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Impetigo

Last reviewed: 30 Mar 2025
Last updated: 27 Feb 2024

Summary

Definition

History and exam

Key diagnostic factors

  • vesicles/bullae
  • crusting
Full details

Other diagnostic factors

  • erythema
  • pruritus
  • pain
  • mucopurulent exudate
  • lymphadenopathy
  • fever
Full details

Risk factors

  • increased humidity
  • poor hygiene, malnutrition, and overcrowding
  • chronic colonization with Staphylococcus aureus - nasal, axillary, pharyngeal, perineal
  • concomitant skin disease
Full details

Diagnostic tests

1st tests to order

  • clinical diagnosis
Full details

Tests to consider

  • bacterial skin culture
Full details

Treatment algorithm

ACUTE

neonates: nonbullous impetigo

neonates: bullous impetigo

adults, children, and infants: superficial or limited infection

adults, children, and infants: widespread cutaneous lesions

adults, children, and infants: deep soft tissue infection or hematogenous spread

Contributors

Authors

Michael Freeman, MB BS, FACD, FRACGP

Dermatologist

Associate Professor

Bond University

Queensland

Australia

Disclosures

MF declares that he has no competing interests.

Acknowledgements

Dr Michael Freeman would like to gratefully acknowledge Dr Chris Del Mar, a previous contributor to this topic.

Disclosures

CDM declares that he has no competing interests.

Peer reviewers

Brian Swick, MD

Clinical Assistant Professor

University of Iowa College of Medicine

Iowa City

IA

Disclosures

BS declares that he has no competing interests.

Julian Trevino, MD

Associate Professor of Dermatology and Dermatology Residency Program Director

Boonshoft School of Medicine

Wright State University

Dayton

OH

Disclosures

Speaker's Bureau, Stiefel; Consultant, Abbott.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Hartman-Adams H, Banvard C, Juckett G. Impetigo: diagnosis and treatment. Am Fam Physician. 2014 Aug 15;90(4):229-35.Full text  Abstract

Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15;59(2):e10-52.Full text  Abstract

Koning S, van der Sande R, Verhagen AP, et al. Interventions for impetigo. Cochrane Database Syst Rev. 2012 Jan 18;(1):CD003261.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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  • Guidelines

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    • Practice guidelines for the diagnosis and management of skin and soft tissue infections
    More Guidelines
  • Patient information

    Impetigo

    More Patient information
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