Last reviewed: September 2018
Last updated: July  2018

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • abdominal bloating
  • fatigue
  • breast tenderness
  • headaches
  • depressed mood, irritability, and internal tension
  • labile mood
  • adverse effect on life

Other diagnostic factors

  • increased appetite
  • forgetfulness and difficulty concentrating
  • other subjective symptoms
  • insomnia or hypersomnia
  • gastrointestinal upset
  • heart palpitations
  • hot flushes

Risk factors

  • post-pubescent and premenopausal women
  • family history
  • mood disorders
  • cigarette smoking
  • white women
  • sexual abuse and/or trauma

Diagnostic investigations

Investigations to consider

  • thyroid function tests
  • follicle-stimulating hormone levels
  • depression screening
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Editor in Chief

Maturitas

President

European Menopause and Andropause Society

Reader Emeritus in Reproductive Medicine

University of Oxford

Women's Centre, John Radcliffe Hospital

Oxford

Visiting Professor

Faculty of Medicine

University of Glasgow

Glasgow

UK

Adjunct Associate Professor

Robert Wood Johnson Medical School

Rutgers University

New Brunswick

NJ

Disclosures

MR declares that she has no competing interests.

Associate Professor

Department of Obstetrics, Gynecology and Reproductive Sciences

Rutgers Robert Wood Johnson Medical School

New Brunswick

NJ

Disclosures

NAP declares that she has no competing interests.

Professor

Department of Obstetrics, Gynecology and Reproductive Sciences

Rutgers Robert Wood Johnson Medical School

New Brunswick

NJ

Disclosures

GB declares that she has no competing interests.

Professor Margaret Rees, Dr Nancy A. Phillips, and Dr Gloria Bachmann would like to gratefully acknowledge Dr Desiree Lie, the previous contributor to this topic. DL declares that she has no competing interests.

Peer reviewers VIEW ALL

Obstetrician-Gynecologist

Department of Obstetrics and Gynecology

University of California Irvine Medical Center

Orange

CA

Disclosures

JT declares that she has no competing interests.

Consultant in Perinatal Mental Health

Liverpool Women's NHS Foundation Trust

Liverpool

UK

Disclosures

CH declares that she has no competing interests.

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