Approach

RMSF is a notifiable disease. Clinicians should prescribe antibiotic therapy (doxycycline) once the diagnosis is reasonably considered, without waiting for results of confirmatory tests. Early consideration of the diagnosis and initiation of therapy is important as the case fatality rate increases considerably after 5 days of illness. This presents a challenge, as no constellation of signs and symptoms definitely confirms or excludes the diagnosis, and fever with headache is a common presentation of many illnesses.

BMJ Best Practice is an evidence-based point of care tool for healthcare practitioners.

To continue reading and access all of BMJ Best Practice's pages you'll need to log in or start a free trial.

You can access through your institution if your hospital, university, trust or other institution provides access to BMJ Best Practice through either OpenAthens or Shibboleth.

Use of this content is subject to our disclaimer