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Toxic thyroid adenoma

  • Обзор
  • Теория
  • Диагноз
  • Лечение
  • Последующее наблюдение
  • Источники
Последний просмотренный: 12 Aug 2025
Last updated: 01 Oct 2024

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • palpable thyroid nodule
  • younger age
Полная информация

Другие диагностические факторы

  • hyperphagia
  • weight loss
  • sweating/heat intolerance
  • nervousness
  • palpitations
  • oligomenorrhea
  • hyperdefecation
  • dyspnea
  • stare or lid lag
  • tachycardia
  • tremor
  • warm moist skin
  • muscle weakness
  • hoarseness
  • dysphagia
  • choking
  • mood change
Полная информация

Факторы риска

  • young adult age
  • iodine deficiency
  • head and neck irradiation
  • family history of thyroid nodules
  • female sex
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • thyroid stimulating hormone (TSH)
Полная информация

Исследования, проведение которых нужно рассмотреть

  • free thyroxine (T4; or total T4 with a measure of binding)
  • total T3 with a measure of binding (or free T3)
  • thyroid scan and uptake
  • thyroid ultrasound
  • metabolic panel
  • CBC
  • TSH receptor antibodies
  • thyroid peroxidase antibodies
  • ECG
  • CT neck (noncontrast)
Полная информация

Алгоритм лечения

ПРОДОЛЖЕНИЕ

nonpregnant nonlactating adults without mass effect

nonpregnant nonlactating adults with mass effect

pregnant or lactating

Составители

Авторы

Elizabeth N. Pearce, MD

Professor of Medicine

Boston University Medical Center

Boston

MA

Раскрытие информации

ENP is a member of the Management Council of the Iodine Global Network. She was the 2018-2019 President of the American Thyroid Association (ATA) and served on its board and executive committee until 2020. She is a current member of the ATA's thyroid in pregnancy guidelines writing task force. She is currently a Deputy Editor at the Journal of Clinical Endocrinology and Metabolism and has previously served as an Associated Editor for the journals Thyroid, Endocrine Practice, and Clinical Thyroidology. She is an author of a number of references cited in this topic.

Выражение благодарностей

Dr Elizabeth N. Pearce would like to gratefully acknowledge Dr Sheila Feit, the previous contributor to this topic.

Рецензенты

John C. Morris, MD

Professor of Medicine

Mayo Clinic

Rochester

MN

Раскрытие информации

JCM declares that he has no competing interests.

Petros Perros, BSc, MBBS, MD, FRCP

Consultant Endocrinologist

Freeman Hospital

Newcastle-Upon-Tyne

UK

Раскрытие информации

PP declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

Ross DS, Burch HB, Cooper DS, et al. 2016 American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis. Thyroid. 2016 Oct;26(10):1343-421.Полный текст  Аннотация

Gharib H, Papini E, Garber JR, et al. American Association of Clinical Endocrinologists, American College of Endocrinology, and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules - 2016 update. Endocr Pract. 2016 May;22(5):622-39.Полный текст  Аннотация

Haugen BR, Alexander EK, Bible KC, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. Thyroid. 2016 Jan;26(1):1-133.Полный текст  Аннотация

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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