Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- pain (anterior uveitis)
- decreased vision
- synechiae
- flare
- keratic precipitates
Outros fatores diagnósticos
- tearing
- photophobia
- floaters
- eye redness without discharge
- constricted or nonreactive pupil
- decreased intraocular pressure
- retinal exudates and edema, optic nerve edema
- retinal vascular sheathing
- macular edema
- optic disk swelling
- retinal hemorrhages
- ciliary flush
- corneal edema
- cataract
Fatores de risco
- inflammatory diseases of the joints, bowel, or skin
- human leukocyte antigen (HLA)-B27 positive
- ocular trauma
- age 30 to 40 years
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- clinical diagnosis
Investigações a serem consideradas
- CBC
- erythrocyte sedimentation rate (ESR)
- CRP
- fluorescent treponemal antibody (FTA-ABS), Venereal Disease Research Laboratory (VDRL), and rapid plasma reagin (RPR)
- serum ACE
- antinuclear antibodies
- HLA-B27
- Lyme titer
- purified protein derivative (PPD) skin test
- cytoplasmic anti-neutrophil cytoplasmic antibodies (c-ANCA)
- perinuclear anti-neutrophil cytoplasmic antibodies (p-ANCA)
- anti-double-stranded DNA antibody (anti-dsDNA)
- rheumatoid factor
- anti-cyclic citrullinated peptide (anti-CCP) antibodies
- Bartonella henselae titer
- toxoplasma serologic titer
- other HLA antigens
- biochemistry screen
- CXR
- polymerase chain reaction (PCR)
Novos exames
- vitreous biopsy
Algoritmo de tratamento
noninfectious, initial presentation: not pregnant
noninfectious, initial presentation: pregnant
infectious
noninfectious, after immediate control of inflammation: not pregnant
noninfectious, after immediate control of inflammation: pregnant
Colaboradores
Autores
John J. Huang, MD
President
Connecticut Uveitis Foundation
Associate Clinical Professor
Yale University
New Haven
New England Retina Associates
Hamden
CT
Declarações
JJH declares that he has no competing interests.
Maxwell Elia, MD
Uveitis and Retina Specialist
Medical Eye Center of New Hampshire
Manchester
NH
Declarações
ME declares that he has no competing interests.
Agradecimentos
Dr John J. Huang and Dr Maxwell Elia would like to gratefully acknowledge Dr Richard Gale, Dr Zsolt Varga, Dr Victor L. Perez, and Dr Carlos A. Medina, the previous contributors to this topic.
Declarações
RG, ZV, VLP, and CAM declare that they have no competing interests.
Revisores
Jessica Ackert, MD
Assistant Professor
Ophthalmology
Mount Sinai Hospital
New York
NY
Declarações
JA declares that she has no competing interests.
Anthony J. Hall, MD, FRANZCO
Director of Ophthalmology
Alfred Hospital
Melbourne
Australia
Declarações
AJH has been reimbursed by Novartis, the manufacturer of Lucentis, for lecture fees. AJH's employer, the Alfred Hospital, has received research funding from Novartis, the manufacturer of Lucentis, and from Bayer, the manufacturer of Eylea.
Daniel A. Johnson, MD
Chairman
Department of Ophthalmology
The University of Texas Health Science Center at San Antonio
San Antonio
TX
Declarações
DAJ declares that he has no competing interests.
Referências
Principais artigos
Deschenes J, Murray PI, Rao NA, et al; International Uveitis Study Group. International Uveitis Study Group (IUSG): clinical classification of uveitis. Ocul Immunol Inflamm. 2008 Jan-Feb;16(1):1-2. Resumo
Jabs DA, Nussenblatt RD, Rosenbaum JT; Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop. Am J Ophthalmol. 2005 Sep;140(3):509-16. Resumo
Kempen JH, Altaweel MM, Holbrook JT, et al; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Randomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: the multicenter uveitis steroid treatment trial. Ophthalmology. 2011 Oct;118(10):1916-26.Texto completo Resumo
Artigos de referência
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