Epidemiology
The primary form is the most common (present in up to 70% of the world's population, although not all demonstrate the symptoms of lactose intolerance),[1]Matthews SB, Waud JP, Roberts AG, et al. Systemic lactose intolerance: a new perspective on an old problem. Postgrad Med J. 2005 Mar;81(953):167-73.
https://pmj.bmj.com/content/81/953/167.long
http://www.ncbi.nlm.nih.gov/pubmed/15749792?tool=bestpractice.com
[4]Kretchmer N. Lactose and lactase - a historical perspective. Gastroenterology. 1971 Dec;61(6):805-13.
http://www.ncbi.nlm.nih.gov/pubmed/4947662?tool=bestpractice.com
[5]Kretchmer N. On the homology between human development and pediatrics. Pediatr Res. 1968 Jul;2(4):283-6.
http://www.ncbi.nlm.nih.gov/pubmed/5669665?tool=bestpractice.com
[6]Cavalli-Sforza LL. Analytic review: some current problems of human population genetics. Am J Hum Genet. 1973 Jan;25(1):82-104.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1762215/pdf/ajhg00446-0084.pdf
http://www.ncbi.nlm.nih.gov/pubmed/4567614?tool=bestpractice.com
[7]Hertzler SR, Savaiano DA. Colonic adaptation to daily lactose feeding in lactose maldigesters reduces lactose intolerance. Am J Clin Nutr. 1996 Aug;64(2):232-6.
http://www.ncbi.nlm.nih.gov/pubmed/8694025?tool=bestpractice.com
while congenital disease is extremely rare (with approximately 40 cases reported worldwide to date).[3]Lomer ME, Parkes GC, Sanderson JD. Lactose intolerance in clinical practice - myths and realities. Aliment Pharmacol Ther. 2008 Jan 15;27(2):93-103.
http://www.ncbi.nlm.nih.gov/pubmed/17956597?tool=bestpractice.com
[8]Swallow DM. Genetics of lactase persistence and lactose intolerance. Annu Rev Genet. 2003;37:197-219.
http://www.ncbi.nlm.nih.gov/pubmed/14616060?tool=bestpractice.com
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