A presumptive diagnosis of GS is made when a patient exhibits the following findings:
Repeated unconjugated hyperbilirubinaemia
No evidence of haemolysis, with normal findings on complete blood count, reticulocyte count, Coombs' test, and blood smear
Normal LFTs except for the bilirubin
Exclusion of other disease processes.
If the above findings continue to be present, a definitive diagnosis may be reported after 3 to 12 months of follow-up. Confirmatory tests may be performed in the case of any diagnostic doubt.
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