Evaluation of olfactory loss

References

Key articles

Hummel T, Whitcroft KL, Andrews P, et al. Position paper on olfactory dysfunction. Rhinology. 2016 Jan 31;56(1):1-30.Full text  Abstract

Patel ZM, Holbrook EH, Turner JH, et al. International consensus statement on allergy and rhinology: olfaction. Int Forum Allergy Rhinol. 2022 Apr;12(4):327-680.Full text  Abstract

Miwa T, Ikeda K, Ishibashi T, et al. Clinical practice guidelines for the management of olfactory dysfunction - secondary publication. Auris Nasus Larynx. 2019 Oct;46(5):653-62.Full text  Abstract

Reference articles

1. Hummel T, Whitcroft KL, Andrews P, et al. Position paper on olfactory dysfunction. Rhinology. 2016 Jan 31;56(1):1-30.Full text  Abstract

2. Schubert CR, Cruickshanks KJ, Fischer ME, et al. Olfactory impairment in an adult population: the Beaver Dam Offspring Study. Chem Senses. 2012 May;37(4):325-34.Full text  Abstract

3. Desiato VM, Levy DA, Byun YJ, et al. The prevalence of olfactory dysfunction in the general population: a systematic review and meta-analysis. Am J Rhinol Allergy. 2021 Mar;35(2):195-205.Full text  Abstract

4. Pinto JM, Wroblewski KE, Kern DW, et al. The Rate of Age-Related Olfactory Decline Among the General Population of Older U.S. Adults. J Gerontol A Biol Sci Med Sci. 2015 Nov;70(11):1435-41.Full text  Abstract

5. Seubert J, Laukka EJ, Rizzuto D, et al. Prevalence and correlates of olfactory dysfunction in old age: a population-based Study. J Gerontol A Biol Sci Med Sci. 2017 Aug 1;72(8):1072-9.Full text  Abstract

6. Pinto JM, Schumm LP, Wroblewski KE, et al. Racial disparities in olfactory loss among older adults in the United States. J Gerontol A Biol Sci Med Sci. 2014 Mar;69(3):323-9.Full text  Abstract

7. Deems DA, Doty RL, Settle RG, et al. Smell and taste disorders, a study of 750 patients from the University of Pennsylvania Smell and Taste Center. Arch Otolaryngol Head Neck Surg. 1991;117:519-528. Abstract

8. Seiden AM, Duncan HJ. The diagnosis of a conductive olfactory loss. Laryngoscope. 2001 Jan;111(1):9-14. Abstract

9. Hoekman PK, Houlton JJ, Seiden AM. The utility of magnetic resonance imaging in the diagnostic evaluation of idiopathic olfactory loss. Laryngoscope. 2014 Feb;124(2):365-8. Abstract

10. Jafek BW, Hartman L, Eller PM, et al. Postviral olfactory dysfunction. Am J Rhinol. 1990 May;4(3):91-100.

11. Lindemann B, Ogiwara Y, Ninomiya Y. The discovery of umami. Chem Senses. 2002 Nov;27(9):843-4.

12. Kohli P, Naik AN, Farhood Z, et al. Olfactory outcomes after endoscopic sinus surgery for chronic rhinosinusitis: a meta-analysis. Otolaryngol Head Neck Surg. 2016 Dec;155(6):936-48. Abstract

13. Harris R, Davidson TM, Murphy C, et al. Clinical evaluation and symptoms of chemosensory impairment: 1000 consecutive cases from the nasal dysfunction clinic in San Diego. Am J Rhinol. 2006 Jan-Feb;20(1):101-8. Abstract

14. Konstantinidis I, Tsakiropoulou E, Bekiaridou P, et al. Use of olfactory training in post-traumatic and postinfectious olfactory dysfunction. Laryngoscope. 2013 Dec;123(12):E85-90.

15. Pekala K, Chandra RK, Turner JH. Efficacy of olfactory training in patients with olfactory loss: a systematic review and meta-analysis. Int Forum Allergy Rhinol. 2016 Mar;6(3):299-307.Full text  Abstract

16. Patel ZM, Holbrook EH, Turner JH, et al. International consensus statement on allergy and rhinology: olfaction. Int Forum Allergy Rhinol. 2022 Apr;12(4):327-680.Full text  Abstract

17. Hummel T, Lötsch J. Prognostic factors of olfactory dysfunction. Arch Otolaryngol Head Neck Surg. 2010 Apr;136(4):347-51.Full text  Abstract

18. London B, Nabet B, Fisher AR, et al. Predictors of prognosis in patients with olfactory disturbance. Ann Neurol. 2008 Feb;63(2):159-66. Abstract

19. Duncan HJ, Seiden AM. Long-term follow-up of olfactory loss secondary to head trauma and upper respiratory tract infection. Arch Otolaryngol Head Neck Surg. 1995 Oct;121(10):1183-7. Abstract

20. Cavazzana A, Larsson M, Münch M, et al. Postinfectious olfactory loss: a retrospective study on 791 patients. Laryngoscope. 2018 Jan;128(1):10-5. Abstract

21. Addison AB, Wong B, Ahmed T, et al. Clinical Olfactory Working Group consensus statement on the treatment of postinfectious olfactory dysfunction. J Allergy Clin Immunol. 2021 May;147(5):1704-19.Full text  Abstract

22. Butowt R, Bilińska K, von Bartheld C. Why does the omicron variant largely spare olfactory function? Implications for the pathogenesis of anosmia in coronavirus disease 2019. J Infect Dis. 2022 Oct 17;226(8):1304-8.Full text  Abstract

23. von Bartheld CS, Wang L. Prevalence of olfactory dysfunction with the omicron variant of SARS-CoV-2: a systematic review and meta-analysis. Cells. 2023 Jan 28;12(3).Full text  Abstract

24. Hannum ME, Ramirez VA, Lipson SJ, et al. Objective sensory testing methods reveal a higher prevalence of olfactory loss in COVID-19-positive patients compared to subjective methods: a systematic review and meta-analysis. Chem Senses. 2020 Dec 5;45(9):865-74.Full text  Abstract

25. Lerner DK, Garvey KL, Arrighi-Allisan AE, et al. Clinical features of parosmia associated with COVID-19 infection. Laryngoscope. 2022 Mar;132(3):633-9.Full text  Abstract

26. Wei G, Gu J, Gu Z, et al. Olfactory dysfunction in patients with coronavirus disease 2019: A Review. Front Neurol. 2021;12:783249.Full text  Abstract

27. Tan HQM, Pendolino AL, Andrews PJ, et al. Prevalence of olfactory dysfunction and quality of life in hospitalised patients 1 year after SARS-CoV-2 infection: a cohort study. BMJ Open. 2022 Jan 25;12(1):e054598.Full text  Abstract

28. Howell J, Costanzo RM, Reiter ER. Head trauma and olfactory function. World J Otorhinolaryngol Head Neck Surg. 2018 Mar;4(1):39-45.Full text  Abstract

29. Collet S, Grulois V, Bertrand B, et al. Post-traumatic olfactory dysfunction: a cohort study and update. B-ENT. 2009;5 Suppl 13:97-107. Abstract

30. Temmel AF, Quint C, Schickinger-Fischer B, et al. Characteristics of olfactory disorders in relation to major causes of olfactory loss. Arch Otolaryngol Head Neck Surg. 2002 Jun;128(6):635-41.Full text  Abstract

31. Singh R, Humphries T, Mason S, et al. The incidence of anosmia after traumatic brain injury: the SHEFBIT cohort. Brain Inj. 2018;32(9):1122-8.Full text  Abstract

32. Haxel BR, Grant L, Mackay-Sim A. Olfactory dysfunction after head injury. J Head Trauma Rehabil. 2008 Nov-Dec;23(6):407-13. Abstract

33. Doty RL, Yousem DM, Pham LT, et al. Olfactory dysfunction in patients with head trauma. Arch Neurol. 1997 Sep;54(9):1131-40. Abstract

34. Kern RC. Chronic sinusitis and anosmia: pathologic changes in the olfactory mucosa. Laryngoscope. 2000 Jul;110(7):1071-7. Abstract

35. Konstantinidis I, Witt M, Kaidoglou K, et al. Olfactory mucosa in nasal polyposis: implications for FESS outcome. Rhinology. 2010 Mar;48(1):47-53. Abstract

36. Yee KK, Pribitkin EA, Cowart BJ, et al. Neuropathology of the olfactory mucosa in chronic rhinosinusitis. Am J Rhinol Allergy. 2010 Mar-Apr;24(2):110-20. Abstract

37. Kohli P, Naik AN, Harruff EE, et al. The prevalence of olfactory dysfunction in chronic rhinosinusitis. Laryngoscope. 2017;127:309-20. Abstract

38. Ajmani GS, Suh HH, Pinto JM. Effects of ambient air pollution exposure on olfaction: a review. Environ Health Perspect. 2016 Nov;124(11):1683-93.Full text  Abstract

39. Amoore JE. Effects of chemical exposure on olfaction in humans. In: Barrow CS, ed. Toxicology of the nasal passages. Washington. DC: Hemisphere Publishing; 1986;263-73.

40. Upadhyay UD, Holbrook EH. Olfactory loss as a result of toxic exposure. Otolaryngol Clin N Amer. 2004 Dec;37(6):1185-207. Abstract

41. Jafek BW, Linschoten MR, Murrow BW. Anosmia after intranasal zinc gluconate use. Am J Rhinol. 2004 May-Jun;18(3):137-41. Abstract

42. Alexander TH, Davidson TM. Intranasal zinc and anosmia: the zinc-induced anosmia syndrome. Laryngoscope. 2006 Feb;116(2):217-20. Abstract

43. Doty RL, Bromley SM. Effects of drugs on olfaction and taste. Otolaryngol Clin North Am. 2004 Dec;37(6):1229-54. Abstract

44. Comeau TB, Epstein JB, Migas C. Taste and smell dysfunction in patients receiving chemotherapy: a review of current knowledge. Support Care Cancer. 2001 Nov;9(8):575-80. Abstract

45. Ophir D, Guterman A, Gross-Isseroff R. Changes in smell acuity induced by radiation exposure of the olfactory mucosa. Arch Otolaryngol Head Neck Surg. 1988 Aug;114(8):853-5. Abstract

46. Hosemann W, Gode U, Wigand ME. Indications, technique, and results of endonasal endoscopic ethmoidectomy. Acta Otorhinolaryngol Belg. 1993;47(1):73-83. Abstract

47. Kovacs T. Mechanisms of olfactory dysfunction in aging and neurodegenerative disorders. Ageing Res Rev. 2004 Apr;3(2):215-32. Abstract

48. Dintica CS, Marseglia A, Rizzuto D, et al. Impaired olfaction is associated with cognitive decline and neurodegeneration in the brain. Neurology. 2019 Feb 12;92(7):e700-9.Full text  Abstract

49. Devanand DP, Michaels-Marston KS, Liu X, et al. Olfactory deficits in patients with mild cognitive impairment predict Alzheimer's disease at follow-up. Am J Psychiatry. 2000 Sep;157(9):1399-405. Abstract

50. Wilson RS, Arnold SE, Buchman AS, et al. Odor identification and progression of parkinsonian signs in older persons. Exp Aging Res. 2008 Jul-Sep;34(3):173-87. Abstract

51. Iannilli E, Stephan L, Hummel T, et al. Olfactory impairment in Parkinson's disease is a consequence of central nervous system decline. J Neurol. 2017 Jun;264(6):1236-46. Abstract

52. Gottschlich S, Ambrosch P, Kramkowski D, et al. Head and neck manifestations of Wegener's granulomatosis. Rhinology. 2006 Dec;44(4):227-33. Abstract

53. Xu X, Geng L, Chen C, et al. Olfactory impairment in patients with primary Sjogren's syndrome and its correlation with organ involvement and immunological abnormalities. Arthritis Res Ther. 2021 Sep 29;23(1):250.Full text  Abstract

54. Goodspeed RB, Gent JF, Catalanotto FA. Chemosensory dysfunction. Clinical evaluation results from a taste and smell clinic. Postgrad Med. 1987 Jan;81(1):251-7. Abstract

55. John H, Schmid C. Kallmann's syndrome: clues to clinical diagnosis. Int J Impot Res. 2000 Apr;12(2):121-3. Abstract

56. Hamilton BE, Weissman JL. Imaging of chemosensory loss. Otolaryngol Clin N Amer. 2004 Dec;37(6):1255-80. Abstract

57. Doty RL, Shaman P, Dann M. Development of the University of Pennsylvania Smell Identification Test: a standardized microencapsulated test of olfactory function. Physiol Behav. 1984 Mar;32(3):489-502. Abstract

58. Miwa T, Ikeda K, Ishibashi T, et al. Clinical practice guidelines for the management of olfactory dysfunction - secondary publication. Auris Nasus Larynx. 2019 Oct;46(5):653-62.Full text  Abstract

59. Bramerson A, Johansson L, Ek L, et al. Prevalence of olfactory dysfunction: the Skovde population-based study. Laryngoscope. 2004 Apr;114(4):733-7. Abstract

60. Murphy C, Schubert CR, Cruickshanks KJ, et al. Prevalence of olfactory impairment in older adults. JAMA. 2002 Nov 13;288(8):2307-12. Abstract

61. Hummel T, Sekinger B, Wolf SR, et al. "Sniffin' sticks": olfactory performance assessed by the combined testing of odor identification, odor discrimination, and olfactory threshold. Chem Senses. 1997 Feb;22(1):39-52. Abstract

62. Frank RA, Gesteland RC, Bailie J, et al. Characterization of the Sniff Magnitude Test. Arch Otolaryngol Head Neck Surg. 2006 May;132(5):532-6. Abstract

63. Davidson TM, Murphy C. Rapid clinical evaluation of anosmia: the alcohol sniff test. Arch Otolaryngol Head Neck Surg. 1997 Jun;123(6):591-4. Abstract

64. Ikeda K, Sakurada T, Suzaki Y, et al. Efficacy of systemic corticosteroid treatment for anosmia with nasal and paranasal sinus disease. Rhinology. 1995 Sep;33(3):162-5. Abstract

65. Mott A, Cain W, Lafreniere D, et al. Topical corticosteroid treatment of anosmia associated with nasal and sinus disease. Arch Otolaryngol Head Neck Surg. 1997 Apr;123(4):367-72. Abstract

Use of this content is subject to our disclaimer