The worldwide incidence of aortic dissection is 0.5 to 2.95 cases per 100,000 people annually. The incidence in the US is 0.2 to 0.8 cases per 100,000 people annually, resulting in about 2000 new cases each year. Aortic dissection may be more common in Europe; one prospective UK-based population study derived an incidence of 6 cases per 100,000 when out-of-hospital deaths were included. Men are predominantly affected, typically older than 50 years of age.
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