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Septic arthritis

最后审阅: 17 Aug 2025
最后更新: 15 Oct 2024

小结

定义

病史和体格检查

关键诊断因素

  • hot, swollen, tender, restricted joint
完整详情

其他诊断因素

  • low socioeconomic status
  • history of intravenous drug abuse
  • history of diabetes
  • history of cutaneous ulcers
  • prosthetic joint
  • history of rheumatoid arthritis or osteoarthritis
  • short history of symptoms
  • fever
  • history of alcohol use disorder
  • history of previous corticosteroid injection
完整详情

危险因素

  • underlying joint disease
  • joint prostheses
  • immunosuppression
  • contiguous spread (presence of cutaneous ulcers or skin infection)
  • previous intra-articular corticosteroid injection
  • recent joint surgery
完整详情

诊断性检查

首要检查

  • synovial fluid Gram stain and culture
  • synovial fluid white cell count
  • blood culture
  • white cell count
  • erythrocyte sedimentation rate
  • CRP
  • plain radiograph
  • ultrasound
完整详情

需考虑的检查

  • procalcitonin
  • MRI
完整详情

治疗流程

初步治疗

suspected gram-positive infection or negative Gram stain

suspected gram-negative infection

急症处理

confirmed MSSA or streptococcal infection

confirmed MRSA infection

confirmed gram-negative rods infection

confirmed gonococcal or meningococcal infection

infection with fungi/tuberculosis/other organisms

撰稿人

作者

Gerald Coakley, PhD, FRCP
Gerald Coakley

Consultant Rheumatologist

Queen Elizabeth Hospital

London

UK

გაფრთხილება:

GC is an author of a reference cited in this topic.

Catherine J. Mathews, MSc, FRCP
Catherine J. Mathews

Consultant Rheumatologist

Queen Elizabeth Hospital

London

UK

გაფრთხილება:

CJM is an author of a reference cited in this topic.

რეცენზენტები

Andrew Keat, MBBS

Consultant Physician and Rheumatologist

Northwick Park Hospital

Harrow

UK

Declarações

AK declares that he has no competing interests.

Cheryl Main, MD, FRCPC

Medical Microbiologist

Infectious Disease Consultant

Hamilton Regional Laboratory Medicine Program

Hamilton Health Sciences

Hamilton

Canada

Declarações

CM declares that she has no competing interests.

John Ross, MD

Brigham and Women’s Hospital

Hospitalist Section

Boston

MA

Declarações

JR declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

Ross JJ. Septic arthritis of native joints. Infect Dis Clin North Am. 2017 Jun;31(2):203-18. Resumo

Earwood JS, Walker TR, Sue GJC. Septic arthritis: diagnosis and treatment. Am Fam Physician. 2021 Dec 1;104(6):589-97.Texto completo  Resumo

Coakley G, Mathews C, Field M, et al. BSR and BHPR, BOA, RCGP and BSAC guidelines for management of the hot swollen joint in adults. Rheumatology (Oxford). 2006 Aug;45(8):1039-41.Texto completo  Resumo

Mathews CJ, Coakley G; British Society for Rheumatology. Hot joint update 2017. Mar 2017 [internet publication].Texto completo

American College of Radiology. ACR appropriateness criteria: suspected osteomyelitis, septic arthritis, or soft tissue infection (excluding spine and diabetic foot). 2022 [internet publication].Texto completo

Artigos de referência

Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
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