sweating
Risk factors
- family history
- spicy foods
- medications
- endocrine disorders
- cardiovascular diseases
- hypoglycemia
- menopause
- infectious diseases
- sepsis
- neoplastic diseases
- carcinoid tumors
- neurologic injuries
- obesity
Diagnostic tests
Tests to consider
- starch-iodine test
- gravimetry
- thyroid function test
- metabolic panel
- 24-hour urine collection for catecholamines, metanephrines, normetanephrines
- serum free metanephrines, normetanephrines
- urine 5-hydroxyindoleacetic acid
- chest x-ray
- CT scans
Treatment algorithm
primary: axillary hyperhidrosis
primary: palmar hyperhidrosis
primary: plantar hyperhidrosis
primary: craniofacial hyperhidrosis
secondary hyperhidrosis
Contributors
Authors
Fritz J. Baumgartner, MD

Surgery Associates
Long Beach
Clinical Assistant Professor of Surgery
Division of Cardiothoracic Surgery
Harbor-UCLA Medical Center
Torrance
CA
Disclosures
FJB is author of a number of references cited in this topic.
Peer reviewers
Jane S. Bellet, MD
Professor of Pediatrics and Dermatology
Duke University School of Medicine
Durham
NC
Disclosures
JSB declares that he has no competing interests.
Jonathan Villena-Vargas, MD
Assistant Professor of Cardiothoracic Surgery
Cardiothoracic Surgery Department
New York-Presbyterian/Weill Cornell Medical Center
NY
Disclosures
JVV declares that he has no competing interests.
Alan Cameron, MA, MCh, FRCS
Consultant Surgeon
Ipswich Hospital NHS Trust
Ipswich
UK
Disclosures
AC declares that he has no competing interests.
References
Key articles
International Hyperhidrosis Society. Clinical guidelines. 2018 [internet publication].Full text
International Hyperhidrosis Society. Diagnosis guidelines. 2018 [internet publication].Full text
Baumgartner FJ. Surgical approaches and techniques in the management of severe hyperhidrosis. Thorac Surg Clin. 2008 May;18(2):167-81. Abstract
McConaghy JR, Fosselman D. Hyperhidrosis: management options. Am Fam Physician. 2018 Jun 1;97(11):729-34.Full text Abstract
Cerfolio RJ, De Campos JR, Bryant AS, et al. The Society of Thoracic Surgeons expert consensus for the surgical treatment of hyperhidrosis. Ann Thorac Surg. 2011 May;91(5):1642-8.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Guidelines
- About hyperhidrosis: diagnosis guidelines
- About hyperhidrosis: clinical guidelines
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