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Traveler's diarrhea

Last reviewed: 24 Sep 2025
Last updated: 03 Sep 2024

Summary

Definition

History and exam

Key diagnostic factors

  • diarrhea (with or without tenesmus), cramping, nausea, and vomiting
  • dysentery (blood and fever)
  • persistent diarrhea >14 days
Full details

Other diagnostic factors

  • diarrhea without illness
Full details

Risk factors

  • travel to a high-risk destination
  • age <30 years
  • proton-pump inhibitor use
  • travelers with prior residence in higher-risk destination visiting friends and relatives
  • travel during hot and wet seasons
  • deployed military populations
  • lack of caution in food and water selection
Full details

Diagnostic tests

Primeras pruebas diagnósticas para solicitar

  • stool culture and sensitivity
  • multipathogen molecular diagnostic (polymerase chain reaction)
  • protozoal stool antigens
Todos los datos

Pruebas diagnósticas que deben considerarse

  • stool ova and parasite exam
  • Clostridioides difficile stool toxin
  • colonoscopy, endoscopy, and biopsy
  • hematology, blood chemistries, serology
Todos los datos

Algoritmo de tratamiento

Inicial

pretravel prophylaxis

pre-travel prophylaxis

Agudo

nonpregnant adults: mild diarrhea

nonpregnant adults: moderate diarrhea

nonpregnant adults: severe diarrhea

pregnant

children

Colaboradores

Autores

Daniel T. Leung, MD, MSc

Associate Professor

Division of Infectious Diseases

University of Utah School of Medicine

Salt Lake City

UT

Divulgaciones

DTL receives authorship royalties from UpToDate, Inc, for a chapter on travel medicine. DTL is an author of upcoming chapters on traveler's diarrhea for the US CDC Yellow Book. DTL is the president-elect of the American Committee on Clinical Tropical Medicine and Travelers' Health - Clinical Group within the American Society of Tropical Medicine and Hygiene. DTL is an author of some of the references cited in this topic.

Jakrapun Pupaibool, MD, MS

Associate Professor

Division of Infectious Diseases

University of Utah School of Medicine

Salt Lake City

UT

Divulgaciones

JP declares that he has no competing interests.

Agradecimientos

Dr Daniel T. Leung and Dr Jakrapun Pupaibool would like to gratefully acknowledge Dr Mark Riddle and Professor Gregory Juckett, the previous contributor to this topic.

Divulgaciones

MR has given talks on the management of traveler's diarrhea for the International Society of Travel Medicine (ISTM), the CDC Foundation, the American College of Gastroenterology (ACG), and the American College of Preventive Medicine. MR has led the development of guidelines for traveler's diarrhea for the ISTM, the ACG, and the Department of Defense. This work has been unpaid but support for travel has been accepted. MR is employed with Pfizer Inc., and is working on their Lyme disease vaccine program. While this is not in conflict with traveler’s diarrhea, Pfizer also makes azithromycin, which is an antibiotic recommended for the treatment of traveler’s diarrhea. MR does not work in the area of Pfizer that develops, markets, or distributes azithromycin. MR is an author of several references cited in this topic. GJ declares that he has no competing interests.

Revisores por pares

Andrea Summer, MD

Assistant Professor of Pediatrics

Medical University of South Carolina

Charleston

SC

Divulgaciones

AS declares that she has no competing interests.

Phil Fischer, MD

Professor of Pediatrics

Department of Pediatric and Adolescent Medicine

Mayo Clinic

Rochester

MN

Divulgaciones

PF is an author of a reference cited in this topic.

Agradecimiento de los revisores por pares

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Divulgaciones

Las afiliaciones y divulgaciones de los revisores por pares se refieren al momento de la revisión.

Referencias

Nuestros equipos internos de evidencia y editoriales colaboran con colaboradores expertos internacionales y revisores pares para garantizar que brindemos acceso a la información más clínicamente relevante posible.

Artículos principales

Riddle MS, Connor BA, Beeching NJ, et al. Guidelines for the prevention and treatment of travelers' diarrhea: a graded expert panel report. J Travel Med. 2017 Apr 1;24(suppl 1):S57-74.Texto completo  Resumen

Centers for Disease Control and Prevention. CDC Yellow Book 2024: health information for international travel.​ Section 2: preparing international travelers - travelers’ diarrhea. May 2023 [internet publication].Texto completo

De Bruyn G, Hahn S, Borwick A. Antibiotic treatment for travellers' diarrhoea. Cochrane Database Syst Rev. 2000;(3):CD002242.Texto completo  Resumen

Johnson PC, Ericsson CD, DuPont HL, et al. Comparison of loperamide with bismuth subsalicylate for the treatment of acute travelers' diarrhea. JAMA. 1986 Feb 14;255(6):757-60. Resumen

Artículos de referencia

Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
  • Diferenciales

    • Food poisoning
    • Irritable bowel syndrome
    • Secondary disaccharidase (or other dietary) deficiency
    Más Diferenciales
  • Guías de práctica clínica

    • CDC Yellow Book 2024: travelers' diarrhea
    • 2017 Infectious Diseases Society of America clinical practice guidelines for the diagnosis and management of infectious diarrhea​
    Más Guías de práctica clínica
  • Folletos para el paciente

    Diarrhea in adults

    Más Folletos para el paciente
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