Accidental hypothermia

References

Key articles

Dow J, Giesbrecht GG, Danzl DF, et al. Wilderness Medical Society clinical practice guidelines for the out-of-hospital evaluation and treatment of accidental hypothermia: 2019 update. Wilderness Environ Med. 2019 Dec;30(4 Suppl):S47-69.Full text  Abstract

Lott C, Truhlář A, Alfonzo A, et al. European Resuscitation Council Guidelines 2021: Cardiac arrest in special circumstances. Resuscitation. 2021 Apr;161:152-219.Full text  Abstract

Reference articles

1. American College of Surgeons. Advanced Trauma Life Support student course manual, 10th edition. Chicago, IL: American College of Surgeons; 2018.

2. Jurkovich GJ, Greiser WB, Luterman A, et al. Hypothermia in trauma victims: an ominous predictor of survival. J Trauma. 1987 Sep;27(9):1019-24. Abstract

3. Paal P, Gordon L, Strapazzon G, et al. Accidental hypothermia - an update. Scand J Trauma Resusc Emerg Med. 2016 Sep 15;24(1):111.Full text  Abstract

4. Dow J, Giesbrecht GG, Danzl DF, et al. Wilderness Medical Society clinical practice guidelines for the out-of-hospital evaluation and treatment of accidental hypothermia: 2019 update. Wilderness Environ Med. 2019 Dec;30(4 Suppl):S47-69.Full text  Abstract

5. Mallet ML. Pathophysiology of accidental hypothermia. QJM. 2002 Dec;95(12):775-85.Full text  Abstract

6. Pasquier M, Zurron N, Weith B, et al. Deep accidental hypothermia with core temperature below 24°C presenting with vital signs. High Alt Med Biol. 2014 Apr;15(1):58-63. Abstract

7. Rollstin AD, Seifert SA. Acetaminophen/diphenhydramine overdose in profound hypothermia. Clin Toxicol (Phila). 2013 Jan;51(1):50-3. Abstract

8. MacDonell JE, Wrenn K. Hypothermia in the summer. South Med J. 1991 Jun;84(6):804-5. Abstract

9. Burke WP. A case report of warm weather accidental hypothermia. J Miss State Med Assoc. 2004 Sep;45(9):263-6. Abstract

10. Brown DJ, Brugger H, Boyd J, et al. Accidental hypothermia. N Engl J Med. 2012 Nov 15;367(20):1930-8. Abstract

11. Jolly BT, Ghezzi KT. Accidental hypothermia. Emerg Med Clin North Am. 1992 May;10(2):311-27. Abstract

12. Krantz MJ, Lowery CM. Images in clinical medicine. Giant Osborn waves in hypothermia. N Engl J Med. 2005 Jan 13;352(2):184. Abstract

13. Darocha T, Sobczyk D, Kosiński S, et al. Electrocardiographic changes caused by severe accidental hypothermia. J Cardiothorac Vasc Anesth. 2015 Dec;29(6):e83-6.Full text  Abstract

14. Severinghaus JW, Stupfel MA, Bradley AF. Alveolar, dead space, and arterial to end tidal carbon dioxide differences during hypothermia in dog and man. J Appl Physiol. 1957 May;10(3):349-55. Abstract

15. Sterba JA. Efficacy and safety of prehospital rewarming techniques to treat accidental hypothermia. Ann Emerg Med. 1991 Aug;20(8):896-901. Abstract

16. Scott EM, Buckland R. A systematic review of intraoperative warming to prevent postoperative complications. AORN J. 2006 May;83(5):1090-1104, 1107-13. Abstract

17. Leslie K, Sessler DI. Perioperative hypothermia in the high-risk surgical patient. Best Pract Res Clin Anaesthesiol. 2003 Dec;17(4):485-98. Abstract

18. Horn EP, Bein B, Böhm R, et al. The effect of short time periods of pre-operative warming in the prevention of peri-operative hypothermia. Anaesthesia. 2012 Jun;67(6):612-7. Abstract

19. National Institute for Health and Care Exellence. Hypothermia: prevention and management in adults having surgery. December 2016 [internet publication].Full text

20. Avellanas ML, Ricart A, Botella J, et al. [Management of severe accidental hypothermia]. [in spa]. Med Intensiva. 2012 Apr;36(3):200-12.Full text  Abstract

21. Giesbrecht GG. Cold stress, near drowning and accidental hypothermia: a review. Aviat Space Environ Med. 2000 Jul;71(7):733-52. Abstract

22. Hwang SW, Lebow JM, Bierer MF, et al. Risk factors for death in homeless adults in Boston. Arch Intern Med. 1998 Jul 13;158(13):1454-60.Full text  Abstract

23. Golden FS, Hervey GR, Tipton MJ. Circum-rescue collapse: collapse, sometimes fatal, associated with rescue of immersion victims. J R Nav Med Serv. 1991 Winter;77(3):139-49. Abstract

24. Lott C, Truhlář A, Alfonzo A, et al. European Resuscitation Council Guidelines 2021: Cardiac arrest in special circumstances. Resuscitation. 2021 Apr;161:152-219.Full text  Abstract

25. Foggle JL. Accidental hypothermia: 'you're not dead until you're warm and dead'. R I Med J (2013). 2019 Feb 1;102(1):28-32. Abstract

26. National Institute for Health and Care Excellence. Major trauma: assessment and initial management. February 2016 [internet publication].Full text

27. Urdang MS, Shoenberger JM, Triamarit P, et al. ECG analysis in accidental urban hypothermia. Paper presented at: ACEP Research Forum 2009. Abstract 446. Ann Emerg Med. 2009 Sep;54(3 Suppl):S141.Full text

28. Urdang M, Shoenberger JM, Triamarit P, et al. ECG analysis in accidental urban hypothermia. J Emerg Med. 2009 August;37(2):235.

29. Gale EA, Bennett T, Green JH, et al. Hypoglycaemia, hypothermia and shivering in man. Clin Sci (Lond). 1981 Oct;61(4):463-9. Abstract

30. Darocha T, Kosiński S, Jarosz A, et al. Should capnography be used as a guide for choosing a ventilation strategy in circulatory shock caused by severe hypothermia? Observational case-series study. Scand J Trauma Resusc Emerg Med. 2017 Feb 15;25(1):15.Full text  Abstract

31. Breen EG, Coghlan JG, Egan E, et al. Impaired coagulation in accidental hypothermia of the elderly. Age Ageing. 1988 Sep;17(5):343-6. Abstract

32. Weinberg AD. Hypothermia. Ann Emerg Med. 1993 Feb;22(2 Pt 2):370-77. Abstract

33. Schaller MD, Fischer AP, Perret CH. Hyperkalemia. A prognostic factor during acute severe hypothermia. JAMA. 1990 Oct 10;264(14):1842-5. Abstract

34. Brugger H, Durrer B, Elsensohn F, et al. Resuscitation of avalanche victims: evidence-based guidelines of the International Commission for Mountain Emergency Medicine (ICAR MEDCOM): intended for physicians and other advanced life support personnel. Resuscitation. 2013 May;84(5):539-46.Full text  Abstract

35. Panchal AR, Bartos JA, Cabañas JG, et al. Part 3: adult basic and advanced life support: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2020 Oct 20;142(16 suppl 2):S366-S468.Full text  Abstract

36. O'Driscoll BR, Howard LS, Earis J, et al. BTS guideline for oxygen use in adults in healthcare and emergency settings. Thorax. 2017 Jun;72(suppl 1):ii1-ii90.Full text  Abstract

37. Danzl DF, Pozos RS. Accidental hypothermia. N Engl J Med. 1994 Dec 29;331(26):1756-60. Abstract

38. European Resuscitation Council. The European Resuscitation Council guidelines for resuscitation 2015. Oct 2015 [internet publication].Full text

39. Gentilello LM. Advances in the management of hypothermia. Surg Clin North Am. 1995 Apr;75(2):243-56. Abstract

40. Vretenar DF, Urschel JD, Parrott JC, et al. Cardiopulmonary bypass resuscitation for accidental hypothermia. Ann Thorac Surg. 1994 Sep;58(3):895-8. Abstract

41. Walpoth BH, Walpoth-Aslan BN, Mattle HP, et al. Outcome of survivors of accidental deep hypothermia and circulatory arrest treated with extracorporeal blood warming. N Engl J Med. 1997 Nov 20;337(21):1500-5. Abstract

42. Austin MA, Maynes EJ, O'Malley TJ, et al. Outcomes of extracorporeal life support use in accidental hypothermia: a systematic review. Ann Thorac Surg. 2020 Dec;110(6):1926-32. Abstract

43. Dunne B, Christou E, Duff O, et al. Extracorporeal-assisted rewarming in the management of accidental deep hypothermic cardiac arrest: a systematic review of the literature. Heart Lung Circ. 2014 Nov;23(11):1029-35. Abstract

44. Dépret F, Peacock WF, Liu KD, et al. Management of hyperkalemia in the acutely ill patient. Ann Intensive Care. 2019 Feb 28;9(1):32.Full text  Abstract

45. Hughes A, Riou P, Day C. Full neurological recovery from profound (18.0 degrees C) acute accidental hypothermia: successful resuscitation using active invasive rewarming techniques. Emerg Med J. 2007 Jul;24(7):511-2. Abstract

46. O'Driscoll BR, Howard LS, Earis J, et al; British Thoracic Society Emergency Oxygen Guideline Group; BTS Emergency Oxygen Guideline Development Group. BTS guideline for oxygen use in adults in healthcare and emergency settings. Thorax. 2017 Jun;72(suppl 1):ii1-90 Abstract

47. NHS England. Toolkit for general practice in supporting older people living with frailty. March 2017 [internet publication]Full text

48. Wallis SJ, Wall J, Biram RW, et al. Association of the clinical frailty scale with hospital outcomes. QJM. 2015 Dec;108(12):943-9Full text  Abstract

49. Quinn TJ, Mooijaart SP, Gallacher K, et al. Acute care assessment of older adults living with frailty. BMJ. 2019 Jan 31;364:l13 Abstract

50. Royal College of Physicians. National early warning score (NEWS2). Standardising the assessment of acute-illness severity in the NHS. December 2017 [internet publication]Full text

51. Global Initiative for Asthma. Global strategy for asthma management and prevention. 2022 [internet publication]Full text

52. British Thoracic Society; Scottish Intercollegiate Guidelines Network. British guideline on the management of asthma: a national clinical guideline. July 2019 [internet publication].Full text

53. Chu DK, Kim LH, Young PJ, et al. Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): systematic review and meta-analysis. Lancet. 2018 Apr 26;391(10131):1693-705 Abstract

54. Siemieniuk RAC, Chu DK, Kim LH, et al. Oxygen therapy for acutely ill medical patients: a clinical practice guideline. BMJ. 2018 Oct 24;363:k4169Full text  Abstract

55. National Institute for Health and Care Excellence. Intravenous fluid therapy in adults in hospital. Clinical guideline CG174. May 2017 [internet publication]Full text

56. Verbrugge FH, Grieten L, Mullens W. Management of the cardiorenal syndrome in decompensated heart failure. Cardiorenal Med. 2014 Dec;4(3-4):176-88Full text  Abstract

57. National Institute for Health and Care Excellence. Acute kidney injury: prevention, detection and management. December 2019 [internet publication]Full text

58. Hsu CY, Ordoñez JD, Chertow GM, et al. The risk of acute renal failure in patients with chronic kidney disease. Kidney Int. 2008 Apr 2;74(1):101-7Full text  Abstract

59. Hogervorst VM, Buurman BM, De Jonghe A, et al. Emergency department management of older people living with frailty: a guide for emergency practitioners. Emerg Med J. 2021 Sep;38(9):724-9 Abstract

60. Rockwood K; British Geriatrics Society. Silver book II: frailty. February 2021 [internet publication]Full text

61. Royal College of Physicians. Acute care toolkit 3. Acute care for older people living with frailty. December 2020 [internet publication]Full text

62. Conroy SP, Bardsley M, Smith P, et al. Comprehensive geriatric assessment for frail older people in acute hospitals: the HoW-CGA mixed-methods study. Health Services and Delivery Research. 2019 April:7(15)Full text

63. Lott C, Truhlář A, Alfonzo A, et al. European Resuscitation Council Guidelines 2021: Cardiac arrest in special circumstances. Resuscitation. 2021 Apr;161:152-219Full text  Abstract

64. Golden FS, Hervey GR, Tipton MJ. Circum-rescue collapse: collapse, sometimes fatal, associated with rescue of immersion victims. J R Nav Med Serv. 1991 Winter;77(3):139-49 Abstract

65. Zonnenberg C, Bueno-de-Mesquita JM, Ramlal D, et al. Hypothermia due to antipsychotic medication: a systematic review. Front Psychiatry. 2017;8:165Full text  Abstract

66. Fritz Z, Slowther AM, Perkins GD. Resuscitation policy should focus on the patient, not the decision. BMJ. 2017 Feb 28;356:j813Full text  Abstract

67. The National Institute for Health and Care Excellence. Decision making and mental capacity. October 2018 [internet publication]Full text

68. Office of the Public Guardian. Mental Capacity Act: making decisions. October 2014 [internet publiction]Full text

69. Social Care Institute for Excellence. Independent mental capacity advocate (IMCA). January 2010 [internet publication]Full text

70. Gale EA, Tattersall RB. Hypothermia: a complication of diabetic ketoacidosis. Br Med J. 1978 Nov 18;2(6149):1387-9Full text  Abstract

71. Chowdhury TA, Cheston H, Claydon A. Managing adults with diabetes in hospital during an acute illness. BMJ. 2017 Jun 22;357:j2551 Abstract

72. Joint British Diabetes Societies for Inpatient Care. Self-management of diabetes in hospital. Feb 2023 [internet publication].Full text

73. Joint British Diabetes Societies for Inpatient Care. The use of variable rate intravenous insulin infusion (VRIII) in medical inpatients. Oct 2014 [internet publication].Full text

74. Joint British Diabetes Societies for Inpatient Care. A good inpatient diabetes service. Jul 2019 [internet publication].Full text

75. Centre for Perioperative Care. Guideline for perioperative care for people with diabetes mellitus undergoing elective and emergency surgery. Dec 2022 [internet publication].Full text

76. Pasquel FJ, Lansang MC, Dhatariya K, et al. Management of diabetes and hyperglycaemia in the hospital. Lancet Diabetes Endocrinol. 2021 Mar;9(3):174-88Full text  Abstract

77. Medicines and Healthcare products Regulatory Agency. SGLT2 inhibitors: monitor ketones in blood during treatment interruption for surgical procedures or acute serious medical illness. March 2020 [internet publication]Full text

78. Peters AL, Buschur EO, Buse JB, et al. Euglycemic diabetic ketoacidosis: a potential complication of treatment with sodium-glucose cotransporter 2 inhibition. Diabetes Care. 2015 Jun 15;38(9):1687-93 Abstract

79. Joint British Diabetes Societies for Inpatient Care. The management of diabetic ketoacidosis in adults. Mar 2023 [internet publication].Full text

80. Grau AJ, Urbanek C, Palm F. Common infections and the risk of stroke. Nat Rev Neurol. 2010 Nov 9;6(12):681-94 Abstract

81. Eigenbrodt ML, Rose KM, Couper DJ, et al. Orthostatic hypotension as a risk factor for stroke: the atherosclerosis risk in communities (ARIC) study, 1987-1996. Stroke. 2000 Oct;31(10):2307-13 Abstract

82. Winstein CJ, Stein J, Arena R, et al. Guidelines for adult stroke rehabilitation and recovery: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2016 May 4;47(6):e98-e169Full text  Abstract

83. Pendlebury ST, Klaus SP, Mather M, et al. Routine cognitive screening in older patients admitted to acute medicine: abbreviated mental test score (AMTS) and subjective memory complaint versus Montreal Cognitive Assessment and IQCODE. Age Ageing. 2015 Oct 13;44(6):1000-5Full text  Abstract

84. Hodkinson HM. Evaluation of a mental test score for assessment of mental impairment in the elderly. Age Ageing. 1972 Nov;1(4):233-8 Abstract

85. National Institute for Health and Care Excellence. Delirium: prevention, diagnosis and management in hospital and long-term care. Jan 2023 [internet publication].Full text

86. National Institute for Health and Care Excellence. Dementia: assessment, management and support for people living with dementia and their carers. Jun 2018 [internet publication].Full text

87. Scottish Intercollegiate Guidelines Network. Risk reduction and management of delirium. Mar 2019 [internet publication].Full text

88. Nova Scotia Health Authority. This is not my Mom. 2012 [internet publication]Full text

89. Inouye SK, Schlesinger MJ, Lydon TJ. Delirium: a symptom of how hospital care is failing older persons and a window to improve quality of hospital care. Am J Med. 1999 May;106(5):565-73 Abstract

90. Bellelli G, Morandi A, Davis DH, et al. Validation of the 4AT, a new instrument for rapid delirium screening: a study in 234 hospitalised older people. Age Ageing. 2014 Mar 2;43(4):496-502Full text  Abstract

91. MacLullich AM, Shenkin SD, Goodacre S, et al. The 4 'A's test for detecting delirium in acute medical patients: a diagnostic accuracy study. Health Technol Assess. 2019 Aug;23(40):1-194Full text  Abstract

92. White S, Griffiths R, Baxter M, et al. Guidelines for the peri-operative care of people with dementia: guidelines from the Association of Anaesthetists. Anaesthesia. 2019 Jan 11;74(3):357-72Full text  Abstract

93. Siddiqi N, Harrison JK, Clegg A, et al. Interventions for preventing delirium in hospitalised non-ICU patients. Cochrane Database Syst Rev. 2016 Mar 11;3:CD005563Full text  Abstract

94. Martinez F, Tobar C, Hill N. Preventing delirium: should non-pharmacological, multicomponent interventions be used? A systematic review and meta-analysis of the literature. Age Ageing. 2014 Nov 25;44(2):196-204Full text  Abstract

95. Public Health England. Urinary tract infection: diagnostic tools for primary care. October 2020 [internet publication]Full text

96. Medicines and Healthcare products Regulatory Agency. Haloperidol (haldol): reminder of risks when used in elderly patients for the acute treatment of delirium. 2021 [internet publication]Full text

97. Ma H, Huang Y, Cong Z, et al. The efficacy and safety of atypical antipsychotics for the treatment of dementia: a meta-analysis of randomized placebo-controlled trials. J Alzheimers Dis. 2014;42(3):915-37 Abstract

98. Huybrechts KF, Gerhard T, Crystal S, et al. Differential risk of death in older residents in nursing homes prescribed specific antipsychotic drugs: population based cohort study. BMJ. 2012 Feb 23;344:e977Full text  Abstract

99. Van Leeuwen E, Petrovic M, van Driel ML, et al. Withdrawal versus continuation of long-term antipsychotic drug use for behavioural and psychological symptoms in older people with dementia. Cochrane Database Syst Rev. 2018 Mar 30;3:CD007726Full text  Abstract

100. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13 Abstract

101. Boden JM, Fergusson DM. Alcohol and depression. Addiction. 2011 Mar 7;106(5):906-14 Abstract

102. National Institute for Health and Care Excellence. Liaison psychiatry. In: Emergency acute medical care in over 16s: service delivery and organisation. March 2018 [internet publication]Full text

103. National Confidential Enquiry into Patient Outcome and Death (NCEPOD). Treat as one. Bridging the gap between mental and physical healthcare in general hospitals. 2017 [internet publication]Full text

104. DiMatteo MR, Lepper HS, Croghan TW. Depression is a risk factor for noncompliance with medical treatment: meta-analysis of the effects of anxiety and depression on patient adherence. Arch Intern Med. 2000 Jul 24;160(14):2101-7 Abstract

105. Clarke DM, Currie KC. Depression, anxiety and their relationship with chronic diseases: a review of the epidemiology, risk and treatment evidence. Med J Aust. 2009 Apr 6;190(7 suppl):S54-60 Abstract

106. National Institute for Health and Care Excellence. Depression in adults with a chronic physical health problem: recognition and management. October 2009 [internet publication]Full text

107. Prina AM, Cosco TD, Dening T, et al. The association between depressive symptoms in the community, non-psychiatric hospital admission and hospital outcomes: a systematic review. J Psychosom Res. 2014 Nov 8;78(1):25-33Full text  Abstract

108. World Health Organization. Excess mortality in persons with severe mental disorders. 2016 [internet publication]Full text

109. Cleare A, Pariante CM, Young AH, et al. Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2008 British Association for Psychopharmacology guidelines. J Psychopharmacol. 2015 May 12;29(5):459-525Full text  Abstract

110. National Institute for Health and Care Excellence. Depression in adults with a chronic physical health problem: recognition and management. 2009 [internet publication]Full text

111. Taylor DM, Barnes TRE, Young AH. The Maudsley prescribing guidelines in psychiatry. 14th edition. Chichester: Wiley-Blackwell; 2021

112. Boyer EW, Shannon M. The serotonin syndrome. N Engl J Med. 2005 Mar 17;352(11):1112-20 Abstract

113. Buckley NA, Dawson AH, Isbister GK. Serotonin syndrome. BMJ. 2014 Feb 19;348:g1626 Abstract

114. Dalton SO, Sørensen HT, Johansen C. SSRIs and upper gastrointestinal bleeding: what is known and how should it influence prescribing? CNS Drugs. 2006;20(2):143-51 Abstract

115. Dalton SO, Johansen C, Mellemkjaer L, et al. Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal tract bleeding: a population-based cohort study. Arch Intern Med. 2003 Jan 13;163(1):59-64Full text  Abstract

116. Cheng YL, Hu HY, Lin XH, et al. Use of SSRI, but not SNRI, increased upper and lower gastrointestinal bleeding: a nationwide population-based cohort study in Taiwan. Medicine (Baltimore). 2015 Nov;94(46):e2022Full text  Abstract

117. Loke YK, Trivedi AN, Singh S. Meta-analysis: gastrointestinal bleeding due to interaction between selective serotonin uptake inhibitors and non-steroidal anti-inflammatory drugs. Aliment Pharmacol Ther. 2008 Jan 1;27(1):31-40Full text  Abstract

118. Flowers L. Nicotine replacement therapy. Am J Psychiatry Resid. 2016 Jun;11(6)4-7Full text

119. Desai HD, Seabolt J, Jann MW. Smoking in patients receiving psychotropic medications: a pharmacokinetic perspective. CNS Drugs. 2001;15(6):469-94 Abstract

120. Oliveira P, Ribeiro J, Donato H, Madeira N. Smoking and antidepressants pharmacokinetics: a systematic review. Ann Gen Psychiatry. 2017;16:17Full text  Abstract

121. National Centre for Smoking Cessation and Training. Smoking cessation and mental health. 2014 [internet publication]Full text

122. ElSayed NA, Aleppo G, Aroda VR, et al, on behalf of the American Diabetes Association. 16. Diabetes care in the hospital: standards of care in diabetes - 2023. Diabetes Care. 2023 Jan 1;46(suppl 1):S267-78.Full text  Abstract

123. National Institute for Health and Care Excellence. Type 1 diabetes in adults: diagnosis and management. Aug 2022 [internet publication].Full text

124. Joint British Diabetes Societies for Inpatient Care. Inpatient care of the frail older adult with diabetes. Feb 2023 [internet publication].Full text

125. van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically ill patients. N Engl J Med. 2001 Nov 8;345(19):1359-67Full text  Abstract

126. NICE-SUGAR Study Investigators; Finfer S, Chittock DR, Su SY, et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009 Mar 26;360(13):1283-97.Full text  Abstract

127. Marik PE, Preiser JC. Toward understanding tight glycemic control in the ICU: a systematic review and metaanalysis. Chest. 2010 Mar;137(3):544-51Full text  Abstract

128. Joint British Diabetes Societies for Inpatient Care. The management of the hyperosmolar hyperglycaemic state (HHS) in adults. Feb 2022 [internet publication].Full text

129. Rehman A, Setter SM, Vue MH. Drug-induced glucose alterations part 2: drug-Induced hyperglycemia. Diabetes Spect. 2011 Nov;24(4):234-8Full text

130. NHS Digital. National Diabetes Inpatient Audit (NaDIA) - 2019. Nov 2020 [internet publication]Full text

131. Joint British Diabetes Societies for Inpatient Care. The hospital management of hypoglycaemia in adults with diabetes mellitus. Jan 2023 [internet publication].Full text

132. TREND Diabetes. End of life guidance for diabetes care. November 2021 [internet publication]Full text

133. National Institute for Health and Care Excellence. Diabetic foot problems: prevention and management. October 2019 [internet publication]Full text

134. Rayman G, Vas PR, Baker N, et al. The Ipswich Touch Test: a simple and novel method to identify inpatients with diabetes at risk of foot ulceration. Diabetes Care. 2011 May 18;34(7):1517-8Full text  Abstract

135. Salpeter SR, Ormiston TM, Salpeter EE. Cardiovascular effects of beta-agonists in patients with asthma and COPD: a meta-analysis. Chest. 2004 Jun;125(6):2309-21Full text  Abstract

136. Au DH, Curtis JR, Every NR, et al. Association between inhaled beta-agonists and the risk of unstable angina and myocardial infarction. Chest. 2002 Mar;121(3):846-51Full text  Abstract

137. Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease. 2023 [internet publication]Full text

138. Walters JA, Tan DJ, White CJ, et al. Different durations of corticosteroid therapy for exacerbations of chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2018 Mar 19;3:CD006897Full text  Abstract

139. National Institute for Health and Care Excellence. Chronic obstructive pulmonary disease in over 16s: diagnosis and management. July 2019 [internet publication]Full text

140. National Institute for Health and Care Excellence. Tobacco: preventing uptake, promoting quitting and treating dependence. Jan 2023 [internet publication].Full text

141. Lindson N, Chepkin SC, Ye W, et al. Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation. Cochrane Database Syst Rev. 2019 Apr 18;4(4):CD013308.Full text  Abstract

142. Rigotti NA, Kruse GR, Livingstone-Banks J, et al. Treatment of tobacco smoking: a review. JAMA. 2022 Feb 8;327(6):566-77.Full text  Abstract

143. Thomas KH, Dalili MN, López-López JA, et al. Comparative clinical effectiveness and safety of tobacco cessation pharmacotherapies and electronic cigarettes: a systematic review and network meta-analysis of randomized controlled trials. Addiction. 2022 Apr;117(4):861-76.Full text  Abstract

144. Splittgerber FH, Talbert JG, Sweezer WP, et al. Partial cardiopulmonary bypass for core rewarming in profound accidental hypothermia. Am Surg. 1986 Aug;52(8):407-12. Abstract

145. Centers for Disease Control and Prevention (CDC). Heat-related illnesses and deaths - United States, 1994-1995. MMWR Morb Mortal Wkly Rep. 1995 Jun 30;44(25):465-8.Full text  Abstract

146. White J. Hypothermia: the Bellevue experience. Ann Emerg Med. 1982 Aug;11(8):417-24. Abstract

147. Kurtz KJ. Hypothermia in the elderly: the cold facts. Geriatrics. 1982 Jan;37(1):85-93. Abstract

148. Vassal T, Benoit-Gonin B, Carrat F, et al. Severe accidental hypothermia treated in an ICU: prognosis and outcome. Chest. 2001 Dec;120(6):1998-2003. Abstract

149. Ward MM. Factors predictive of acute renal failure in rhabdomyolysis. Arch Intern Med. 1988 Jul;148(7):1553-7. Abstract

150. Reuler JB. Hypothermia: pathophysiology, clinical settings, and management. Ann Intern Med. 1978 Oct;89(4):519-27. Abstract

151. Foulis AK. Morphological study of the relation between accidental hypothermia and acute pancreatitis. J Clin Pathol. 1982 Nov;35(11):1244-8.Full text  Abstract

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