Last reviewed: 4 Feb 2021
Last updated: 11 Oct 2019
Summary
Definition
History and exam
Other diagnostic factors
- headache
- fatigue
- pleuritic chest pain
- dyspnoea
- myalgia or arthralgia
- weight loss
- night sweats
- chills
- rales, rhonchi, wheeze, or rub
- bronchial breathing
- haemoptysis
- pyopneumothorax
- lymphadenopathy
- abnormal mental status or neurological examination
Risk factors
- occupation involving digging or construction
- recreational activities that increase likelihood of dust inhalation
- extremes of age
- male sex
- residing in or visiting endemic areas
- African-American or Filipino ancestry
- immunosuppression, especially suppression of cell-mediated immunity
- blood group B
- pregnancy
- HLA groups
- diabetes mellitus
Diagnostic investigations
1st investigations to order
- sputum culture
- enzyme immunoassay serology for coccidioidomycosis
- immunodiffusion serology for coccidioidomycosis
- complement fixation serology for coccidioidomycosis
- FBC
- chest x-ray
Investigations to consider
- lung biopsy
- lumbar puncture
- erythrocyte sedimentation rate
- CT chest
- bone scan
- MRI
Treatment algorithm
ACUTE
Contributors
Authors
Professor of Medicine
Mayo Clinic College of Medicine and Sciences
Rochester
MN
Division of Infectious Diseases
Mayo Clinic
Phoenix
AZ
Disclosures
JEB declares that she has no competing interests.
Peer reviewers
Infectious Diseases Clinic
Sanford Health Sioux Falls
SD
Disclosures
SH declares that she has no competing interests.
Professor of Medicine
Department of Hygiene and Medical Microbiology
Medical University Innsbruck
Innsbruck
Austria
Disclosures
AM declares that she has no competing interests.
Use of this content is subject to our disclaimer