The general prevalence of enuresis at age 5 years is between 5% and 10%.[1][2] It is more common in boys, with a 2:1 male to female ratio reported.[5][6] The natural history of urine control is that most children are dry during the day before they are dry at night. The average age of toilet training has been rising for the last 50 years. In a prospective cohort study, median age of dryness during the day was 3.5 years, and median age of dryness at night was 4 years.[7] Longitudinal studies have shown an annual resolution rate of enuresis of approximately 15% without any intervention.[8]

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