Approach

Jaundice is usually noted by yellow discoloration of the skin and sclera with the naked eye.[34][35][36][37] However, visual estimation of the degree of jaundice can lead to errors, particularly in darkly pigmented neonates. Therefore, every jaundiced neonate should have a transcutaneous bilirubin measurement. Jaundice is physiological if it happens in postnatal day 2 and resolves by a week of life and transcutaneous measurement is normal. All neonates with jaundice in the first 24 hours of life and those with increased transcutaneous bilirubin after 24 hours of life need further evaluation.

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