About 15% of the white population has a RhD-negative blood type.[4] Population data suggest that the incidence of RhD negativity is highest among Basques (36%).[4] Seven percent of black people have this blood type.[4] Less than 1% of the Native American and Asian populations have this phenotype.[4] Rh alloimmunisation due to RhD has declined markedly as immunoprophylaxis has become routine practice in the last 4 decades.[5][6] Societal factors, such as delayed childbearing and smaller families, may also have contributed to this decline.[5]

BMJ Best Practice is an evidence-based point of care tool for healthcare practitioners.

To continue reading and access all of BMJ Best Practice's pages you'll need to log in or start a free trial.

You can access through your institution if your hospital, university, trust or other institution provides access to BMJ Best Practice through either OpenAthens or Shibboleth.

Use of this content is subject to our disclaimer