References
Key articles
American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed, text revision (DSM-5-TR). Washington, DC: American Psychiatric Association; 2022.Full text
Yatham LN, Chakrabarty T, Bond DJ, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) recommendations for the management of patients with bipolar disorder with mixed presentations. Bipolar Disord. 2021 Dec;23(8):767-88. Abstract
Yatham LN, Kennedy SH, Parikh SV, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar Disord. 2018 Mar;20(2):97-170.Full text Abstract
National Institute for Health and Care Excellence. Bipolar disorder: assessment and management. Dec 2023 [internet publication].Full text
Goodwin GM, Haddad PM, Ferrier IN, et al. Evidence-based guidelines for treating bipolar disorder: revised third edition recommendations from the British Association for Psychopharmacology. J Psychopharmacol. 2016 Jun;30(6):495-553.Full text Abstract
Fountoulakis KN, Grunze H, Vieta E, et al. The International College of Neuro-Psychopharmacology (CINP) treatment guidelines for bipolar disorder in adults (CINP-BD-2017), Part 3: the clinical guidelines. Int J Neuropsychopharmacol. 2017 Feb 1;20(2):180-95.Full text Abstract
Reference articles
1. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed, text revision (DSM-5-TR). Washington, DC: American Psychiatric Association; 2022.Full text
2. World Health Organization. ICD-11 for mortality and morbidity statistics. Feb 2024 [internet publication].Full text
3. Vázquez GH, Lolich M, Cabrera C, et al. Mixed symptoms in major depressive and bipolar disorders: a systematic review. J Affect Disord. 2018 Jan 1;225:756-60. Abstract
4. Seo HJ, Wang HR, Jun TY, et al. Factors related to suicidal behavior in patients with bipolar disorder: the effect of mixed features on suicidality. Gen Hosp Psychiatry. 2016 Mar-Apr;39:91-6. Abstract
5. Yatham LN, Chakrabarty T, Bond DJ, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) recommendations for the management of patients with bipolar disorder with mixed presentations. Bipolar Disord. 2021 Dec;23(8):767-88. Abstract
6. Munk-Olsen T, Laursen TM, Meltzer-Brody S, et al. Psychiatric disorders with postpartum onset: possible early manifestations of bipolar affective disorders. Arch Gen Psychiatry. 2012 Apr;69(4):428-34.Full text Abstract
7. McIntyre RS, Konarski JZ, Yatham LN. Comorbidity in bipolar disorder: a framework for rational treatment selection. Hum Psychopharmacol. 2004 Aug;19(6):369-86. Abstract
8. Preti A, Vrublevska J, Veroniki AA, et al. Prevalence and treatment of panic disorder in bipolar disorder: systematic review and meta-analysis. Evid Based Ment Health. 2018 May;21(2):53-60. Abstract
9. Compton WM, Thomas YF, Stinson FS, et al. Prevalence, correlates, disability, and comorbidity of DSM-IV drug abuse and dependence in the United States: results from the national epidemiologic survey on alcohol and related conditions. Arch Gen Psychiatry. 2007 May;64(5):566-76.Full text Abstract
10. Preti A, Vrublevska J, Veroniki AA, et al. Prevalence, impact and treatment of generalised anxiety disorder in bipolar disorder: a systematic review and meta-analysis. Evid Based Ment Health. 2016 Aug;19(3):73-81.Full text Abstract
11. Grant BF, Stinson FS, Hasin DS, et al. Prevalence, correlates, and comorbidity of bipolar I disorder and axis I and II disorders: results from the national epidemiologic survey on alcohol and related conditions. J Clin Psychiatry. 2005 Oct;66(10):1205-15. Abstract
12. Ayerbe L, Forgnone I, Addo J, et al. Hypertension risk and clinical care in patients with bipolar disorder or schizophrenia; a systematic review and meta-analysis. J Affect Disord. 2018 Jan 1;225:665-70. Abstract
13. Fornaro M, Orsolini L, Marini S, et al. The prevalence and predictors of bipolar and borderline personality disorders comorbidity: Systematic review and meta-analysis. J Affect Disord. 2016 May;195:105-18. Abstract
14. Schiavone P, Dorz S, Conforti D, et al. Comorbidity of DSM-IV personality disorders in unipolar and bipolar affective disorders: a comparative study. Psychol Rep. 2004 Aug;95(1):121-8. Abstract
15. Mantere O, Melartin TK, Suominen K, et al. Differences in axis I and II comorbidity between bipolar I and II disorders and major depressive disorder. J Clin Psychiatry. 2006 Apr;67(4):584-93. Abstract
16. Salvi V, Ribuoli E, Servasi M, et al. ADHD and bipolar disorder in adulthood: clinical and treatment implications. Medicina (Kaunas). 2021 May 10;57(5):466.Full text Abstract
17. Kessing LV, Willer I, Andersen PK, et al. Rate and predictors of conversion from unipolar to bipolar disorder: a systematic review and meta-analysis. Bipolar Disord. 2017 Aug;19(5):324-35. Abstract
18. Angst J, Sellaro R, Stassen HH, et al. Diagnostic conversion from depression to bipolar disorders: results of a long-term prospective study of hospital admissions. J Affect Disord. 2005 Feb;84(2-3):149-57. Abstract
19. Merikangas KR, Jin R, He JP, et al. Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative. Arch Gen Psychiatry. 2011 Mar;68(3):241-51.Full text Abstract
20. McGrath JJ, Al-Hamzawi A, Alonso J, et al. Age of onset and cumulative risk of mental disorders: a cross-national analysis of population surveys from 29 countries. Lancet Psychiatry. 2023 Sep;10(9):668-81. Abstract
21. Kessler RC, Kazdin AE, Aguilar-Gaxiola S, et al. Patterns and correlates of patient-reported helpfulness of treatment for common mental and substance use disorders in the WHO World Mental Health Surveys. World Psychiatry. 2022 Jun;21(2):272-86.Full text Abstract
22. Merikangas KR, Akiskal HS, Angst J, et al. Lifetime and 12-month prevalence of bipolar spectrum disorder in the national comorbidity survey replication. Arch Gen Psychiatry. 2007 May;64(5):543-52.Full text Abstract
23. Rowland TA, Marwaha S. Epidemiology and risk factors for bipolar disorder. Ther Adv Psychopharmacol. 2018 Sep;8(9):251-69.Full text Abstract
24. Humpston CS, Bebbington P, Marwaha S. Bipolar disorder: prevalence, help-seeking and use of mental health care in England - findings from the 2014 adult psychiatric morbidity survey. J Affect Disord. 2021 Mar 1;282:426-33. Abstract
25. Cerimele JM, Chwastiak LA, Dodson S, et al. The prevalence of bipolar disorder in general primary care samples: a systematic review. Gen Hosp Psychiatry. 2014 Jan-Feb;36(1):19-25.Full text Abstract
26. Sharma V, Doobay M, Baczynski C. Bipolar postpartum depression: an update and recommendations. J Affect Disord. 2017 Sep;219:105-11. Abstract
27. Hirschfeld RM, Lewis L, Vornik LA. Perceptions and impact of bipolar disorder: how far have we really come? Results of the national depressive and manic-depressive association 2000 survey of individuals with bipolar disorder. J Clin Psychiatry. 2003 Feb;64(2):161-74. Abstract
28. Dagani J, Signorini G, Nielssen O, et al. Meta-analysis of the interval between the onset and management of bipolar disorder. Can J Psychiatry. 2017 Apr;62(4):247-58.Full text Abstract
29. Judd LL, Akiskal HS, Schettler PJ, et al. The long-term natural history of the weekly symptomatic status of bipolar I disorder. Arch Gen Psychiatry. 2002 Jun;59(6):530-7.Full text Abstract
30. Goodwin FK, Jamison KR. Manic-depressive illness: bipolar disorders and recurrent depression. 2nd ed. New York, NY: Oxford University Press; 2007.
31. Dong M, Lu L, Zhang L, et al. Prevalence of suicide attempts in bipolar disorder: a systematic review and meta-analysis of observational studies. Epidemiol Psychiatr Sci. 2019 Oct 25;29:e63.Full text Abstract
32. Miller JN, Black DW. Bipolar disorder and suicide: a review. Curr Psychiatry Rep. 2020 Jan 18;22(2):6. Abstract
33. Dome P, Rihmer Z, Gonda X. Suicide risk in bipolar disorder: a brief review. Medicina (Kaunas). 2019 Jul 24;55(8):403.Full text Abstract
34. Slama F, Bellivier F, Henry C, et al. Bipolar patients with suicidal behavior: toward the identification of a clinical subgroup. J Clin Psychiatry. 2004 Aug;65(8):1035-9. Abstract
35. Yatham LN, Kennedy SH, Parikh SV, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar Disord. 2018 Mar;20(2):97-170.Full text Abstract
36. Kendler KS. From many to one to many-the search for causes of psychiatric illness. JAMA Psychiatry. 2019 Oct 1;76(10):1085-91. Abstract
37. Baum AE, Akula N, Cabanero M, et al. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry. 2008 Feb;13(2):197-207. Abstract
38. Song J, Bergen SE, Kuja-Halkola R, et al. Bipolar disorder and its relation to major psychiatric disorders: a family-based study in the Swedish population. Bipolar Disord. 2015 Mar;17(2):184-93. Abstract
39. Smoller JW, Finn CT. Family, twin, and adoption studies of bipolar disorder. Am J Med Genet C Semin Med Genet. 2003 Nov 15;123C(1):48-58. Abstract
40. Lichtenstein P, Yip BH, Björk C, et al. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet. 2009 Jan 17;373(9659):234-9. Abstract
41. Craddock N, Sklar P. Genetics of bipolar disorder: successful start to a long journey. Trends Genet. 2009 Feb;25(2):99-105. Abstract
42. Quidé Y, Tozzi L, Corcoran M, et al. The impact of childhood trauma on developing bipolar disorder: current understanding and ensuring continued progress. Neuropsychiatr Dis Treat. 2020 Dec 14;16:3095-115.Full text Abstract
43. Etain B, Aas M. Childhood maltreatment in bipolar disorders. Curr Top Behav Neurosci. 2021;48:277-301. Abstract
44. Garno JL, Goldberg JF, Ramirez PM, et al. Impact of childhood abuse on the clinical course of bipolar disorder. Br J Psychiatry. 2005 Feb;186:121-5.Full text Abstract
45. Post RM, Altshuler LL, Kupka R, et al. Verbal abuse, like physical and sexual abuse, in childhood is associated with an earlier onset and more difficult course of bipolar disorder. Bipolar Disord. 2015 May;17(3):323-30. Abstract
46. Mullins N, Forstner AJ, O'Connell KS, et al. Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology. Nat Genet. 2021 Jun;53(6):817-29. Abstract
47. Goes FS. Genetics of bipolar disorder: recent update and future directions. Psychiatr Clin North Am. 2016 Mar;39(1):139-55. Abstract
48. Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 2011 Sep 18;43(10):977-83.Full text Abstract
49. Nurnberger JI Jr, Koller DL, Jung J, et al; Psychiatric Genomics Consortium Bipolar Group. Identification of pathways for bipolar disorder: a meta-analysis. JAMA Psychiatry. 2014 Jun;71(6):657-64.Full text Abstract
50. Marshe VS, Pira S, Mantere O, et al. C-reactive protein and cardiovascular risk in bipolar disorder patients: a systematic review. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 3;79(Pt b):442-51. Abstract
51. Solmi M, Suresh Sharma M, Osimo EF, et al. Peripheral levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and interleukin-1β across the mood spectrum in bipolar disorder: a meta-analysis of mean differences and variability. Brain Behav Immun. 2021 Oct;97:193-203. Abstract
52. Kempton MJ, Salvador Z, Munafò MR, et al. Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder. Arch Gen Psychiatry. 2011 Jul;68(7):675-90.Full text Abstract
53. Hibar DP, Westlye LT, van Erp TG, et al. Subcortical volumetric abnormalities in bipolar disorder. Mol Psychiatry. 2016 Dec;21(12):1710-6.Full text Abstract
54. Adler CM, DelBello MP, Jarvis K, et al. Voxel-based study of structural changes in first-episode patients with bipolar disorder. Biol Psychiatry. 2007 Mar 15;61(6):776-81. Abstract
55. Hibar DP, Westlye LT, Doan NT, et al. Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group. Mol Psychiatry. 2018 Apr;23(4):932-42.Full text Abstract
56. Selvaraj S, Arnone D, Job D, et al. Grey matter differences in bipolar disorder: a meta-analysis of voxel-based morphometry studies. Bipolar Disord. 2012 Mar;14(2):135-45. Abstract
57. Phillips ML, Ladouceur CD, Drevets WC. A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder. Mol Psychiatry. 2008 Sep;13(9):829, 833-57.Full text Abstract
58. Kraguljac NV, Reid M, White D, et al. Neurometabolites in schizophrenia and bipolar disorder - a systematic review and meta-analysis. Psychiatry Res. 2012 Aug-Sep;203(2-3):111-25.Full text Abstract
59. Rosenblat JD, McIntyre RS. Bipolar disorder and inflammation. Psychiatr Clin North Am. 2016 Mar;39(1):125-37. Abstract
60. Rosenblat JD, McIntyre RS. Bipolar disorder and immune dysfunction: epidemiological findings, proposed pathophysiology and clinical implications. Brain Sci. 2017 Oct 30;7(11):144.Full text Abstract
61. Sayana P, Colpo GD, Simões LR, et al. A systematic review of evidence for the role of inflammatory biomarkers in bipolar patients. J Psychiatr Res. 2017 Sep;92:160-82. Abstract
62. Goldstein BI, Kemp DE, Soczynska JK, et al. Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literature. J Clin Psychiatry. 2009 Aug;70(8):1078-90. Abstract
63. Vancampfort D, Stubbs B, Mitchell AJ, et al. Risk of metabolic syndrome and its components in people with schizophrenia and related psychotic disorders, bipolar disorder and major depressive disorder: a systematic review and meta-analysis. World Psychiatry. 2015 Oct;14(3):339-47.Full text Abstract
64. Belvederi Murri M, Prestia D, Mondelli V, et al. The HPA axis in bipolar disorder: systematic review and meta-analysis. Psychoneuroendocrinology. 2016 Jan;63:327-42. Abstract
65. Akiskal HS, Benazzi F. The DSM-IV and ICD-10 categories of recurrent (major) depressive and bipolar II disorders: evidence that they lie on a dimensional spectrum. J Affect Disord. 2006 May;92(1):45-54. Abstract
66. Muzina DJ, Kemp DE, Yatham LN, et al. Bipolar depression: diagnosis and treatment. In: Yatham LN and Kusumakar V, eds. Bipolar disorder: a clinician's guide to treatment management. New York, NY: Routledge; 2009.
67. de Zwarte SMC, Brouwer RM, Agartz I, et al. The association between familial risk and brain abnormalities is disease specific: an ENIGMA-relatives study of schizophrenia and bipolar disorder. Biol Psychiatry. 2019 Oct 1;86(7):545-56.Full text Abstract
68. Coryell W, Endicott J, Maser JD, et al. Long-term stability of polarity distinctions in the affective disorders. Am J Psychiatry. 1995 Mar;152(3):385-90. Abstract
69. Kupfer DJ, Frank E, Grochocinski VJ, et al. Demographic and clinical characteristics of individuals in a bipolar disorder case registry. J Clin Psychiatry. 2002 Feb;63(2):120-5. Abstract
70. Lewinsohn PM, Klein DN, Seeley JR. Bipolar disorder during adolescence and young adulthood in a community sample. Bipolar Disord. 2000 Sep;2(3 Pt 2):281-93. Abstract
71. Alloy LB, Abramson LY, Urosevic S, et al. The psychosocial context of bipolar disorder: environmental, cognitive, and developmental risk factors. Clin Psychol Rev. 2005 Dec;25(8):1043-75. Abstract
72. Gilman SE, Ni MY, Dunn EC, et al. Contributions of the social environment to first-onset and recurrent mania. Mol Psychiatry. 2015 Mar;20(3):329-36. Abstract
73. McKay MT, Cannon M, Chambers D, et al. Childhood trauma and adult mental disorder: a systematic review and meta-analysis of longitudinal cohort studies. Acta Psychiatr Scand. 2021 Mar;143(3):189-205. Abstract
74. Pavlova B, Perlis RH, Alda M, et al. Lifetime prevalence of anxiety disorders in people with bipolar disorder: a systematic review and meta-analysis. Lancet Psychiatry. 2015 Aug;2(8):710-7. Abstract
75. Otto MW, Simon NM, Wisniewski SR, et al. Prospective 12-month course of bipolar disorder in out-patients with and without comorbid anxiety disorders. Br J Psychiatry. 2006 Jul;189:20-5.Full text Abstract
76. McIntyre RS, Nguyen HT, Soczynska JK, et al. Medical and substance-related comorbidity in bipolar disorder: translational research and treatment opportunities. Dialogues Clin Neurosci. 2008;10(2):203-13.Full text Abstract
77. Fagiolini A, Kupfer DJ, Houck PR, et al. Obesity as a correlate of outcome in patients with bipolar I disorder. Am J Psychiatry. 2003 Jan;160(1):112-7.Full text Abstract
78. Fagiolini A, Kupfer DJ, Rucci P, et al. Suicide attempts and ideation in patients with bipolar I disorder. J Clin Psychiatry. 2004 Apr;65(4):509-14. Abstract
79. Elmslie JL, Silverstone JT, Mann JI, et al. Prevalence of overweight and obesity in bipolar patients. J Clin Psychiatry. 2000 Mar;61(3):179-84. Abstract
80. Bartels SJ, Pratt SI, Aschbrenner KA, et al. Pragmatic replication trial of health promotion coaching for obesity in serious mental illness and maintenance of outcomes. Am J Psychiatry. 2015 Apr;172(4):344-52.Full text Abstract
81. Launders N, Kirsh L, Osborn DPJ, et al. The temporal relationship between severe mental illness diagnosis and chronic physical comorbidity: a UK primary care cohort study of disease burden over 10 years. Lancet Psychiatry. 2022 Sep;9(9):725-35.Full text Abstract
82. Nierenberg AA, Agustini B, Köhler-Forsberg O, et al. Diagnosis and treatment of bipolar disorder: a review. JAMA. 2023 Oct 10;330(14):1370-80. Abstract
83. McIntyre RS, Berk M, Brietzke E, et al. Bipolar disorders. Lancet. 2020 Dec 5;396(10265):1841-56. Abstract
84. American College of Obstetricians and Gynecologists. Screening and diagnosis of mental health conditions during pregnancy and postpartum: ACOG clinical practice guideline no. 4. Obstet Gynecol. 2023 Jun 1;141(6):1232-61. Abstract
85. Jamison KR. Great wits and madness: more near allied? Br J Psychiatry. 2011 Nov;199(5):351-2.Full text Abstract
86. Cloutier M, Greene M, Guerin A, et al. The economic burden of bipolar I disorder in the United States in 2015. J Affect Disord. 2018 Jan 15;226:45-51.Full text Abstract
87. Vieta E, Salagre E, Grande I, et al. Early intervention in bipolar disorder. Am J Psychiatry. 2018 May 1;175(5):411-26.Full text Abstract
88. Saraf G, Moazen-Zadeh E, Pinto JV, et al. Early intervention for people at high risk of developing bipolar disorder: a systematic review of clinical trials. Lancet Psychiatry. 2021 Jan;8(1):64-75. Abstract
89. Muzina DJ. Bipolar spectrum disorder: differential diagnosis and treatment. Prim Care. 2007 Sep;34(3):521-50;vi. Abstract
90. Muzina DJ, Kemp DE, McIntyre RS. Differentiating bipolar disorders from major depressive disorders: treatment implications. Ann Clin Psychiatry. 2007 Oct-Dec;19(4):305-12. Abstract
91. Spitzer RL, Williams JB, Kroenke K, et al. Utility of a new procedure for diagnosing mental disorders in primary care: the PRIME-MD 1000 study. JAMA. 1994 Dec 14;272(22):1749-56. Abstract
92. Spitzer RL, Kroenke K, Williams JB; Patient Health Questionnaire Primary Care Study Group. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. JAMA. 1999 Nov 10;282(18):1737-44.Full text Abstract
93. Kroenke K, Spitzer RL, Williams JB. The patient health questionnaire-2: validity of a two-item depression screener. Med Care. 2003 Nov;41(11):1284-92. Abstract
94. McIntyre RS, Patel MD, Masand PS, et al. The Rapid Mood Screener (RMS): a novel and pragmatic screener for bipolar I disorder. Curr Med Res Opin. 2021 Jan;37(1):135-44.Full text Abstract
95. Hirschfeld RM, Calabrese JR, Weissman MM, et al. Screening for bipolar disorder in the community. J Clin Psychiatry. 2003 Jan;64(1):53-9. Abstract
96. Aiken CB, Weisler RH, Sachs GS. The bipolarity index: a clinician-rated measure of diagnostic confidence. J Affect Disord. 2015 May 15;177:59-64. Abstract
97. Young RC, Biggs JT, Ziegler VE, et al. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry. 1978 Nov;133:429-35. Abstract
98. Vancampfort D, Vansteelandt K, Correll CU, et al. Metabolic syndrome and metabolic abnormalities in bipolar disorder: a meta-analysis of prevalence rates and moderators. Am J Psychiatry. 2013 Mar;170(3):265-74.Full text Abstract
99. De Crescenzo F, Economou A, Sharpley AL, et al. Actigraphic features of bipolar disorder: a systematic review and meta-analysis. Sleep Med Rev. 2017 Jun;33:58-69. Abstract
100. National Institute for Health and Care Excellence. Bipolar disorder: assessment and management. Dec 2023 [internet publication].Full text
101. Anderson IM, Haddad PM, Scott J. Bipolar disorder. BMJ. 2012 Dec 27;345:e8508. Abstract
102. US Preventive Services Task Force. Depression in adults: screening. January 2016 [internet publication].Full text
103. Goodwin GM, Haddad PM, Ferrier IN, et al. Evidence-based guidelines for treating bipolar disorder: revised third edition recommendations from the British Association for Psychopharmacology. J Psychopharmacol. 2016 Jun;30(6):495-553.Full text Abstract
104. Bschor T, Baethge C, Grunze H, et al. German S3 guidelines on bipolar disorders-first update 2019 : what is new in pharmacotherapy? [in German]. Nervenarzt. Mar 2020;91(3):216-21. Abstract
105. Fountoulakis KN, Grunze H, Vieta E, et al. The International College of Neuro-Psychopharmacology (CINP) treatment guidelines for bipolar disorder in adults (CINP-BD-2017), Part 3: the clinical guidelines. Int J Neuropsychopharmacol. 2017 Feb 1;20(2):180-95.Full text Abstract
106. Malhi GS, Bell E, Boyce P, et al. The 2020 Royal Australian and New Zealand College of psychiatrists clinical practice guidelines for mood disorders: Bipolar disorder summary. Bipolar Disord. 2020 Dec;22(8):805-21.Full text Abstract
107. Goes FS. Diagnosis and management of bipolar disorders. BMJ. 2023 Apr 12;381:e073591.Full text Abstract
108. Lomholt LH, Andersen DV, Sejrsgaard-Jacobsen C, et al. Mortality rate trends in patients diagnosed with schizophrenia or bipolar disorder: a nationwide study with 20 years of follow-up. Int J Bipolar Disord. 2019 Mar 1;7(1):6.Full text Abstract
109. Ali T, Sisay M, Tariku M, et al. Antipsychotic-induced extrapyramidal side effects: a systematic review and meta-analysis of observational studies. PLoS One. 2021;16(9):e0257129.Full text Abstract
110. Garriga M, Pacchiarotti I, Kasper S, et al. Assessment and management of agitation in psychiatry: expert consensus. World J Biol Psychiatry. 2016;17(2):86-128. Abstract
111. Faurholt-Jepsen M, Frost M, Busk J, et al. Is smartphone-based mood instability associated with stress, quality of life, and functioning in bipolar disorder? Bipolar Disord. 2019 Nov;21(7):611-20. Abstract
112. Faurholt-Jepsen M, Frost M, Christensen EM, et al. The association between mixed symptoms, irritability and functioning measured using smartphones in bipolar disorder. Acta Psychiatr Scand. 2019 May;139(5):443-53. Abstract
113. Goulding EH, Dopke CA, Rossom R, et al. Effects of a smartphone-based self-management intervention for individuals with bipolar disorder on relapse, symptom burden, and quality of life: a randomized clinical trial. JAMA Psychiatry. 2023 Feb 1;80(2):109-18.Full text Abstract
114. Anmella G, Faurholt-Jepsen M, Hidalgo-Mazzei D, et al. Smartphone-based interventions in bipolar disorder: systematic review and meta-analyses of efficacy. a position paper from the International Society for Bipolar Disorders (ISBD) Big Data Task Force. Bipolar Disord. 2022 Sep;24(6):580-614.Full text Abstract
115. Hidalgo-Mazzei D, Berk M, Cipriani A, et al. Treatment-resistant and multi-therapy-resistant criteria for bipolar depression: consensus definition. Br J Psychiatry. 2019 Jan;214(1):27-35.Full text Abstract
116. Cipriani A, Barbui C, Salanti G, et al. Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis. Lancet. 2011 Oct 8;378(9799):1306-15. Abstract
117. World Health Organization. Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders. 2023 [internet publication].Full text
118. Sachs GS, Grossman F, Ghaemi SN, et al. Combination of a mood stabilizer with risperidone or haloperidol for treatment of acute mania: a double-blind, placebo-controlled comparison of efficacy and safety. Am J Psychiatry. 2002 Jul;159(7):1146-54.Full text Abstract
119. Müller-Oerlinghausen B, Retzow A, Henn FA, et al. Valproate as an adjunct to neuroleptic medication for the treatment of acute episodes of mania: a prospective, randomized, double-blind, placebo-controlled, multicenter study. European Valproate Mania Study Group. J Clin Psychopharmacol. 2000 Apr;20(2):195-203. Abstract
120. Tohen M, Chengappa KN, Suppes T, et al. Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy. Arch Gen Psychiatry. 2002 Jan;59(1):62-9.Full text Abstract
121. Sachs G, Chengappa KN, Suppes T, et al. Quetiapine with lithium or divalproex for the treatment of bipolar mania: a randomized, double-blind, placebo-controlled study. Bipolar Disord. 2004 Jun;6(3):213-23. Abstract
122. McKnight RF, de La Motte de Broöns de Vauvert SJGN, Chesney E, et al. Lithium for acute mania. Cochrane Database Syst Rev. 2019 Jun 1;(6):CD004048.Full text Abstract
123. Malhi GS, Tanious M, Das P, et al. The science and practice of lithium therapy. Aust N Z J Psychiatry. 2012 Mar;46(3):192-211. Abstract
124. Perugi G, Medda P, Toni C, et al. The role of electroconvulsive therapy (ECT) in bipolar disorder: effectiveness in 522 patients with bipolar depression, mixed-state, mania and catatonic features. Curr Neuropharmacol. 2017 Apr;15(3):359-71.Full text Abstract
125. National Institute for Health and Care Excellence. Guidance on the use of electroconvulsive therapy. October 2009 [internet publication].Full text
126. Valenti M, Benabarre A, Garcia-Amador M, et al. Electroconvulsive therapy in the treatment of mixed states in bipolar disorder. Eur Psychiatry. 2008 Jan;23(1):53-6. Abstract
127. Satre DD, Parthasarathy S, Young-Wolff KC, et al. Cost-effectiveness of motivational interviewing to reduce alcohol and cannabis use among patients with depression. J Stud Alcohol Drugs. 2022 Sep;83(5):662-71. Abstract
128. Sidor MM, MacQueen GM. Antidepressants for the acute treatment of bipolar depression: a systematic review and meta-analysis. J Clin Psychiatry. 2011 Feb;72(2):156-67. Abstract
129. McGirr A, Vöhringer PA, Ghaemi SN, et al. Safety and efficacy of adjunctive second-generation antidepressant therapy with a mood stabiliser or an atypical antipsychotic in acute bipolar depression: a systematic review and meta-analysis of randomised placebo-controlled trials. Lancet Psychiatry. 2016 Dec;3(12):1138-46. Abstract
130. Geddes JR, Calabrese JR, Goodwin GM. Lamotrigine for treatment of bipolar depression: independent meta-analysis and meta-regression of individual patient data from five randomised trials. Br J Psychiatry. 2009 Jan;194(1):4-9.Full text Abstract
131. Loebel A, Cucchiaro J, Silva R, et al. Lurasidone monotherapy in the treatment of bipolar I depression: a randomized, double-blind, placebo-controlled study. Am J Psychiatry. 2014 Feb;171(2):160-8.Full text Abstract
132. Yildiz A, Siafis S, Mavridis D, et al. Comparative efficacy and tolerability of pharmacological interventions for acute bipolar depression in adults: a systematic review and network meta-analysis. Lancet Psychiatry. 2023 Sep;10(9):693-705. Abstract
133. Kemp DE, Ganocy SJ, Brecher M, et al. Clinical value of early partial symptomatic improvement in the prediction of response and remission during short-term treatment trials in 3369 subjects with bipolar I or II depression. J Affect Disord. 2011 Apr;130(1-2):171-9.Full text Abstract
134. Tohen M, Vieta E, Calabrese J, et al. Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. Arch Gen Psychiatry. 2003 Nov;60(11):1079-88.Full text Abstract
135. Yatham LN, Vieta E, Durgam S, et al. Efficacy of cariprazine in bipolar depression: post hoc band‐pass analyses of 2 randomized, double‐blind, placebo‐controlled trials. Atlanta, Georgia: American Psychiatric Association Annual Meeting; 2016.
136. Yatham LN. A clinical review of aripiprazole in bipolar depression and maintenance therapy of bipolar disorder. J Affect Disord. 2011 Jan;128(suppl 1):S21-8. Abstract
137. McGirr A, Karmani S, Arsappa R, et al. Clinical efficacy and safety of repetitive transcranial magnetic stimulation in acute bipolar depression. World Psychiatry. 2016 Feb;15(1):85-6.Full text Abstract
138. Hirakawa H, Terao T, Muronaga M, et al. Adjunctive bright light therapy for treating bipolar depression: a systematic review and meta-analysis of randomized controlled trials. Brain Behav. 2020 Dec;10(12):e01876.Full text Abstract
139. Miklowitz DJ, Otto MW, Frank E, et al. Intensive psychosocial intervention enhances functioning in patients with bipolar depression: results from a 9-month randomized controlled trial. Am J Psychiatry. 2007 Sep;164(9):1340-7.Full text Abstract
140. Miklowitz DJ, Otto MW, Frank E, et al. Psychosocial treatments for bipolar depression: a 1-year randomized trial from the systematic treatment enhancement program. Arch Gen Psychiatry. 2007 Apr;64(4):419-26.Full text Abstract
141. Datto C, Pottorf WJ, Feeley L, et al. Bipolar II compared with bipolar I disorder: baseline characteristics and treatment response to quetiapine in a pooled analysis of five placebo-controlled clinical trials of acute bipolar depression. Ann Gen Psychiatry. 2016 Mar 11;15:9.Full text Abstract
142. Young AH, Calabrese JR, Gustafsson U, et al. Quetiapine monotherapy in bipolar II depression: combined data from four large, randomized studies. Int J Bipolar Disord. 2013 Jul 4;1:10.Full text Abstract
143. Jeong JH, Bahk WM, Woo YS, et al. Efficacy of quetiapine in patients with bipolar I and II depression: a multicenter, prospective, open-label, observational study. Neuropsychiatr Dis Treat. 2013;9:197-204.Full text Abstract
144. Ahn YM, Nam JY, Culver JL, et al. Lamotrigine plus quetiapine combination therapy in treatment-resistant bipolar depression. Ann Clin Psychiatry. 2011 Feb;23(1):17-24. Abstract
145. Altshuler LL, Sugar CA, McElroy SL, et al. Switch rates during acute treatment for bipolar II depression with lithium, sertraline, or the two combined: a randomized double-blind comparison. Am J Psychiatry. 2017 Mar 1;174(3):266-76.Full text Abstract
146. Amsterdam J. Efficacy and safety of venlafaxine in the treatment of bipolar II major depressive episode. J Clin Psychopharmacol. 1998 Oct;18(5):414-7. Abstract
147. Amsterdam JD, Garcia-España F. Venlafaxine monotherapy in women with bipolar II and unipolar major depression. J Affect Disord. 2000 Sep;59(3):225-9. Abstract
148. Swartz HA, Frank E, Cheng Y. A randomized pilot study of psychotherapy and quetiapine for the acute treatment of bipolar II depression. Bipolar Disord. 2012 Mar;14(2):211-6.Full text Abstract
149. Pacchiarotti I, Bond DJ, Baldessarini RJ, et al. The International Society for Bipolar Disorders (ISBD) task force report on antidepressant use in bipolar disorders. Am J Psychiatry. 2013 Nov;170(11):1249-62.Full text Abstract
150. Fountoulakis KN, Kontis D, Gonda X, et al. Treatment of mixed bipolar states. Int J Neuropsychopharmacol. 2012 Aug;15(7):1015-26.Full text Abstract
151. McIntyre RS, Tohen M, Berk M, et al. DSM-5 mixed specifier for manic episodes: evaluating the effect of depressive features on severity and treatment outcome using asenapine clinical trial data. J Affect Disord. 2013 Sep 5;150(2):378-83. Abstract
152. Berk M, Tiller JW, Zhao J, et al. Effects of asenapine in bipolar I patients meeting proxy criteria for moderate-to-severe mixed major depressive episodes: a post hoc analysis. J Clin Psychiatry. 2015 Jun;76(6):728-34.Full text Abstract
153. McIntyre RS, Masand PS, Earley W, et al. Cariprazine for the treatment of bipolar mania with mixed features: a post hoc pooled analysis of 3 trials. J Affect Disord. 2019 Oct 1;257:600-6.Full text Abstract
154. Swann AC, Bowden CL, Morris D, et al. Depression during mania. treatment response to lithium or divalproex. Arch Gen Psychiatry. 1997 Jan;54(1):37-42. Abstract
155. Suppes T, Eudicone J, McQuade R, et al. Efficacy and safety of aripiprazole in subpopulations with acute manic or mixed episodes of bipolar I disorder. J Affect Disord. 2008 Apr;107(1-3):145-54. Abstract
156. Sachs G, Sanchez R, Marcus R, et al. Aripiprazole in the treatment of acute manic or mixed episodes in patients with bipolar I disorder: a 3-week placebo-controlled study. J Psychopharmacol. 2006 Jul;20(4):536-46. Abstract
157. Stahl S, Lombardo I, Loebel A, et al. Efficacy of ziprasidone in dysphoric mania: pooled analysis of two double-blind studies. J Affect Disord. 2010 Apr;122(1-2):39-45. Abstract
158. Tohen M, McIntyre RS, Kanba S, et al. Efficacy of olanzapine in the treatment of bipolar mania with mixed features defined by DSM-5. J Affect Disord. 2014 Oct;168:136-41. Abstract
159. Suppes T, Ketter TA, Gwizdowski IS, et al. First controlled treatment trial of bipolar II hypomania with mixed symptoms: quetiapine versus placebo. J Affect Disord. 2013 Aug 15;150(1):37-43. Abstract
160. Weisler RH, Hirschfeld R, Cutler AJ, et al. Extended-release carbamazepine capsules as monotherapy in bipolar disorder : pooled results from two randomised, double-blind, placebo-controlled trials. CNS Drugs. 2006;20(3):219-31. Abstract
161. Gonzalez-Pinto A, Lalaguna B, Mosquera F, et al. Use of olanzapine in dysphoric mania. J Affect Disord. 2001 Oct;66(2-3):247-53. Abstract
162. Gonzalez-Pinto A, Tohen M, Lalaguna B, et al. Treatment of bipolar I rapid cycling patients during dysphoric mania with olanzapine. J Clin Psychopharmacol. 2002 Oct;22(5):450-4. Abstract
163. McIntyre RS, Suppes T, Earley W, et al. Cariprazine efficacy in bipolar I depression with and without concurrent manic symptoms: post hoc analysis of 3 randomized, placebo-controlled studies. CNS Spectr. 2020 Aug;25(4):502-10.Full text Abstract
164. McIntyre RS, Cucchiaro J, Pikalov A, et al. Lurasidone in the treatment of bipolar depression with mixed (subsyndromal hypomanic) features: post hoc analysis of a randomized placebo-controlled trial. J Clin Psychiatry. 2015 Apr;76(4):398-405.Full text Abstract
165. Tohen M, Kanba S, McIntyre RS, et al. Efficacy of olanzapine monotherapy in the treatment of bipolar depression with mixed features. J Affect Disord. 2014 Aug;164:57-62. Abstract
166. Benazzi F, Berk M, Frye MA, et al. Olanzapine/fluoxetine combination for the treatment of mixed depression in bipolar I disorder: a post hoc analysis. J Clin Psychiatry. 2009 Oct;70(10):1424-31. Abstract
167. Suttajit S, Srisurapanont M, Maneeton N, et al. Quetiapine for acute bipolar depression: a systematic review and meta-analysis. Drug Des Devel Ther. 2014;8:827-38.Full text Abstract
168. Kishi T, Ikuta T, Sakuma K, et al. Comparison of quetiapine immediate- and extended-release formulations for bipolar depression: a systematic review and network meta-analysis of double-blind, randomized placebo-controlled trials. J Psychiatr Res. 2019 Aug;115:121-8. Abstract
169. Scherk H, Pajonk FG, Leucht S. Second-generation antipsychotic agents in the treatment of acute mania: a systematic review and meta-analysis of randomized controlled trials. Arch Gen Psychiatry. 2007 Apr;64(4):442-55.Full text Abstract
170. Weisler RH, Nolen WA, Neijber A, et al. Continuation of quetiapine versus switching to placebo or lithium for maintenance treatment of bipolar I disorder (Trial 144: a randomized controlled study). J Clin Psychiatry. 2011 Nov;72(11):1452-64. Abstract
171. Patkar A, Gilmer W, Pae CU, et al. A 6 week randomized double-blind placebo-controlled trial of ziprasidone for the acute depressive mixed state. PLoS One. 2012;7(4):e34757.Full text Abstract
172. Frye MA, Helleman G, McElroy SL, et al. Correlates of treatment-emergent mania associated with antidepressant treatment in bipolar depression. Am J Psychiatry. 2009 Feb;166(2):164-72.Full text Abstract
173. Swann AC, Lafer B, Perugi G, et al. Bipolar mixed states: an international society for bipolar disorders task force report of symptom structure, course of illness, and diagnosis. Am J Psychiatry. 2013 Jan;170(1):31-42.Full text Abstract
174. Azorin JM, Sapin C, Weiller E. Effect of asenapine on manic and depressive symptoms in bipolar I patients with mixed episodes: results from post hoc analyses. J Affect Disord. 2013 Feb 15;145(1):62-9. Abstract
175. McIntyre RS, Cohen M, Zhao J, et al. A 3-week, randomized, placebo-controlled trial of asenapine in the treatment of acute mania in bipolar mania and mixed states. Bipolar Disord. 2009 Nov;11(7):673-86. Abstract
176. Baldessarini RJ, Hennen J, Wilson M, et al. Olanzapine versus placebo in acute mania: treatment responses in subgroups. J Clin Psychopharmacol. 2003 Aug;23(4):370-6. Abstract
177. Houston JP, Tohen M, Degenhardt EK, et al. Olanzapine-divalproex combination versus divalproex monotherapy in the treatment of bipolar mixed episodes: a double-blind, placebo-controlled study. J Clin Psychiatry. 2009 Nov;70(11):1540-7. Abstract
178. Weisler RH, Kalali AH, Ketter TA, et al. A multicenter, randomized, double-blind, placebo-controlled trial of extended-release carbamazepine capsules as monotherapy for bipolar disorder patients with manic or mixed episodes. J Clin Psychiatry. 2004 Apr;65(4):478-84. Abstract
179. Hirschfeld RM, Bowden CL, Vigna NV, et al. A randomized, placebo-controlled, multicenter study of divalproex sodium extended-release in the acute treatment of mania. J Clin Psychiatry. 2010 Apr;71(4):426-32. Abstract
180. Keck PE Jr, Versiani M, Potkin S, et al. Ziprasidone in the treatment of acute bipolar mania: a three-week, placebo-controlled, double-blind, randomized trial. Am J Psychiatry. 2003 Apr;160(4):741-8.Full text Abstract
181. Tohen M, Castillo J, Pope HG Jr, et al. Concomitant use of valproate and carbamazepine in bipolar and schizoaffective disorders. J Clin Psychopharmacol. 1994 Feb;14(1):67-70. Abstract
182. Ciapparelli A, Dell'Osso L, Tundo A, et al. Electroconvulsive therapy in medication-nonresponsive patients with mixed mania and bipolar depression. J Clin Psychiatry. 2001 Jul;62(7):552-5. Abstract
183. Medda P, Perugi G, Zanello S, et al. Comparative response to electroconvulsive therapy in medication-resistant bipolar I patients with depression and mixed state. J ECT. 2010 Jun;26(2):82-6. Abstract
184. Medda P, Toni C, Mariani MG, et al. Electroconvulsive therapy in 197 patients with a severe, drug-resistant bipolar mixed state: treatment outcome and predictors of response. J Clin Psychiatry. 2015 Sep;76(9):1168-73. Abstract
185. Palma M, Ferreira B, Borja-Santos N, et al. Efficacy of electroconvulsive therapy in bipolar disorder with mixed features. Depress Res Treat. 2016;2016:8306071.Full text Abstract
186. Fountoulakis KN, Kontis D, Gonda X, et al. A systematic review of the evidence on the treatment of rapid cycling bipolar disorder. Bipolar Disord. 2013 Mar;15(2):115-37. Abstract
187. Muzina DJ. Pharmacologic treatment of rapid cycling and mixed states in bipolar disorder: an argument for the use of lithium. Bipolar Disord. 2009 Jun;11(suppl 2):84-91. Abstract
188. Rihmer Z. Lithium treatment and the risk of suicide in affective disorders. Eur Psych Review. 2011;4:55-8.
189. Mignogna KM, Goes FS. Characterizing the longitudinal course of symptoms and functioning in bipolar disorder. Psychol Med. 2024 Jan;54(1):79-89.Full text Abstract
190. Cullen C, Kappelmann N, Umer M, et al. Efficacy and acceptability of pharmacotherapy for comorbid anxiety symptoms in bipolar disorder: a systematic review and meta-analysis. Bipolar Disord. 2021 Dec;23(8):754-66. Abstract
191. Stokes PRA, Jokinen T, Amawi S, et al. Pharmacological treatment of mood disorders and comorbid addictions: a systematic review and meta-analysis: Traitement Pharmacologique des Troubles de L'humeur et des Dépendances Comorbides: Une Revue Systématique et une Méta-Analyse. Can J Psychiatry. 2020 Nov;65(11):749-69.Full text Abstract
192. Schneider-Thoma J, Efthimiou O, Bighelli I, et al. Second-generation antipsychotic drugs and short-term somatic serious adverse events: a systematic review and meta-analysis. Lancet Psychiatry. 2019 Sep;6(9):753-65. Abstract
193. Public Health England. Preconception interventions and resources for women with serious mental illness. Mar 2021 [internet publication].Full text
194. American College of Obstetricians and Gynecologists. Treatment and management of mental health conditions during pregnancy and postpartum: ACOG Clinical Practice guideline No. 5. Obstet Gynecol. 2023 Jun 1;141(6):1262-88. Abstract
195. Medicines and Healthcare products Regulatory Agency. Valproate use by women and girls. February 2021 [internet publication].Full text
196. Brohan E, Chowdhary N, Dua T, et al. The WHO Mental Health Gap Action Programme for mental, neurological, and substance use conditions: the new and updated guideline recommendations. Lancet Psychiatry. 2024 Feb;11(2):155-8. Abstract
197. American Epilepsy Society. Position statement on the use of valproate by women of childbearing potential. Jun 2021 [internet publication].Full text
198. European Medicines Agency. New measures to avoid valproate exposure in pregnancy endorsed. Mar 2018 [internet publication].Full text
199. Viguera AC, Nonacs R, Cohen LS, et al. Risk of recurrence of bipolar disorder in pregnant and nonpregnant women after discontinuing lithium maintenance. Am J Psychiatry. 2000 Feb;157(2):179-84.Full text Abstract
200. Freeman MP, Smith KW, Freeman SA, et al. The impact of reproductive events on the course of bipolar disorder in women. J Clin Psychiatry. 2002 Apr;63(4):284-7. Abstract
201. Rusner M, Berg M, Begley C. Bipolar disorder in pregnancy and childbirth: a systematic review of outcomes. BMC Pregnancy Childbirth. 2016 Oct 28;16(1):331.Full text Abstract
202. Wesseloo R, Kamperman AM, Munk-Olsen T, et al. Risk of postpartum relapse in bipolar disorder and postpartum psychosis: a systematic review and meta-analysis. Am J Psychiatry. 2016 Feb 1;173(2):117-27.Full text Abstract
203. Di Florio A, Gordon-Smith K, Forty L, et al. Stratification of the risk of bipolar disorder recurrences in pregnancy and postpartum. Br J Psychiatry. 2018 Sep;213(3):542-7.Full text Abstract
204. Larsen ER, Saric K. Pregnancy and bipolar disorder: the risk of recurrence when discontinuing treatment with mood stabilisers: a systematic review. Acta Neuropsychiatr. 2017 Oct;29(5):259-66. Abstract
205. Taylor VH, Steiner M, Soares C. Bipolar disorders in women: special issues. In: Yatham LN and Kusumakar V, eds. Bipolar disorder: a clinician's guide to treatment management. New York, NY: Routledge; 2009.
206. Iqbal MM, Sohhan T, Mahmud SZ. The effects of lithium, valproic acid, and carbamazepine during pregnancy and lactation. J Toxicol Clin Toxicol. 2001;39(4):381-92. Abstract
207. Yonkers KA, Wisner KL, Stowe Z, et al. Management of bipolar disorder during pregnancy and the postpartum period. Am J Psychiatry. 2004 Apr;161(4):608-20.Full text Abstract
208. Munk-Olsen T, Liu X, Viktorin A, et al. Maternal and infant outcomes associated with lithium use in pregnancy: an international collaborative meta-analysis of six cohort studies. Lancet Psychiatry. 2018 Aug;5(8):644-52. Abstract
209. Fornaro M, Maritan E, Ferranti R, et al. Lithium exposure during pregnancy and the postpartum period: a systematic review and meta-analysis of safety and efficacy outcomes. Am J Psychiatry. 2020 Jan 1;177(1):76-92.Full text Abstract
210. Patorno E, Huybrechts KF, Bateman BT, et al. Lithium use in pregnancy and the risk of cardiac malformations. N Engl J Med. 2017 Jun 8;376(23):2245-54.Full text Abstract
211. Wesseloo R, Wierdsma AI, van Kamp IL, et al. Lithium dosing strategies during pregnancy and the postpartum period. Br J Psychiatry. 2017 Jul;211(1):31-6. Abstract
212. Luykx JJ, Di Florio A, Bergink V. Prevention of infanticide and suicide in the postpartum period-the importance of emergency care. JAMA Psychiatry. 2019 Dec 1;76(12):1221-2. Abstract
213. Viguera AC, Whitfield T, Baldessarini RJ, et al. Risk of recurrence in women with bipolar disorder during pregnancy: prospective study of mood stabilizer discontinuation. Am J Psychiatry. 2007 Dec;164(12):1817-24; quiz 1923.Full text Abstract
214. Leiknes KA, Cooke MJ, Jarosch-von Schweder L, et al. Electroconvulsive therapy during pregnancy: a systematic review of case studies. Arch Womens Ment Health. 2015 Feb;18(1):1-39.Full text Abstract
215. Colom F, Vieta E, Martinez-Aran A, et al. Clinical factors associated with treatment noncompliance in euthymic bipolar patients. J Clin Psychiatry. 2000 Aug;61(8):549-55. Abstract
216. Sajatovic M, Davies M, Hrouda DR. Enhancement of treatment adherence among patients with bipolar disorder. Psychiatr Serv. 2004 Mar;55(3):264-9.Full text Abstract
217. Santos Pina L, Bouckaert F, Obbels J, et al. Maintenance electroconvulsive therapy in severe bipolar disorder: a retrospective chart review. J ECT. 2016 Mar;32(1):23-8. Abstract
218. Miklowitz DJ, Efthimiou O, Furukawa TA, et al. Adjunctive psychotherapy for bipolar disorder: a systematic review and component network meta-analysis. JAMA Psychiatry. 2021 Feb 1;78(2):141-50.Full text Abstract
219. Batista TA, von Werne Baes C, Juruena MF. Efficacy of psychoeducation in bipolar patients: systematic review of randomized trials. Psychol Neurosci. 2011;4:409-16.Full text
220. Morriss RK, Faizal MA, Jones AP, et al. Interventions for helping people recognise early signs of recurrence in bipolar disorder. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD004854. Abstract
221. Ball JR, Mitchell PB, Corry JC, et al. A randomized controlled trial of cognitive therapy for bipolar disorder: focus on long-term change. J Clin Psychiatry. 2006 Feb;67(2):277-86. Abstract
222. Macheiner T, Skavantzos A, Pilz R, et al. A meta-analysis of adjuvant group-interventions in psychiatric care for patients with bipolar disorders. J Affect Disord. 2017 Nov;222:28-31. Abstract
223. Werneke U, Ott M, Renberg ES, et al. A decision analysis of long-term lithium treatment and the risk of renal failure. Acta Psychiatr Scand. 2012 Sep;126(3):186-97.Full text Abstract
224. Miura T, Noma H, Furukawa TA, et al. Comparative efficacy and tolerability of pharmacological treatments in the maintenance treatment of bipolar disorder: a systematic review and network meta-analysis. Lancet Psychiatry. 2014 Oct;1(5):351-9. Abstract
225. Cipriani A, Hawton K, Stockton S, et al. Lithium in the prevention of suicide in mood disorders: updated systematic review and meta-analysis. BMJ. 2013 Jun 27;346:f3646.Full text Abstract
226. Lähteenvuo M, Tanskanen A, Taipale H, et al. Real-world effectiveness of pharmacologic treatments for the prevention of rehospitalization in a Finnish nationwide cohort of patients with bipolar disorder. JAMA Psychiatry. 2018 Apr 1;75(4):347-55. Abstract
227. McIntyre RS, Cohen M, Zhao J, et al. Asenapine for long-term treatment of bipolar disorder: a double-blind 40-week extension study. J Affect Disord. 2010 Nov;126(3):358-65. Abstract
228. Hashimoto Y, Kotake K, Watanabe N, et al. Lamotrigine in the maintenance treatment of bipolar disorder. Cochrane Database Syst Rev. 2021 Sep 15;9(9):CD013575.Full text Abstract
229. Harlin M, Yildirim M, Such P, et al. A randomized, open-label, multiple-dose, parallel-arm, pivotal study to evaluate the safety, tolerability, and pharmacokinetics of aripiprazole 2-month long-acting injectable in adults with schizophrenia or bipolar I disorder. CNS Drugs. 2023 Apr;37(4):337-50.Full text Abstract
230. Vieta E, Suppes T, Ekholm B, et al. Long-term efficacy of quetiapine in combination with lithium or divalproex on mixed symptoms in bipolar I disorder. J Affect Disord. 2012 Dec 15;142(1-3):36-44. Abstract
231. Bowden CL, Calabrese JR, Sachs G, et al. A placebo-controlled 18-month trial of lamotrigine and lithium maintenance treatment in recently manic or hypomanic patients with bipolar I disorder. Arch Gen Psychiatry. 2003 Apr;60(4):392-400.Full text Abstract
232. Yatham LN, Beaulieu S, Schaffer A, et al. Optimal duration of risperidone or olanzapine adjunctive therapy to mood stabilizer following remission of a manic episode: a CANMAT randomized double-blind trial. Mol Psychiatry. 2016 Aug;21(8):1050-6.Full text Abstract
233. Bond DJ, Pratoomsri W, Yatham LN. Depot antipsychotic medications in bipolar disorder: a review of the literature. Acta Psychiatr Scand Suppl. 2007;(434):3-16. Abstract
234. Vieta E, Montgomery S, Sulaiman AH, et al. A randomized, double-blind, placebo-controlled trial to assess prevention of mood episodes with risperidone long-acting injectable in patients with bipolar I disorder. Eur Neuropsychopharmacol. 2012 Nov;22(11):825-35. Abstract
235. Tohen M, Calabrese JR, Sachs GS, et al. Randomized, placebo-controlled trial of olanzapine as maintenance therapy in patients with bipolar I disorder responding to acute treatment with olanzapine. Am J Psychiatry. 2006 Feb;163(2):247-56.Full text Abstract
236. Quiroz JA, Yatham LN, Palumbo JM, et al. Risperidone long-acting injectable monotherapy in the maintenance treatment of bipolar I disorder. Biol Psychiatry. 2010 Jul 15;68(2):156-62. Abstract
237. Macfadden W, Alphs L, Haskins JT, et al. A randomized, double-blind, placebo-controlled study of maintenance treatment with adjunctive risperidone long-acting therapy in patients with bipolar I disorder who relapse frequently. Bipolar Disord. 2009 Dec;11(8):827-39.Full text Abstract
238. Berwaerts J, Melkote R, Nuamah I, et al. A randomized, placebo- and active-controlled study of paliperidone extended-release as maintenance treatment in patients with bipolar I disorder after an acute manic or mixed episode. J Affect Disord. 2012 May;138(3):247-58. Abstract
239. Young AH, McElroy SL, Olausson B, et al. A randomised, placebo-controlled 52-week trial of continued quetiapine treatment in recently depressed patients with bipolar I and bipolar II disorder. World J Biol Psychiatry. 2014 Feb;15(2):96-112. Abstract
240. Kane JM, Quitkin FM, Rifkin A, et al. Lithium carbonate and imipramine in the prophylaxis of unipolar and bipolar II illness: a prospective, placebo-controlled comparison. Arch Gen Psychiatry. 1982 Sep;39(9):1065-9. Abstract
241. Amsterdam JD, Lorenzo-Luaces L, Soeller I, et al. Short-term venlafaxine v. lithium monotherapy for bipolar type II major depressive episodes: effectiveness and mood conversion rate. Br J Psychiatry. 2016 Apr;208(4):359-65.Full text Abstract
242. Calabrese JR, Suppes T, Bowden CL, et al. A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. J Clin Psychiatry. 2000 Nov;61(11):841-50. Abstract
243. Dunner DL, Fieve RR. Clinical factors in lithium carbonate prophylaxis failure. Arch Gen Psychiatry. 1974 Feb;30(2):229-33. Abstract
244. Tondo L, Baldessarini RJ, Floris G. Long-term clinical effectiveness of lithium maintenance treatment in types I and II bipolar disorders. Br J Psychiatry. 2001 Jun;178(suppl 41):S184-90. Abstract
245. Amsterdam JD, Lorenzo-Luaces L, Soeller I, et al. Safety and effectiveness of continuation antidepressant versus mood stabilizer monotherapy for relapse-prevention of bipolar II depression: a randomized, double-blind, parallel-group, prospective study. J Affect Disord. 2015 Oct 1;185:31-7.Full text Abstract
246. Tohen M, Sutton VK, Calabrese JR, et al. Maintenance of response following stabilization of mixed index episodes with olanzapine monotherapy in a randomized, double-blind, placebo-controlled study of bipolar 1 disorder. J Affect Disord. 2009 Jul;116(1-2):43-50. Abstract
247. Loo CK, Katalinic N, Mitchell PB. Physical treatments for bipolar disorder: a review of electroconvulsive therapy, stereotactic surgery and other brain stimulation techniques. J Affect Disord. 2011 Jul;132(1-2):1-13. Abstract
248. Muzina DJ, Kemp DE, Calabrese JR. Mood stabilizers. In: Tasman A, Kay J, Lieberman JA, et al, eds. Psychiatry. 3rd ed. Chichester, UK: John Wiley & Sons; 2008.
249. Sachs GS, Nierenberg AA, Calabrese JR, et al. Effectiveness of adjunctive antidepressant treatment for bipolar depression. N Engl J Med. 2007 Apr 26;356(17):1711-22.Full text Abstract
250. Calabrese JR, Durgam S, Satlin A, et al. Efficacy and safety of lumateperone for major depressive episodes associated with bipolar I or bipolar II disorder: a phase 3 randomized placebo-controlled trial. Am J Psychiatry. 2021 Dec;178(12):1098-106.Full text Abstract
251. Monahan C, McCoy L, Powell J, et al. Olanzapine/samidorphan: new drug approved for treating bipolar I disorder and schizophrenia. Ann Pharmacother. 2022 Sep;56(9):1049-57. Abstract
252. Torres R, Czeisler EL, Chadwick SR, et al. Efficacy and safety of Iloperidone in bipolar mania: a double-blind, placebo-controlled study. J Clin Psychiatry. 2024 Jan 15;85(1):23m14966.Full text Abstract
253. Preskorn SH, Zeller S, Citrome L, et al. Effect of sublingual dexmedetomidine vs placebo on acute agitation associated with bipolar disorder: a randomized clinical trial. JAMA. 2022 Feb 22;327(8):727-36.Full text Abstract
254. Zarate CA, Brutsche NE, Ibrahim L, et al. Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial. Biol Psychiatry. 2012 Jun 1;71(11):939-46.Full text Abstract
255. Martinotti G, Dell'Osso B, Di Lorenzo G, et al. Treating bipolar depression with esketamine: Safety and effectiveness data from a naturalistic multicentric study on esketamine in bipolar versus unipolar treatment-resistant depression. Bipolar Disord. 2023 May;25(3):233-44.Full text Abstract
256. McIntyre RS, Lipsitz O, Rodrigues NB, et al. The effectiveness of ketamine on anxiety, irritability, and agitation: Implications for treating mixed features in adults with major depressive or bipolar disorder. Bipolar Disord. 2020 Dec;22(8):831-40. Abstract
257. Kryst J, Kawalec P, Mitoraj AM, et al. Efficacy of single and repeated administration of ketamine in unipolar and bipolar depression: a meta-analysis of randomized clinical trials. Pharmacol Rep. 2020 Jun;72(3):543-62.Full text Abstract
258. Dean RL, Marquardt T, Hurducas C, et al. Ketamine and other glutamate receptor modulators for depression in adults with bipolar disorder. Cochrane Database Syst Rev. 2021 Oct 8;(10):CD011611.Full text Abstract
259. Rybakowski JK, Permoda-Osip A, Bartkowska-Sniatkowska A. Ketamine augmentation rapidly improves depression scores in inpatients with treatment-resistant bipolar depression. Int J Psychiatry Clin Pract. 2017 Jun;21(2):99-103. Abstract
260. ClinicalTrials.gov. A clinical study of an investigational drug for the treatment of major depressive episode associated with bipolar I disorder. ClinicalTrials.gov Identifier: NCT05169710. Nov 2023 [internet publication].Full text
261. Nery FG, Li W, DelBello MP, et al. N-acetylcysteine as an adjunctive treatment for bipolar depression: a systematic review and meta-analysis of randomized controlled trials. Bipolar Disord. 2021 Nov;23(7):707-14. Abstract
262. Zheng W, Zhang QE, Cai DB, et al. N-acetylcysteine for major mental disorders: a systematic review and meta-analysis of randomized controlled trials. Acta Psychiatr Scand. 2018 May;137(5):391-400. Abstract
263. Keshavarzi A, Sharifi A, Jahangard L, et al. Levetiracetam as an adjunctive treatment for mania: a double-blind, randomized, placebo-controlled trial. Neuropsychobiology. 2022;81(3):192-203.Full text Abstract
264. Zarezadeh F, Arbabi M, Shamabadi A, et al. Levetiracetam adjunct to quetiapine for the acute manic phase of bipolar disorder: a randomized, double-blind and placebo-controlled clinical trial of efficacy, safety and tolerability. Int Clin Psychopharmacol. 2022 Mar 1;37(2):46-53. Abstract
265. Park EM, Holmes JA, Reeder-Hayes KE. Acute mania associated with levetiracetam treatment. Psychosomatics. 2014 Jan-Feb;55(1):98-100.Full text Abstract
266. Josephson CB, Engbers JDT, Jette N, et al. Prediction tools for psychiatric adverse effects after levetiracetam prescription. JAMA Neurol. 2019 Apr 1;76(4):440-6.Full text Abstract
267. McIntyre RS, Lee Y, Zhou AJ, et al. The efficacy of psychostimulants in major depressive episodes: a systematic review and meta-analysis. J Clin Psychopharmacol. 2017 Aug;37(4):412-8. Abstract
268. Goldberg JF, Burdick KE, Endick CJ. Preliminary randomized, double-blind, placebo-controlled trial of pramipexole added to mood stabilizers for treatment-resistant bipolar depression. Am J Psychiatry. 2004 Mar;161(3):564-6.Full text Abstract
269. D'Urso G, Toscano E, Barone A, et al. Transcranial direct current stimulation for bipolar depression: systematic reviews of clinical evidence and biological underpinnings. Prog Neuropsychopharmacol Biol Psychiatry. 2023 Mar 8;121:110672. Abstract
270. Sampaio-Junior B, Tortella G, Borrione L, et al. Efficacy and safety of transcranial direct current stimulation as an add-on treatment for bipolar depression: a randomized clinical trial. JAMA Psychiatry. 2018 Feb 1;75(2):158-66. Abstract
271. Grunze H, Vieta E, Goodwin GM, et al. The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: acute and long-term treatment of mixed states in bipolar disorder. World J Biol Psychiatry. 2018 Feb;19(1):2-58. Abstract
272. Grunze H, Vieta E, Goodwin GM, et al. The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: update 2012 on the long-term treatment of bipolar disorder. World J Biol Psychiatry. 2013 Apr;14(3):154-219. Abstract
273. Grunze H, Vieta E, Goodwin GM, et al. The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: update 2010 on the treatment of acute bipolar depression. World J Biol Psychiatry. 2010 Mar;11(2):81-109. Abstract
274. Grunze H, Vieta E, Goodwin GM, et al. The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of bipolar disorders: update 2009 on the treatment of acute mania. World J Biol Psychiatry. 2009;10(2):85-116. Abstract
275. Solomon DA, Leon AC, Coryell WH, et al. Longitudinal course of bipolar I disorder: duration of mood episodes. Arch Gen Psychiatry. 2010 Apr;67(4):339-47.Full text Abstract
276. Judd LL, Akiskal HS, Schettler PJ, et al. A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder. Arch Gen Psychiatry. 2003 Mar;60(3):261-9.Full text Abstract
277. Inskip HM, Harris EC, Barraclough B. Lifetime risk of suicide for affective disorder, alcoholism and schizophrenia. Br J Psychiatry. 1998 Jan;172:35-7. Abstract
278. Muzina DJ. What physicians can do to prevent suicide. Cleve Clin J Med. 2004 Mar;71(3):242-50. Abstract
279. Wasserman D, Rihmer Z, Rujescu D, et al. The European Psychiatric Association (EPA) guidance on suicide treatment and prevention. Eur Psychiatry. 2012 Feb;27(2):129-41. Abstract
280. Smith EG, Austin KL, Kim HM, et al. Mortality associated with lithium and valproate treatment of US Veterans Health Administration patients with mental disorders. Br J Psychiatry. 2015 Jul;207(1):55-63. Abstract
281. Bora E. Neurocognitive features in clinical subgroups of bipolar disorder: a meta-analysis. J Affect Disord. 2018 Mar 15;229:125-34. Abstract
282. Clark L, Sahakian BJ. Cognitive neuroscience and brain imaging in bipolar disorder. Dialogues Clin Neurosci. 2008;10(2):153-63.Full text Abstract
283. Zwerling C, Whitten PS, Sprince NL, et al. Workforce participation by persons with disabilities: the national health interview survey disability supplement, 1994 to 1995. J Occup Environ Med. 2002 Apr;44(4):358-64. Abstract
284. Olfson M, Fireman B, Weissman MM, et al. Mental disorders and disability among patients in a primary care group practice. Am J Psychiatry. 1997 Dec;154(12):1734-40.Full text Abstract
285. Ray WA, Chung CP, Murray KT, et al. Atypical antipsychotic drugs and the risk of sudden cardiac death. N Engl J Med. 2009 Jan 15;360(3):225-35.Full text Abstract
286. Michelsen JW, Meyer JM. Cardiovascular effects of antipsychotics. Expert Rev Neurother. 2007 Jul;7(7):829-39. Abstract
287. Musil R, Obermeier M, Russ P, et al. Weight gain and antipsychotics: a drug safety review. Expert Opin Drug Saf. 2015 Jan;14(1):73-96. Abstract
288. D'Abreu A, Friedman JH. Tardive dyskinesia-like syndrome due to drugs that do not block dopamine receptors: rare or non-existent: literature review. Tremor Other Hyperkinet Mov (N Y). 2018;8:570.Full text Abstract
289. Dunne FJ. Lithium toxicity: the importance of clinical signs. Br J Hosp Med (Lond). 2010 Apr;71(4):206-10. Abstract
290. Baek JH, Kinrys G, Nierenberg AA. Lithium tremor revisited: pathophysiology and treatment. Acta Psychiatr Scand. 2014 Jan;129(1):17-23. Abstract
291. Azab AN, Shnaider A, Osher Y, et al. Lithium nephrotoxicity. Int J Bipolar Disord. 2015 Dec;3(1):28.Full text Abstract
292. Łukawska E, Frankiewicz D, Izak M, et al. Lithium toxicity and the kidney with special focus on nephrotic syndrome associated with the acute kidney injury: a case-based systematic analysis. J Appl Toxicol. 2021 Dec;41(12):1896-909. Abstract
293. Barbesino G. Drugs affecting thyroid function. Thyroid. 2010 Jul;20(7):763-70. Abstract
294. Nanau RM, Neuman MG. Adverse drug reactions induced by valproic acid. Clin Biochem. 2013 Oct;46(15):1323-38. Abstract
295. Bertolino JG. Carbamazepine. What physicians should know about its hematologic effects. Postgrad Med. 1990 Jul;88(1):183-6. Abstract
296. Calabrese JR, Sullivan JR, Bowden CL, et al. Rash in multicenter trials of lamotrigine in mood disorders: clinical relevance and management. J Clin Psychiatry. 2002 Nov;63(11):1012-9. Abstract
297. Physician's Desk Reference. Lamictal (lamotrigine): full prescribing information [internet publication].Full text
298. Faustino PR, Duarte GS, Chendo I, et al. Risk of developing Parkinson disease in bipolar disorder: a systematic review and meta-analysis. JAMA Neurol. 2020 Feb 1;77(2):192-8. Abstract
299. Chung DT, Ryan CJ, Hadzi-Pavlovic D, et al. Suicide rates after discharge from psychiatric facilities: a systematic review and meta-analysis. JAMA Psychiatry. 2017 Jul 1;74(7):694-702.Full text Abstract
300. Zaidi S, Heald AH, Belgamwar RB, et al. Monitoring drug interventions in people with bipolar disorder. BMJ. 2023 Feb 7;380:e070678. Abstract
301. Vornik LA, Brown ES. Management of comorbid bipolar disorder and substance abuse. J Clin Psychiatry. 2006;67 Suppl 7:24-30. Abstract
302. Jackson JG, Diaz FJ, Lopez L, et al. A combined analysis of worldwide studies demonstrates an association between bipolar disorder and tobacco smoking behaviors in adults. Bipolar Disord. 2015 Sep;17(6):575-97. Abstract
303. Public Health England. Preconception advice for women with serious mental illness. Mar 2021 [internet publication].Full text
Use of this content is subject to our disclaimer