Epidemiology

A review of the intussusception literature suggests a mean incidence of 74 per 100,000 among children <1 year of age, with peak incidence among infants 5-7 months of age.[8] In the US, intussusception occurs in 18 to 56 per 100,000 infants, most commonly in infants aged between 5 and 7 months.[9] Boys are more commonly affected than girls.[5][9][10][11][12][13] Up to 75% of cases occur in children under the age of 12 months.[10][13]In Chile, an incidence of 32 to 35 per 100,000 infants has been reported with an incidence of 47 to 55 per 100,000 per year in infants aged under 1 year. [10]The incidence in Hong Kong is reported at 89 to 101 per 100,000 (1997 to 1999).[14] In a prospective study (261 infants with intussusception) in the UK and Ireland, the peak incidence was between the ages of 5 to 9 months.[15]Incidence data derived from studies that exclude children ≥12 months of age may be subject to bias.[15][8]

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