Pituitary adenomas occur in 15% to 20% of normal subjects in autopsy and radiological studies. Growth hormone secreting tumours make up around 20% of pituitary tumours. Acromegaly is a rare condition with an insidious onset, often resulting in diagnostic delay. The total prevalence ranges between 2.8 and 13.7 cases per 100,000 people, with an annual incidence rate between 0.2 and 1.1 cases per 100,000 people. Acromegaly is often recognised in middle-aged men or women but can occur at any age. The disease is equally distributed between both sexes.
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