Mortality in patients who develop ARDS is 30% to 50%.[35][117] Death is most often due to multiple organ failure rather than purely to respiratory failure.[118] Low tidal volume ventilation reduced in-hospital mortality from 40% to 31% in the 2000 ARDS Network trial.[57] Being of a younger age may also increase the chances of survival.[119] Patients who do survive their illness usually have some residual decrease in lung function, although it may not always cause symptoms.[120][121] Muscle weakness, neuropathies, joint disorders, and chronic pain are also common in survivors of ARDS at 1 year.[122]

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