Influenza infection

Centers for Disease Control and Prevention. Influenza (flu). Oct 2021 [internet publication].Full text

1. Brankston G, Gitterman L, Hirji Z, et al. Transmission of influenza A in human beings. Lancet Infect Dis. 2007 Apr;7(4):257-65. Abstract

2. Uyeki TM, Bernstein HH, Bradley JS, et al. Clinical practice guidelines by the Infectious Diseases Society of America: 2018 update on diagnosis, treatment, chemoprophylaxis, and institutional outbreak management of seasonal influenza. Clin Infect Dis. 2019 Mar 5;68(6):e1-47.Full text  Abstract

3. Neuzil KM, Wright PF, Mitchel EF Jr, et al. The burden of influenza illness in children with asthma and other chronic medical conditions. J Pediatr. 2000 Dec;137(6):856-64. Abstract

4. Martin CM, Kunin CM, Gottlieb LS, et al. Asian influenza A in Boston, 1957-1958. Arch Intern Med. 1959 Apr;103(4):515-31. Abstract

5. Nicholson K, Wood JM, Zambon M, et al. Influenza. Lancet. 2003 Nov 22;362(9397):1733-45. Abstract

6. Zimmer SM, Burke DS. Historical perspective - Emergence of influenza A (H1N1) viruses. N Engl J Med. 2009 Jul 16;361(3):279-85. Abstract

7. Australian Government Department of Health. Australian Influenza Surveillance Report. No. 12, 2017. Oct 2017 [internet publication].Full text

8. Public Health England. National flu immunisation programme plan. Jul 2021 [internet publication].Full text

9. Uyeki TM, Wentworth DE, Jernigan DB. Influenza activity in the US during the 2020-2021 season. JAMA. 2021 Jun 8;325(22):2247-8.Full text  Abstract

10. Centers for Disease Control and Prevention. Reconstruction of the 1918 influenza pandemic virus. Dec 2019 [internet publication].Full text

11. Stephenson I, Zambon M. The epidemiology of influenza. Occup Med (Lond). 2002 Aug;52(5):241-7. Abstract

12. Klimov A, Rocha E, Hayden FG, et al. Prolonged shedding of amantadine-resistant influenza A viruses by immunodeficient patients: detection by polymerase chain reaction-restriction analysis. J Infect Dis. 1995 Nov;172(5):1352-5. Abstract

13. Centers for Disease Control and Prevention (CDC). Estimates of deaths associated with seasonal influenza - United States, 1976-2007. MMWR Morb Mortal Wkly Rep. 2010 Aug 27;59(33):1057-62.Full text  Abstract

14. Kostova D, Reed C, Finelli L, et al. Influenza illness and hospitalizations averted by influenza vaccination in the United States, 2005-2011. PLoS One. 2013 Jun 19;8(6):e6631.Full text  Abstract

15. Centers for Disease Control and Prevention. Influenza (flu). Oct 2021 [internet publication].Full text

16. Committee on Infectious Diseases. Recommendations for prevention and control of influenza in children, 2021-2022. Pediatrics. 2021 Oct;148(4):.Full text  Abstract

17. Hutchinson AF, Ghimire AK, Thompson MA, et al. A community-based, time-matched, case-control study of respiratory viruses and exacerbations of COPD. Respir Med. 2007 Dec;101(12):2472-81. Abstract

18. Kopsaftis Z, Wood-Baker R, Poole P. Influenza vaccine for chronic obstructive pulmonary disease (COPD). Cochrane Database Syst Rev. 2018 Jun 26;(6):CD002733.Full text  Abstract

19. Bekkat-Berkani R, Wilkinson T, Buchy P, et al. Seasonal influenza vaccination in patients with COPD: a systematic literature review. BMC Pulm Med. 2017 May 3;17(1):79.Full text  Abstract

20. Nichol KL, Nordin J, Mullooly J, et al. Influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderly. N Engl J Med. 2003 Apr 3;348(14):1322-32.Full text  Abstract

21. Dos Santos G, Tahrat H, Bekkat-Berkani R. Immunogenicity, safety, and effectiveness of seasonal influenza vaccination in patients with diabetes mellitus: asystematic review. Hum Vaccin Immunother. 2018;14(8):1853-66.Full text  Abstract

22. Orzeck EA, Shi N, Blumentals WA. Oseltamivir and the risk of influenza-related complications and hospitalizations in patients with diabetes. Clin Ther. 2007 Oct;29(10):2246-55. Abstract

23. Mehta SR, Afenyi-Annan A, Byrns PJ, et al. Opportunities to improve outcomes in sickle cell disease. Am Fam Physician. 2006 Jul 15;74(2):303-10. Abstract

24. Kim YJ, Boeckh M, Englund JA. Community respiratory virus infections in immunocompromised patients: hematopoietic stem cell and solid organ transplant recipients, and individuals with human immunodeficiency virus infection. Semin Respir Crit Care Med. 2007 Apr;28(2):222-42. Abstract

25. Zhang W, Sun H, Atiquzzaman M, et al. Influenza vaccination for HIV-positive people: systematic review and network meta-analysis. Vaccine. 2018 Jun 27;36(28):4077-86. Abstract

26. Danziger-Isakov L, Kumar D, AST ID Community of Practice. Vaccination of solid organ transplant candidates and recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice. Clin Transplant. 2019 Sep;33(9):e13563. Abstract

27. Beck CR, McKenzie BC, Hashim AB, et al. Influenza vaccination for immunocompromised patients: systematic review and meta-analysis from a public health policy perspective. PLoS One. 2011 Dec 22;6(12):e29249.Full text  Abstract

28. McKittrick N, Frank I, Jacobson JM, et al. Improved immunogenicity with high-dose seasonal influenza vaccine in HIV-infected persons: a single-center, parallel, randomized trial. Ann Intern Med. 2013 Jan 1;158(1):19-26. Abstract

29. Madhi SA, Cutland CL, Kuwanda L, et al.; Maternal Flu Trial (Matflu) Team. Influenza vaccination of pregnant women and protection of their infants. N Engl J Med. 2005 Oct 21;54(41):1050-2.Full text  Abstract

30. Kumar D, Campbell P, Hoschler K, et al. Randomized controlled trial of adjuvanted versus nonadjuvanted influenza vaccine in kidney transplant recipients. Transplantation. 2016 Mar;100(3):662-9. Abstract

31. Grohskopf LA, Alyanak E, Ferdinands JM, et al. Prevention and control of seasonal influenza with vaccines: recommendations of the advisory committee on immunization practices, United States, 2021-22 influenza season. MMWR Recomm Rep. 2021 Aug 27;70(5):1-28.Full text  Abstract

32. Hak E, Nordin J, Wei F, et al. Influence of high-risk medical conditions on the effectiveness of influenza vaccination among elderly members of 3 large managed-care organizations. Clin Infect Dis. 2002 Aug 15;35(4):370-7. Abstract

33. Centers for Disease Control and Prevention. Recommendations for obstetric health care providers related to use of antiviral medications in the treatment and prevention of influenza. Nov 2020 [internet publication].Full text

34. American College of Obstetricians and Gynecologists. Assessment and treatment of pregnant women with suspected or confirmed influenza: ACOG Committee Opinion No. 753. Obstet Gynecol. 2018 Oct;132(4):e169-73.Full text  Abstract

35. Nunes MC, Aqil AR, Omer SB, Madhi SA. The effects of influenza vaccination during pregnancy on birth outcomes: a systematic review and meta-analysis. Am J Perinatol. 2016 Sep;33(11):1104-14.Full text  Abstract

36. American College of Obstetricians and Gynecologists. Influenza vaccination during pregnancy: ACOG Committee Opinion No. 732. Obstet Gynecol. 2018 Apr;131(4):e109-14.Full text  Abstract

37. Polyzos KA, Konstantelias AA, Pitsa CE, et al. Maternal influenza vaccination and risk for congenital malformations: a systematic review and meta-analysis. Obstet Gynecol. 2015 Nov;126(5):1075-84. Abstract

38. Advisory Committee on Immunization Practices; Centers for Disease Control and Prevention (CDC). Immunization of health-care personnel: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011 Nov 25;60(RR-7):1-45.Full text  Abstract

39. Bernstein HH, Starke JR; American Academy of Pediatrics; et al. Policy statement - recommendation for mandatory influenza immunization of all health care personnel. Pediatrics. 2010 Oct;126(4):809-15. Abstract

40. Centers for Disease Control and Prevention. Frequently asked influenza (flu) questions: 2021-2022 season. Oct 2021 (internet publication].Full text

41. Jackson LA, Gaglani MJ, Keyserling HL, et al. Safety, efficacy, and immunogenicity of an inactivated influenza vaccine in healthy adults: a randomized, placebo-controlled trial over two influenza seasons. BMC Infect Dis. 2010 Mar 17;10:71. Abstract

42. Beyer WE, Nauta JJ, Palache AM, et al. Immunogenicity and safety of inactivated influenza vaccines in primed populations: a systematic literature review and meta-analysis. Vaccine. 2011 Aug 5;29(34):5785-92. Abstract

43. Demicheli V, Jefferson T, Ferroni E, et al. Vaccines for preventing influenza in healthy adults. Cochrane Database Syst Rev. 2018 Feb 1;(2):CD001269.Full text  Abstract

44. Bitterman R, Eliakim-Raz N, Vinograd I, et al. Influenza vaccines in immunosuppressed adults with cancer. Cochrane Database Syst Rev. 2018 Feb 1;(2):CD008983.Full text  Abstract

45. Jefferson T, Rivetti A, Di Pietrantonj C, et al. Vaccines for preventing influenza in healthy children. Cochrane Database Syst Rev. 2018 Feb 1;(2):CD004879.Full text  Abstract

46. Demicheli V, Jefferson T, Di Pietrantonj C, et al. Vaccines for preventing influenza in the elderly. Cochrane Database Syst Rev. 2018 Feb 1;(2):CD004876.Full text  Abstract

47. Rondy M, El Omeiri N, Thompson MG, et al. Effectiveness of influenza vaccines in preventing severe influenza illness among adults: a systematic review and meta-analysis of test-negative design case-control studies. J Infect. 2017 Nov;75(5):381-94.Full text  Abstract

48. Vasileiou E, Sheikh A, Butler C, et al. Effectiveness of influenza vaccines in asthma: a systematic review and meta-analysis. Clin Infect Dis. 2017 Oct 15;65(8):1388-95.Full text  Abstract

49. Public Health England. National flu immunisation programme plan. Dec 2020 [internet publication].Full text

50. Englund JA, Walter E, Black S, et al. Safety and immunogenicity of trivalent inactivated influenza vaccine in infants: a randomized double-blind placebo-controlled study. Pediatr Infect Dis J. 2010 Feb;29(2):105-10. Abstract

51. Sukumaran L, McCarthy NL, Kharbanda EO, et al. Infant hospitalizations and mortality after maternal vaccination. Pediatrics. 2018 Mar;141(3):e20173310.Full text  Abstract

52. Thompson MG, Kwong JC, Regan AK, et al; PREVENT Workgroup. Influenza vaccine effectiveness in preventing influenza-associated hospitalizations during pregnancy: a multi-country retrospective test negative design study, 2010-2016. Clin Infect Dis. 2019 Apr 24;68(9):1444-53.Full text  Abstract

53. Nunes MC, Madhi SA. Influenza vaccination during pregnancy for prevention of influenza confirmed illness in the infants: a systematic review and meta-analysis. Hum Vaccin Immunother. 2017 Mar 4;14(3):758-66.Full text  Abstract

54. Greenhawt M, Turner PJ, Kelso JM. Administration of influenza vaccines to egg allergic recipients: a practice parameter update 2017. Ann Allergy Asthma Immunol. 2018 Jan;120(1):49-52.Full text  Abstract

55. Centers for Disease Control and Prevention, Advisory Committee on Immunization Practices. Recommended child and adolescent immunization schedule for ages 18 years or younger, United States, 2022. Feb 2022 [internet publication].Full text

56. Centers for Disease Control and Prevention, Advisory Committee on Immunization Practices. Recommended adult immunization schedule for ages 19 years or older, United States, 2022. Feb 2022. [internet publication].Full text

57. Fukuda K, Kieny MP. Different approaches to influenza vaccination. N Engl J Med. 2006 Dec 14;355(24):2586-7.Full text  Abstract

58. Wilde JA, McMillan JA, Serwint J, et al. Effectiveness of influenza vaccine in health care professionals: a randomized trial. JAMA. 1999 Mar 10;281(10):908-13.Full text  Abstract

59. Bridges CB, Thompson WW, Meltzer MI, et al. Effectiveness and cost-benefit of influenza vaccination of healthy working adults: a randomized controlled trial. JAMA. 2000 Oct 4;284(13):1655-63.Full text  Abstract

60. Edwards KM, Dupont WD, Westrich MK, et al. A randomized controlled trial of cold-adapted and inactivated vaccines for the prevention of influenza A disease. J Infect Dis. 1994 Jan;169(1):68-76. Abstract

61. Ohmit SE, Victor JC, Rotthoff JR, et al. Prevention of antigenically drifted influenza by inactivated and live attenuated vaccines. N Engl J Med. 2006 Dec 14;355(24):2513-22.Full text  Abstract

62. DiazGranados CA, Denis M, Plotkin S. Seasonal influenza vaccine efficacy and its determinants in children and non-elderly adults: a systematic review with meta-analyses of controlled trials. Vaccine. 2012 Dec 17;31(1):49-57. Abstract

63. Manzoli L, Ioannidis JP, Flacco ME, et al. Effectiveness and harms of seasonal and pandemic influenza vaccines in children, adults and elderly: a critical review and re-analysis of 15 meta-analyses. Hum Vaccin Immunother. 2012 Jul;8(7):851-62.Full text  Abstract

64. Osterholm MT, Kelley NS, Sommer A, et al. Efficacy and effectiveness of influenza vaccines: a systematic review and meta-analysis. Lancet Infect Dis. 2012 Jan;12(1):36-44. Abstract

65. Monto AS, Rotthoff J, Teich E, et al. Detection and control of outbreaks in well-vaccinated nursing home populations. Clin Infect Dis. 2004 Aug 15;39(4):459-64. Abstract

66. Nichol KL, Nordin JD, Nelson DB, et al. Effectiveness of influenza vaccine in the community-dwelling elderly. N Engl J Med. 2007 Oct 4;357(14):1373-81.Full text  Abstract

67. De Villiers PJ, Steele AD, Hiemstra LA, et al. Efficacy and safety of a live attenuated influenza vaccine in adults 60 years of age and older. Vaccine. 2009 Dec 10;28(1):228-34. Abstract

68. Jefferson T, Rivetti D, Rivetti A, et al. Efficacy and effectiveness of influenza vaccines in elderly people: a systematic review. Lancet. 2005 Oct 1;366(9492):1165-74. Abstract

69. Armstrong BG, Mangtani P, Fletcher A, et al. Effect of influenza vaccination on excess deaths occurring during periods of high circulation of influenza: cohort study in elderly people. BMJ. 2004 Sep 18;329(7467):660.Full text  Abstract

70. Cools HJ, Gussekloo J, Remmerswaal JE, et al. Benefits of increasing the dose of influenza vaccine in residents of long-term care facilities: a randomized placebo-controlled trial. J Med Virol. 2009 May;81(5):908-14. Abstract

71. DiazGranados CA, Dunning AJ, Kimmel M, et al. Efficacy of high-dose versus standard-dose influenza vaccine in older adults. N Engl J Med. 2014 Aug 14;371(7):635-45.Full text  Abstract

72. Nace DA, Lin CJ, Ross TM, et al. Randomized, controlled trial of high-dose influenza vaccine among frail residents of long-term care facilities. J Infect Dis. 2015 Jun 15;211(12):1915-24.Full text  Abstract

73. Lee JKH, Lam GKL, Shin T, et al. Efficacy and effectiveness of high-dose versus standard-dose influenza vaccination for older adults: a systematic review and meta-analysis. Expert Rev Vaccines. 2018 May 16;17(5):435-43. Abstract

74. Samson SI, Leventhal PS, Salamand C, et al. Immunogenicity of high-dose trivalent inactivated influenza vaccine: a systematic review and meta-analysis. Expert Rev Vaccines. 2019 Feb 13;18(3):295-308. Abstract

75. Lehmann HC, Hartung HP, Kieseier BC, et al. Guillain-Barré syndrome after exposure to influenza virus. Lancet Infect Dis. 2010 Sep;10(9):643-51. Abstract

76. Lasky T, Terracciano GJ, Magder L, et al. The Guillain-Barré syndrome and the 1992-1993 and 1993-1994 influenza vaccines. N Engl J Med. 1998 Dec 17;339(25):1797-802. Abstract

77. Centers for Disease Control and Prevention. Influenza signs and symptoms and the role of laboratory diagnostics. Aug 2020 [internet publication].Full text

78. Call SA, Vollenweider MA, Hornung CA, et al. Does this patient have influenza? JAMA. 2005 Feb 23;293(8):987-97. Abstract

79. Hayden FG, Fritz R, Lobo MC, et al. Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense. J Clin Invest. 1998 Feb 1;101(3):643-9.Full text  Abstract

80. Monto AS, Gravenstein S, Elliott M, et al. Clinical signs and symptoms predicting influenza infection. Arch Intern Med. 2000 Nov 27;160(21):3243-7.Full text  Abstract

81. Nicholson KG, Kent J, Hammersley V, et al. Acute viral infections of upper respiratory tract in elderly people living in the community: comparative, prospective, population based study of disease burden. BMJ. 1997 Oct 25;315(7115):1060-4.Full text  Abstract

82. Vesikari T, Beran J, Durviaux S, et al. Use of real-time polymerase chain reaction (rtPCR) as a diagnostic tool for influenza infection in a vaccine efficacy trial. J Clin Virol. 2012 Jan;53(1):22-8. Abstract

83. Egilmezer E, Walker GJ, Bakthavathsalam P, et al. Systematic review of the impact of point-of-care testing for influenza on the outcomes of patients with acute respiratory tract infection. Rev Med Virol. 2018 Sep;28(5):e1995. Abstract

84. Huang HS, Tsai CL, Chang J, et al. Multiplex PCR system for the rapid diagnosis of respiratory virus infection: systematic review and meta-analysis. Clin Microbiol Infect. 2017 Oct;24(10):1055-63.Full text  Abstract

85. Glezen WP, Taber LH, Frank AL, et al. Influenza virus infections in infants. Pediatr Infect Dis J. 1997 Nov;16(11):1065-8. Abstract

86. Peltola V, Ziegler T, Ruuskanen O. Influenza A and B virus infections in children. Clin Infect Dis. 2003 Feb 1;36(3):299-305. Abstract

87. Glezen WP. Influenza viruses. In: Feigin RD, Cherry JD, Demmler GJ, et al., eds. Textbook of pediatric infectious diseases. 5th ed. Philadelphia, PA: WB Saunders; 2004:2252-69.

88. Govaert TM, Dinant GJ, Aretz K, et al. The predictive value of influenza symptomatology in elderly people. Fam Pract. 1998 Feb;15(1):16-22.Full text  Abstract

89. Walsh EE, Cox C, Falsey AR. Clinical features of influenza A virus infection in older hospitalized persons. J Am Geriatr Soc. 2002 Sep;50(9):1498-503. Abstract

90. Neuzil KM, O'Connor TZ, Gorse GJ, et al. Recognizing influenza in older patients with chronic obstructive pulmonary disease who have received influenza vaccine. Clin Infect Dis. 2003 Jan 15;36(2):169-74.Full text  Abstract

91. Ohmit SE, Monto AS. Symptomatic predictors of influenza virus positivity in children during the influenza season. Clin Infect Dis. 2006 Sep 1;43(5):564-8.Full text  Abstract

92. Simonsen L. The global impact of influenza on morbidity and mortality. Vaccine. 1999;17(suppl 1):S3-10. Abstract

93. Lang S, Kansy B. Cervical lymph node diseases in children. GMS Curr Top Otorhinolaryngol Head Neck Surg. 2014;13:Doc08.Full text  Abstract

94. Miller JM, Binnicker MJ, Campbell S, et al. A guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2018 update by the Infectious Diseases Society of America and the American Society for Microbiology. Clin Infect Dis. 2018 Aug 31;67(6):e1-94.Full text  Abstract

95. Merckx J, Wali R, Schiller I, et al. Diagnostic accuracy of novel and traditional rapid tests for influenza infection compared with reverse transcriptase polymerase chain reaction: a systematic review and meta-analysis. Ann Intern Med. 2017 Sep 19;167(6):394-409. Abstract

96. Bruning AHL, Leeflang MMG, Vos JMBW, et al. Rapid tests for influenza, respiratory syncytial virus, and other respiratory viruses: a systematic review and meta-analysis. Clin Infect Dis. 2017 Sep 15;65(6):1026-32.Full text  Abstract

97. Petrozzino JJ, Smith C, Atkinson MJ. Rapid diagnostic testing for seasonal influenza: an evidence-based review and comparison with unaided clinical diagnosis. J Emerg Med. 2010 Oct;39(4):476-90. Abstract

98. Marrie TJ. Community-acquired pneumonia. Clin Infect Dis. 1994 Apr;18(4):501-13. Abstract

99. Solomon DA, Sherman AC, Kanjilal S. Influenza in the COVID-19 era. JAMA. 2020 Oct 6;324(13):1342-3.Full text  Abstract

100. Shay DK, Holman RC, Newman RD, et al. Bronchiolitis-associated hospitalizations among US children, 1980-1996. JAMA. 1999 Oct 20;282(15):1440-6.Full text  Abstract

101. Wald TG, Miller BA, Shult P, et al. Can respiratory syncytial virus and influenza A be distinguished clinically in institutionalized older persons? J Am Geriatr Soc. 1995 Feb;43(2):170-4. Abstract

102. Rose EB, Wheatley A, Langley G, et al. Respiratory syncytial virus seasonality - United States, 2014-2017. MMWR Morb Mortal Wkly Rep. 2018 Jan 19;67(2):71-6.Full text  Abstract

103. Hall CB. Respiratory syncytial virus and parainfluenza virus. N Engl J Med. 2001 Jun 21;344(25):1917-28. Abstract

104. Wendt CH, Hertz MI. Respiratory syncytial virus and parainfluenza virus infections in the immunocompromised host. Semin Respir Infect. 1995 Dec;10(4):224-31. Abstract

105. Denny FW, Clyde WA Jr. Acute lower respiratory tract infections in nonhospitalized children. J Pediatr. 1986 May;108(5 Pt 1):635-46. Abstract

106. Frank AL, Couch RB, Griffis CA, et al. Comparison of different tissue cultures for isolation and quantitation of influenza and parainfluenza viruses. J Clin Microbiol. 1979 Jul;10(1):32-6. Abstract

107. Ray CG, Minnich LL. Efficiency of immunofluorescence for rapid detection of common respiratory viruses. J Clin Microbiol. 1987 Feb;25(2):355-7. Abstract

108. Osiowy C. Direct detection of respiratory syncytial virus, parainfluenza virus, and adenovirus in clinical respiratory specimens by a multiplex reverse transcription-PCR assay. J Clin Microbiol. 1998 Nov;36(11):3149-54. Abstract

109. Fiore AE, Fry A, Shay D, et al. Antiviral agents for the treatment and chemoprophylaxis of influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2011 Jan 21;60(1):1-24.Full text  Abstract

110. National Institute for Health and Care Excellence. Oseltamivir, amantadine (review) and zanamivir for the prophylaxis of influenza. Sep 2008 [internet publication].Full text

111. Cox NJ, Fukuda K. Influenza. Infect Dis Clin North Am. 1998 Mar;12(1):27-38. Abstract

112. Centers for Disease Control and Prevention. Influenza antiviral medications: summary for clinicians. Feb 2022 [internet publication].Full text

113. Public Health England. Influenza: treatment and prophylaxis using anti-viral agents. Oct 2019 [internet publication].Full text

114. Jefferson T, Jones M, Doshi P, et al. Neuraminidase inhibitors for preventing and treating influenza in healthy adults: systematic review and meta-analysis. BMJ. 2009 Dec 8;339:b5106.Full text  Abstract

115. Shun-Shin M, Thompson M, Heneghan C, et al. Neuraminidase inhibitors for treatment and prophylaxis of influenza in children: systematic review and meta-analysis of randomised controlled trials. BMJ. 2009 Aug 10;339:b3172.Full text  Abstract

116. Doll MK, Winters N, Boikos C, et al. Safety and effectiveness of neuraminidase inhibitors for influenza treatment, prophylaxis, and outbreak control: a systematic review of systematic reviews and/or meta-analyses. J Antimicrob Chemother. 2017 Nov 1;72(11):2990-3007. Abstract

117. Venkatesan S, Myles PR, Leonardi-Bee J, et al. Impact of outpatient neuraminidase inhibitor treatment in patients infected with influenza A(H1N1)pdm09 at high risk of hospitalization: an individual participant data metaanalysis. Clin Infect Dis. 2017 May 15;64(10):1328-34. Abstract

118. Jackson RJ, Cooper KL, Tappenden P, et al. Oseltamivir, zanamivir and amantadine in the prevention of influenza: a systematic review. J Infect. 2011 Jan;62(1):14-25. Abstract

119. Jefferson T, Jones MA, Doshi P, et al. Neuraminidase inhibitors for preventing and treating influenza in healthy adults and children. Cochrane Database Syst Rev. 2014;(4):CD008965.Full text  Abstract

120. Heneghan CJ, Onakpoya I, Thompson M, et al. Zanamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments. BMJ. 2014 Apr 9;348:g2547.Full text  Abstract

121. Jefferson T, Jones M, Doshi P, et al. Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments. BMJ. 2014 Apr 9;348:g2545.Full text  Abstract

122. Cohen D. Complications: tracking down the data on oseltamivir. BMJ. 2009 Dec 8;339:b5387. Abstract

123. Doshi P. Neuraminidase inhibitors - the story behind the Cochrane review. BMJ. 2009 Dec 8;339:b5164. Abstract

124. Jefferson T, Doshi P, Thompson M, et al. Ensuring safe and effective drugs: who can do what it takes? BMJ. 2011 Jan 11;342:c7258. Abstract

125. Dobson J, Whitley RJ, Pocock S, et al. Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials. Lancet. 2015 May 2;385(9979):1729-37. Abstract

126. Uyeki T. Antiviral treatment for patients hospitalized with 2009 pandemic influenza A (H1N1). N Engl J Med. 2009 Dec 3;361(23):e110. Abstract

127. Wang K, Shun-Shin M, Gill P, et al. Neuraminidase inhibitors for preventing and treating influenza in children (published trials only). Cochrane Database Syst Rev. 2012 Apr 18;(1):CD002744.Full text  Abstract

128. Stiver G. The treatment of influenza with antiviral drugs. CMAJ. 2003 Jan 7;168(1):49-56.Full text  Abstract

129. Heinonen S, Silvennoinen H, Lehtinen P, et al. Early oseltamivir treatment of influenza in children 1-3 years of age: a randomized controlled trial. Clin Infect Dis. 2010 Oct 15;51(8):887-94. Abstract

130. Ikematsu H, Hayden FG, Kawaguchi K, et al. Baloxavir marboxil for prophylaxis against influenza in household contacts. N Engl J Med. 2020 Jul 23;383(4):309-20.Full text  Abstract

131. US Food and Drug Administration. FDA Drug Safety Communication: FDA updates warnings for oral and injectable fluoroquinolone antibiotics due to disabling side effects. Jul 2016 [internet publication].Full text

132. European Medicines Agency. Quinolone- and fluoroquinolone-containing medicinal products. Mar 2019 [internet publication].Full text

133. US Food and Drug Administration. FDA reinforces safety information about serious low blood sugar levels and mental health side effects with fluoroquinolone antibiotics; requires label changes. Jul 2018 [internet publication].Full text

134. US Food and Drug Administration. FDA warns about increased risk of ruptures or tears in the aorta blood vessel with fluoroquinolone antibiotics in certain patients. Dec 2018 [internet publication].Full text

135. Dowell SF, Butler JC, Giebink GS, et al. Acute otitis media: management and surveillance in an era of pneumococcal resistance - a report from the Drug-resistant Streptococcus Pneumoniae Therapeutic Working Group. Pediatr Infect Dis J. 1999 Jan;18(1):1-9. Abstract

136. Lieberthal AS, Carroll AE, Chonmaitree T, et al. The diagnosis and management of acute otitis media. Pediatrics. 2013 Feb 25;131(3):e964-99.Full text  Abstract

137. McAllister L, Anderson J, Werth K, et al. Needle-free jet injection for administration of influenza vaccine: a randomised non-inferiority trial. Lancet. 2014 Aug 23;384(9944):674-81. Abstract

138. Moscona A. Medical management of influenza infection. Annu Rev Med. 2008 Feb;59:397-413. Abstract

139. Ilyushina NA, Hoffmann E, Salomon R, et al. Amantadine-oseltamivir combination therapy for H5N1 influenza virus infection in mice. Antivir Ther. 2007;12(3):363-70. Abstract

140. Smee DF, Hurst BL, Wong MH, et al. Effects of the combination of favipiravir (T-705) and oseltamivir on influenza A virus infections in mice. Antimicrob Agents Chemother. 2010 Jan;54(1):126-33.Full text  Abstract

141. Ilyushina NA, Bovin NV, Webster RG, et al. Combination chemotherapy, a potential strategy for reducing the emergence of drug-resistant influenza A variants. Antiviral Res. 2006 Jul;70(3):121-31. Abstract

142. Duval X, van der Werf S, Blanchon T, et al. Efficacy of oseltamivir-zanamivir combination compared to each monotherapy for seasonal influenza: a randomized placebo-controlled trial. PLoS Med. 2010 Nov 2;7(11):e1000362.Full text  Abstract

143. Belser JA, Lu X, Szretter KJ, et al. DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection. J Infect Dis. 2007 Oct 31;196(10):1493-9.Full text  Abstract

144. Moscona A, Porotto M, Palmer S, et al. A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo. J Infect Dis. 2010 Jul 15;202(2):234-41.Full text  Abstract

145. Wu C, Chen W, Chen J, H. Preparation of monoPEGylated Cyanovirin-N's derivative and its anti-influenza A virus bioactivity in vitro and in vivo. J Biochem. 2015 Jun;157(6):539-48. Abstract

146. Švančarová P, Svetlíková D, Betáková T. Induction of interferon lambda in influenza A virus infected cells treated with shRNAs against M1 transcript. Acta Virol. 2015 Jun;59(2):148-55. Abstract

147. Furuta Y, Gowen BB, Takahashi K, et al. Favipiravir (T-705), a novel viral RNA polymerase inhibitor. Antiviral Res. 2013 Nov;100(2):446-54.Full text  Abstract

148. Beigel J, Bray M. Current and future antiviral therapy of severe seasonal and avian influenza. Antiviral Res. 2008 Apr;78(1):91-102.Full text  Abstract

149. Jones S, Evans K, McElwaine-Johnn H, et al. DNA vaccination protects against an influenza challenge in a double-blind randomised placebo-controlled phase 1b clinical trial. Vaccine. 2009 Apr 21;27(18):2506-12. Abstract

150. Smith LR, Wloch MK, Ye M, et al. Phase 1 clinical trials of the safety and immunogenicity of adjuvanted plasmid DNA vaccines encoding influenza A virus H5 hemagglutinin. Vaccine. 2010 Mar 16;28(13):2565-72. Abstract

151. GBD 2017 Influenza Collaborators. Mortality, morbidity, and hospitalisations due to influenza lower respiratory tract infections, 2017: an analysis for the Global Burden of Disease Study 2017. Lancet Respir Med. 2018 Dec 12;7(1):69-89.Full text  Abstract

152. Schwarzmann SW, Adler JL, Sullivan RJ Jr, et al. Bacterial pneumonia during the Hong Kong influenza epidemic of 1968-1969. Arch Intern Med. 1971 Jun;127(6):1037-41. Abstract

153. Newland JG, Laurich VM, Rosenquist AW, et al. Neurologic complications in children hospitalized with influenza: characteristics, incidence, and risk factors. J Pediatr. 2007 Mar;150(3):306-10. Abstract

154. Winther B, Block SL, Reisinger K, et al. Impact of oseltamivir treatment on the incidence and course of acute otitis media in children with influenza. Int J Pediatr Otorhinolaryngol. 2010 Jun;74(6):684-8. Abstract

155. Casey JR, Pichichero ME. Changes in frequency and pathogens causing acute otitis media in 1995-2003. Pediatr Infect Dis J. 2004 Sep;23(9):824-8. Abstract

156. Gamboa ET, Eastwood AB, Hays AP, et al. Isolation of influenza virus from muscle in myoglobinuric polymyositis. Neurology. 1979 Oct;29(10):1323-35. Abstract

157. Dell KM, Schulman SL. Rhabdomyolysis and acute renal failure in a child with influenza A infection. Pediatr Nephrol. 1997 Jun;11(3):363-5. Abstract

158. Dietzman DE, Schaller JG, Ray CG, et al. Acute myositis associated with influenza B infection. Pediatrics. 1976 Feb;57(2):255-8. Abstract

159. Brinar VV, Habek M, Brinar M, et al. The differential diagnosis of acute transverse myelitis. Clin Neurol Neurosurg. 2006 Mar;108(3):278-83. Abstract

160. Ropper AH. The Guillain-Barré syndrome. N Engl J Med. 1992 Apr 23;326(17):1130-6. Abstract

161. MacDonald K, Osterholm M, Hedberg C, et al. Toxic shock syndrome: a newly recognized complication of influenza and influenza-like illness. JAMA. 1987 Feb 27;257(8):1053-8. Abstract

162. US Food and Drug Administration. FDA warns of fraudulent and unapproved flu products. Mar 2018 [internet publication].Full text