Narcolepsy

American Academy of Sleep Medicine. The AASM International classification of sleep disorders – third edition, text revision (ICSD-3-TR). Jun 2023 [internet publication].Full text

Smith MT, McCrae CS, Cheung J, et al. Use of actigraphy for the evaluation of sleep disorders and circadian rhythm sleep-wake disorders: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2018 Jul 15;14(7):1231-7.Full text  Abstract

Maski K, Trotti LM, Kotagal S, et al. Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2021 Sep 1;17(9):1881-93.Full text  Abstract

Bassetti CLA, Kallweit U, Vignatelli L, et al. European guideline and expert statements on the management of narcolepsy in adults and children. Eur J Neurol. 2021 Sep;28(9):2815-30.Full text  Abstract

Maski K, Trotti LM, Kotagal S, et al. Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment. J Clin Sleep Med. 2021 Sep 1;17(9):1895-945.Full text  Abstract

1. American Academy of Sleep Medicine. The AASM International classification of sleep disorders – third edition, text revision (ICSD-3-TR). Jun 2023 [internet publication].Full text

2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., text revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.

3. Berry BR, Gilmore RL. Narcolepsy and idiopathic hypersomnia. In: Carney PR, Berry RB, Geyer JD, eds. Clinical sleep disorders. Philadelphia, PA: Lippincot Williams and Wilkins; 2005.

4. Rosen GM, Bendel AE, Neglia JP, et al. Sleep in children with neoplasms of the central nervous system: case review of 14 children. Pediatrics. 2003 Jul;112(1 Pt 1):e46-54. Abstract

5. Guilleminault C, Fromherz S. Narcolepsy: diagnosis and management. In: Kryger MH, Roth T, Dement WC, eds. Principles and practice of sleep medicine. 4th ed. Philadelphia, PA: Elsevier Saunders; 2005.

6. Marcus CL, Trescher WH, Halbower AC, et al. Secondary narcolepsy in children with brain tumors. Sleep. 2002 Jun 15;25(4):435-9. Abstract

7. Spruyt K. Narcolepsy presentation in diverse populations: an update. Curr Sleep Med Rep. 2020;6(4):239-50.Full text  Abstract

8. Zeman A, Britton T, Douglas N, et al. Narcolepsy and excessive daytime sleepiness. BMJ. 2004 Sep 25;329(7468):724-8. Abstract

9. Acquavella J, Mehra R, Bron M, et al. Prevalence of narcolepsy and other sleep disorders and frequency of diagnostic tests from 2013-2016 in insured patients actively seeking care. J Clin Sleep Med. 2020 Aug 15;16(8):1255-63.Full text  Abstract

10. Tió E, Gaig C, Giner-Soriano M, et al. The prevalence of narcolepsy in Catalunya (Spain). J Sleep Res. 2018 Oct;27(5):e12640. Abstract

11. Müller S, Brandes A, Knierim J, et al. Epidemiology, diagnostics, and treatment of narcolepsy in Germany: the DORMIO study. J Sleep Med 2021 Aug 31;18(2):88-99.Full text

12. Wang Y, Chen Y, Tong Y, et al. Heterogeneity in estimates of incidence and prevalence of narcolepsy: a systematic review and meta-regression analysis. Neuroepidemiology. 2022;56(5):319-32.Full text  Abstract

13. Hublin C, Partinen M, Kaprio J, et al. Epidemiology of narcolepsy. Sleep. 1994 Dec;17(suppl 8):S7-12. Abstract

14. Silber MH, Krahn LE, Olson EJ, et al. The epidemiology of narcolepsy in Olmsted County, Minnesota: a population-based study. Sleep. 2002 Mar 15;25(2):197-202. Abstract

15. Ohayon MM, Priest RG, Zulley J, et al. Prevalence of narcolepsy symptomatology and diagnosis in the European general population. Neurology. 2002 Jun 25;58(12):1826-33. Abstract

16. Okun ML, Lin L, Pelin Z, et al. Clinical aspects of narcolepsy-cataplexy across ethnic groups. Sleep. 2002 Feb 1;25(1):27-35. Abstract

17. Ebrahim IO, Peacock KW, Williams AJ. Posttraumatic narcolepsy - two case reports and a mini review. J Clin Sleep Med. 2005 Apr 15;(2)1:153-6. Abstract

18. Silber MH. Narcolepsy, head injury, and the problem of causality. J Clin Sleep Med. 2005 Apr 15;1(2):157-8. Abstract

19. Bruck D, Broughton RJ. Diagnostic ambiguities in a case of post-traumatic narcolepsy with cataplexy. Brain Inj. 2004 Mar;18(3):321-6. Abstract

20. Scammell TE, Nishino S, Mignot E, et al. Narcolepsy and low CSF orexin (hypocretin) concentration after a diencephalic stroke. Neurology. 2001 Jun 26;56(12):1751-3. Abstract

21. Bjornstad B, Goodman SH, Sirven JI, et al. Paroxysmal sleep as a presenting symptom of bilateral paramedian thalamic infarctions. Mayo Clin Proc. 2003 Mar;78(3):347-9. Abstract

22. Rosenfeld MR, Eichen JG, Wade DF, et al. Molecular and clinical diversity in paraneoplastic immunity to Ma proteins. Ann Neurol. 2001 Sep;50(3):339-48. Abstract

23. Schwartz WJ, Stakes JW, Hobson JA. Transient cataplexy after removal of a craniopharyngioma. Neurology. 1984 Oct;34(10):1372-5. Abstract

24. Aldrich MS, Naylor MW. Narcolepsy associated with lesions of the diencephalon. Neurology. 1989 Nov;39(11):1505-8. Abstract

25. Arii J, Kanbayashi T, Tanabe Y, et al. A hypersomnolent girl with decreased CSF hypocretin level after removal of a hypothalamic tumor. Neurology. 2001 Jun 26;56(12):1775-6. Abstract

26. Malik S, Boeve BF, Krahn LE, et al. Narcolepsy associated with other central nervous system disorders. Neurology. 2001 Aug 14;57(3):539-41. Abstract

27. Gledhill RF, Bartel PR, Yoshida Y, et al. Narcolepsy caused by acute disseminated encephalomyelitis. Arch Neurol. 2004 May;61(5):758-60.Full text  Abstract

28. Rubinstein I, Gray TA, Moldofsky H, et al. Neurosarcoidosis associated with hypersomnolence treated with corticosteroids and brain irradiation. Chest. 1988 July;94(1):205-6. Abstract

29. Servan J, Marchand F, Garma L, et al. Narcolepsy disclosing neurosarcoidosis [in French]. Rev Neurol (Paris). 1995 Apr;151(4):281-3. Abstract

30. Clavelou P, Tournilhac M, Vidal C, et al. Narcolepsy associated with arteriovenous malformation of the diencephalon. Sleep. 1995 Apr;18(3):202-5. Abstract

31. Fleming WE, Pollak CP. Sleep disorders in multiple sclerosis. Semin Neurol. 2005 Mar;25(1):64-8. Abstract

32. Dalmau J, Graus F, Villarejo A, et al. Clinical analysis of anti-Ma2-associated encephalitis. Brain. 2004 Aug;127(pt 8):1831-44.Full text  Abstract

33. Landolfi JC, Nadkarni M. Paraneoplastic limbic encephalitis and possible narcolepsy in a patient with testicular cancer: case study. Neuro Oncol. 2003 Jul;5(3):214-6.Full text  Abstract

34. Overeem S, Dalmau J, Bataller L, et al. Hypocretin-1 CSF levels in anti-Ma2 associated encephalitis. Neurology. 2004 Jan 13;62(1):138-40. Abstract

35. Kandt RS, Emerson RG, Singer HS, et al. Cataplexy in variant forms of Niemann-Pick disease. Ann Neurol. 1982 Sept;12(3):284-8. Abstract

36. Vankova J, Stepanova I, Jech R, et al. Sleep disturbances and hypocretin deficiency in Niemann-Pick disease type C. Sleep. 2003 Jun 15;26(4):427-30.Full text  Abstract

37. Vossler DG, Wyler AR, Wilkus RJ, et al. Cataplexy and monoamine oxidase deficiency in Norrie disease. Neurology. 1996 May;46(5):1258-61. Abstract

38. Manni R, Politini L, Nobili L, et al. Hypersomnia in the Prader Willi syndrome: clinical-electrophysiological features and underlying factors. Clin Neurophysiol. 2001 May;112(5):800-5. Abstract

39. Hayduk R, Flodman P, Spence MA, et al. HLA haplotypes, polysomnography, and pedigrees in a case series of patients with narcolepsy. Sleep. 1997 Oct;20(10):850-7.Full text  Abstract

40. Taheri S, Mignot E. The genetics of sleep disorders. Lancet Neurol. 2002 Aug;1(4):242-50. Abstract

41. Tisdale RK, Yamanaka A, Kilduff TS. Animal models of narcolepsy and the hypocretin/orexin system: past, present, and future. Sleep. 2021 Jun 11;44(6):zsaa278.Full text  Abstract

42. Thannickal TC, Nienhuis R, Siegel JM. Localized loss of hypocretin (orexin) cells in narcolepsy without cataplexy. Sleep. 2009 Aug;32(8):993-8.Full text  Abstract

43. Cvetkovic-Lopes V, Bayer L, Dorsaz S, et al. Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients. J Clin Invest. 2010 Mar;120(3):713-9.Full text  Abstract

44. Kawashima M, Lin L, Tanaka S, et al. Anti-Tribbles homolog 2 (TRIB2) autoantibodies in narcolepsy are associated with recent onset of cataplexy. Sleep. 2010 Jul;33(7):869-74.Full text  Abstract

45. Lim AS, Scammell TE. The trouble with Tribbles: do antibodies against TRIB2 cause narcolepsy? Sleep. 2010 Jul;33(7):857-8.Full text  Abstract

46. Toyoda H, Tanaka S, Miyagawa T, et al. Anti-Tribbles homolog 2 autoantibodies in Japanese patients with narcolepsy. Sleep. 2010 Jul;33(7):875-8.Full text  Abstract

47. Aran A, Lin L, Nevsimalova S, et al. Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset. Sleep. 2009 Aug;32(8):979-83. Abstract

48. Longstreth WT Jr, Ton TG, Koepsell TD. Narcolepsy and streptococcal infections. Sleep. 2009 Dec;32(12):1548. Abstract

49. Okun ML, Giese S, Lin L, et al. Exploring the cytokine and endocrine involvement in narcolepsy. Brain Behav Immun. 2004 Jul;18(4):326-32. Abstract

50. Hohjoh H, Nakayama T, Ohashi J, et al. Significant association of a single nucleotide polymorphism in the tumor necrosis factor-alpha (TNF-alpha) gene promoter with human narcolepsy. Tissue Antigens. 1999 Aug;54(2):138-45. Abstract

51. Himmerich H, Beitinger PA, Fulda S, et al. Plasma levels of tumor necrosis factor alpha and soluble tumor necrosis factor receptors in patients with narcolepsy. Arch Intern Med. 2006 Sep 18;166(16):1739-43.Full text  Abstract

52. Hohjoh H, Terada N, Kawashima M, et al. Significant association of the tumor necrosis factor receptor 2 (TNFR2) gene with human narcolepsy. Tissue Antigens. 2000 Nov;56(5):446-8. Abstract

53. Dauvilliers Y, Carlander B, Rivier F, et al. Successful management of cataplexy with intravenous immunoglobulins at narcolepsy onset. Ann Neurol. 2004 Dec;56(6):905-8. Abstract

54. Dauvilliers Y, Abril B, Mas E, et al. Normalization of hypocretin-1 in narcolepsy after intravenous immunoglobulin treatment. Neurology. 2009 Oct 26;73(16):1333-4. Abstract

55. Hallmayer J, Faraco J, Lin L, et al. Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet. 2009 Jun;41(6):708-11. Abstract

56. Kornum BR, Kawashima M, Faraco J, et al. Common variants in P2RY11 are associated with narcolepsy. Nat Genet. 2011 Jan;43(1):66-71.Full text  Abstract

57. Han F, Faraco J, Dong XS, et al. Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. PLoS Genet. 2013 Oct;9(10):e1003880.Full text  Abstract

58. Nakayama J, Miura M, Honda M, et al. Linkage of human narcolepsy with HLA association to chromosome 4p13-q21. Genomics. 2000 Apr 1;65(1):84-6. Abstract

59. Miyagawa T, Hohjoh H, Honda Y, et al. Identification of a telomeric boundary of the HLA region with potential for predisposition to human narcolepsy. Immunogenetics. 2000 Nov;52(1-2):12-8. Abstract

60. Dauvilliers Y, Blouin JL, Neidhart E, et al. A narcolepsy susceptibility locus maps to a 5 Mb region of chromosome 21q. Ann Neurol. 2004 Sep;56(3):382-8. Abstract

61. Guilleminault C, Heinzer R, Mignot E, et al. Investigations into the neurologic basis of narcolepsy. Neurology. 1998 Feb;50(2 suppl 1):S8-15. Abstract

62. Faull KF, Thiemann S, King RJ, et al. Monoamine interactions in narcolepsy and hypersomnia: reanalysis. Sleep. 1989 Apr;12(2):185-6. Abstract

63. Faull KF, Barchas JD, Foutz AS, et al. Monoamine metabolite concentrations in the cerebrospinal fluid of normal and narcoleptic dogs. Brain Res. 1982 Jun 17;242(1):137-43. Abstract

64. Aldrich MS, Hollingsworth Z, Penney JB. Dopamine-receptor autoradiography of human narcoleptic brain. Neurology. 1992 Feb;42(2):410-5. Abstract

65. Nishino S, Sakurai E, Nevsimalova S, et al. Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls. Sleep. 2009 Feb;32(2):175-80.Full text  Abstract

66. Kanbayashi T, Kodama T, Kondo H, et al. CSF histamine contents in narcolepsy, idiopathic hypersomnia and obstructive sleep apnea syndrome. Sleep. 2009 Feb;32(2):181-7. Abstract

67. Fronczek R, Lammers GJ, Balesar R, et al. The number of hypothalamic hypocretin (orexin) neurons is not affected in Prader-Willi syndrome. J Clin Endocrinol Metab. 2005 Sep;90(9):5466-50.Full text  Abstract

68. Schüle B, Albalwi M, Northrop E, et al. Molecular breakpoint cloning and gene expression studies of a novel translocation t(4;15)(q27;q11.2) associated with Prader-Willi syndrome. BMC Med Genet. 2005 May 6;6:18.Full text  Abstract

69. Richdale AL, Cotton S, Hibbit K. Sleep and behaviour disturbance in Prader-Willi syndrome: a questionnaire study. J Intellect Disabil Res. 1999 Oct;43(pt 5):380-92. Abstract

70. Smit LS, Lammers GJ, Catsman-Berrevoets CE. Cataplexy leading to the diagnosis of Niemann-Pick disease type C. Pediatr Neurol. 2006 Jul;35(1):82-4. Abstract

71. Miyake S, Inoue H, Ohtahara S, et al. A case of Niemann-Pick disease type C with narcolepsy syndrome [in Japanese]. Rinsho Shinkeigaku. 1983 Jan;23(1):44-52. Abstract

72. Iwata T, Suzuki N, Mizuno H, et al. A marked decrease of orexin in the cerebrospinal fluid in a patient with myotonic dystrophy type 1 showing an excessive daytime sleepiness. [in Japanese]. Rinsho Shinkeigaku. 2009 Jul;49(7):437-9. Abstract

73. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991 Dec;14(6):540-5. Abstract

74. Johns MW. Reliability and factor analysis of the Epworth Sleepiness Scale. Sleep. 1992 Aug;15(4):376-81. Abstract

75. Chasens ER, Williams LL, Umlauf MG. Excessive sleepiness. In: Capezuti E, Zwicker D, Mezey M, et al, eds. Evidence-based geriatric nursing protocols for best practice. 3rd ed. New York, NY: Springer; 2009:459-76.

76. Broughton R, Dunham W, Newman J, et al. Ambulatory 24 hour sleep-wake monitoring in narcolepsy-cataplexy compared to matched controls. Electroencephalogr Clin Neurophysiol. 1988 Dec;70(6):473-81. Abstract

77. Dantz B, Edgar DM, Dement WC. Circadian rhythms in narcolepsy: studies on a 90 minute day. Electroencephalogr Clin Neurophysiol. 1994 Jan;90(1):24-35. Abstract

78. Guilleminault C, Gelb M. Clinical aspects and features of cataplexy. Adv Neurol. 1995;67:65-77. Abstract

79. Anic-Labat S, Guilleminault C, Kraemer HC, et al. Validation of a cataplexy questionnaire in 983 sleep-disorders patients. Sleep. 1999 Feb 1;22(1):77-87. Abstract

80. Howell M, Avidan AY, Foldvary-Schaefer N, et al. Management of REM sleep behavior disorder: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2023 Apr 1;19(4):759-68.Full text  Abstract

81. Golden EC, Lipford MC. Narcolepsy: Diagnosis and management. Cleve Clin J Med. 2018 Dec;85(12):959-69.Full text  Abstract

82. American Academy of Sleep Medicine. The AASM manual for scoring of sleep and associated events. Feb 2023 [internet publication].Full text

83. Littner M, Johnson SF, McCall WV, et al. Practice parameters for the treatment of narcolepsy: an update for 2000. Sleep. 2001 Jun 15;24(4):451-66. Abstract

84. Krahn LE, Arand DL, Avidan AY, et al. Recommended protocols for the Multiple Sleep Latency Test and Maintenance of Wakefulness Test in adults: guidance from the American Academy of Sleep Medicine. J Clin Sleep Med. 2021 Dec 1;17(12):2489-98.Full text  Abstract

85. Roehrs T, Roth T. Multiple sleep latency test: technical aspects and normal values. J Clin Neurophysiol. 1992 Jan;9(1):63-7. Abstract

86. Mignot E, Lin L, Finn L, et al. Correlates of sleep-onset REM periods during the multiple sleep latency test in community adults. Brain. 2006 Jun;129(Pt 6):1609-23.Full text  Abstract

87. Dauvilliers Y, Gosselin A, Paquet J, et al. Effect of age on MSLT results in patients with narcolepsy-cataplexy. Neurology. 2004 Jan 13;62(1):46-50. Abstract

88. Mignot E, Lammers GJ, Ripley B, et al. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch Neurol. 2002 Oct;59(10):1553-62.Full text  Abstract

89. Overeem S, Scammell TE, Lammers GJ. Hypocretin/orexin and sleep: implications for the pathophysiology and diagnosis of narcolepsy. Curr Opin Neurol. 2002 Dec;15(6):739-45. Abstract

90. Smith MT, McCrae CS, Cheung J, et al. Use of actigraphy for the evaluation of sleep disorders and circadian rhythm sleep-wake disorders: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2018 Jul 15;14(7):1231-7.Full text  Abstract

91. Chervin RD, Aldrich MS. Sleep onset REM periods during multiple sleep latency tests in patients evaluated for sleep apnea. Am J Respir Crit Care Med. 2000 Feb;161(2 Pt 1):426-31.Full text  Abstract

92. Maski K, Trotti LM, Kotagal S, et al. Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2021 Sep 1;17(9):1881-93.Full text  Abstract

93. Bassetti CLA, Kallweit U, Vignatelli L, et al. European guideline and expert statements on the management of narcolepsy in adults and children. Eur J Neurol. 2021 Sep;28(9):2815-30.Full text  Abstract

94. Maski K, Trotti LM, Kotagal S, et al. Treatment of central disorders of hypersomnolence: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment. J Clin Sleep Med. 2021 Sep 1;17(9):1895-945.Full text  Abstract

95. Goswami M. The influence of clinical symptoms on quality of life in patients with narcolepsy. Neurology. 1998 Feb;50(2 suppl 1):S31-6. Abstract

96. Dauvilliers Y, Bassetti C, Lammers GJ, et al. Pitolisant versus placebo or modafinil in patients with narcolepsy: a double-blind, randomised trial. Lancet Neurol. 2013 Nov;12(11):1068-75. Abstract

97. Romigi A, Vitrani G, Lo Giudice T, et al. Profile of pitolisant in the management of narcolepsy: design, development, and place in therapy. Drug Des Devel Ther. 2018 Aug 30;12:2665-75.Full text  Abstract

98. Lehert P, Falissard B. Multiple treatment comparison in narcolepsy: a network meta-analysis. Sleep. 2018 Dec 1;41(12):zsy185.Full text  Abstract

99. Davis CW, Kallweit U, Schwartz JC, et al. Efficacy of pitolisant in patients with high burden of narcolepsy symptoms: pooled analysis of short-term, placebo-controlled studies. Sleep Med. 2021 May;81:210-17.Full text  Abstract

100. Dauvilliers Y, Arnulf I, Szakacs Z, et al. Long-term use of pitolisant to treat patients with narcolepsy: Harmony III Study. Sleep. 2019 Oct 21;42(11):zsz174.Full text  Abstract

101. Xu XM, Wei YD, Liu Y, et al. Gamma-hydroxybutyrate (GHB) for narcolepsy in adults: an updated systematic review and meta-analysis. Sleep Med. 2019 Dec;64:62-70. Abstract

102. Kushida CA, Shapiro CM, Roth T, et al. Once-nightly sodium oxybate (FT218) demonstrated improvement of symptoms in a phase 3 randomized clinical trial in patients with narcolepsy. Sleep. 2022 Jun 13;45(6):zsab200.Full text  Abstract

103. Bogan RK, Thorpy MJ, Dauvilliers Y, et al. Efficacy and safety of calcium, magnesium, potassium, and sodium oxybates (lower-sodium oxybate [LXB]; JZP-258) in a placebo-controlled, double-blind, randomized withdrawal study in adults with narcolepsy with cataplexy. Sleep. 2021 Mar 12;44(3):zsaa206.Full text  Abstract

104. Thorpy MJ. Recently approved and upcoming treatments for narcolepsy. CNS Drugs. 2020 Jan;34(1):9-27.Full text  Abstract

105. Dauvilliers Y, Bogan RK, Šonka K, et al. Calcium, magnesium, potassium, and sodium oxybates oral solution: a lower-sodium alternative for cataplexy or excessive daytime sleepiness associated with narcolepsy. Nat Sci Sleep. 2022;14:531-46.Full text  Abstract

106. Thorpy MJ, Shapiro C, Mayer G, et al. A randomized study of solriamfetol for excessive sleepiness in narcolepsy. Ann Neurol. 2019 Mar;85(3):359-70.Full text  Abstract

107. Malhotra A, Shapiro C, Pepin JL. Long-term study of the safety and maintenance of efficacy of solriamfetol (JZP-110) in the treatment of excessive sleepiness in participants with narcolepsy or obstructive sleep apnea. Sleep. 2020 Feb 13;43(2):zsz220.Full text  Abstract

108. Szakacs Z, Dauvilliers Y, Mikhaylov V, et al. Safety and efficacy of pitolisant on cataplexy in patients with narcolepsy: a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2017 Mar;16(3):200-7. Abstract

109. Vignatelli L, D'Alessandro R, Candelise L. Antidepressant drugs for narcolepsy. Cochrane Database Syst Rev. 2008 Jan 23;(1):CD003724. Abstract

110. Avis KT, Shen J, Weaver P, et al. Psychosocial characteristics of children with central disorders of hypersomnolence versus matched healthy children. J Clin Sleep Med. 2015 Nov 15;11(11):1281-8.Full text  Abstract

111. Dauvilliers Y, Lecendreux M, Lammers GJ, et al. Safety and efficacy of pitolisant in children aged 6 years or older with narcolepsy with or without cataplexy: a double-blind, randomised, placebo-controlled trial. Lancet Neurol. 2023 Apr;22(4):303-11. Abstract

112. Weinhold SL, Seeck-Hirschner M, Nowak A, et al. The effect of intranasal orexin-A (hypocretin-1) on sleep, wakefulness and attention in narcolepsy with cataplexy. Behav Brain Res. 2014 Apr 1;262:8-13. Abstract

113. Huang YS, Guilleminault C. Narcolepsy: action of two gamma-aminobutyric acid type B agonists, baclofen and sodium oxybate. Pediatr Neurol. 2009 Jul;41(1):9-16. Abstract

114. Lee EK, Douglass AB. Baclofen for narcolepsy with cataplexy: two cases. Nat Sci Sleep. 2015 Jul 29;7:81-3.Full text  Abstract

115. Morse AM, Kelly-Pieper K, Kothare SV. Management of excessive daytime sleepiness in narcolepsy with baclofen. Pediatr Neurol. 2019 Apr;93:39-42. Abstract

116. Miyagawa T, Kawamura H, Obuchi M, et al. Effects of oral L-carnitine administration in narcolepsy patients: a randomized, double-blind, cross-over and placebo-controlled trial. PLoS One. 2013;8(1):e53707.Full text  Abstract

117. Swick TJ. Treatment paradigms for cataplexy in narcolepsy: past, present, and future. Nat Sci Sleep. 2015 Dec 11;7:159-69.Full text  Abstract

118. Roy A. Psychiatric aspects of narcolepsy. Br J Psychiatry. 1976 Jun;128:562-5. Abstract

119. Mitler MM, Aldrich MS, Koob GF, et al. Narcolepsy and its treatment with stimulants. ASDA standards of practice. Sleep. 1994 Jun;17(4):352-71. Abstract

120. Boivin DB, Montplaisir J, Petit D, et al. Effects of modafinil on symptomatology of human narcolepsy. Clin Neuropharmacol. 1993 Feb;16(1):46-53. Abstract

121. Miller MM, Hajdukovic R, Erman MK. Treatment of narcolepsy with methamphetamine. Sleep. 1993 Jun;16(4):306-17.Full text  Abstract

122. Arand D, Bonnet M, Hurwitz T, et al. The clinical use of the MSLT and MWT. Sleep. 2005 Jan;28(1):123-44. Abstract