Diverticular disease


Key articles

National Institute for Health and Care Excellence. Diverticular disease: diagnosis and management. November 2019 [internet publication].Full text

Sartelli M, Weber DG, Kluger Y, et al. 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World J Emerg Surg. 2020 May 7;15(1):32.Full text  Abstract

Peery AF. Management of colonic diverticulitis. BMJ. 2021 Mar 24;372:n72.Full text  Abstract

Reference articles

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31. Wess L, Eastwood MA, Wess TJ, et al. Cross linking of collagen is increased in colonic diverticulosis. Gut. 1995 Jul;37(1):91-4. Abstract

32. Painter NS, Burkitt DP. Diverticular disease of the colon, a 20th century problem. Clin Gastroenterol. 1975 Jan;4(1):3-21. Abstract

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34. Ma W, Nguyen LH, Song M, et al. Intake of dietary fiber, fruits, and vegetables and risk of diverticulitis. Am J Gastroenterol. 2019 Sep;114(9):1531-8.Full text  Abstract

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38. National Institute for Health and Care Excellence. Diverticular disease: diagnosis and management. November 2019 [internet publication].Full text

39. Sugihara Y, Kudo SE, Miyachi H, et al. Analysis of risk factors for colonic diverticular bleeding: a matched case-control study. Gut Liver. 2016 Mar;10(2):244-9.Full text  Abstract

40. Yuhara H, Corley DA, Nakahara F, et al. Aspirin and non-aspirin NSAIDs increase risk of colonic diverticular bleeding: a systematic review and meta-analysis. J Gastroenterol. 2014 Jun;49(6):992-1000. Abstract

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46. Sartelli M, Weber DG, Kluger Y, et al. 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World J Emerg Surg. 2020 May 7;15(1):32.Full text  Abstract

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50. Peery AF. Management of colonic diverticulitis. BMJ. 2021 Mar 24;372:n72.Full text  Abstract

51. Jensen DM, Machicado GA, Jutabha R, et al. Urgent colonoscopy for the diagnosis and treatment of severe diverticular hemorrhage. N Eng J Med. 2000 Jan 13;342(2):78-82. Abstract

52. Strate LL, Gralnek IM. ACG clinical guideline: management of patients with acute lower gastrointestinal bleeding. Am J Gastroenterol. 2016 Apr;111(4):459-74.Full text  Abstract

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59. Biondo S, Golda T, Kreisler E, et al. Outpatient versus hospitalization management for uncomplicated diverticulitis: a prospective, multicenter randomized clinical trial (DIVER trial). Ann Surg. 2014 Jan;259(1):38-44. Abstract

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61. Byrnes MC, Mazuski JE. Antimicrobial therapy for acute colonic diverticulitis. Surg Infect (Larchmt). 2009Apr;10(2):143-54. Abstract

62. Eberhardt F, Crichton M, Dahl C, et al. Role of dietary fibre in older adults with asymptomatic (AS) or symptomatic uncomplicated diverticular disease (SUDD): systematic review and meta-analysis. Maturitas. 2019 Dec;130:57-67. Abstract

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67. Chabok A, Påhlman L, Hjern F, et al. Randomized clinical trial of antibiotics in acute uncomplicated diverticulitis. Br J Surg. 2012 Apr;99(4):532-9. Abstract

68. Daniels L, Ünlü Ç, de Korte N, et al. Randomized clinical trial of observational versus antibiotic treatment for a first episode of CT-proven uncomplicated acute diverticulitis. Br J Surg. 2017 Jan;104(1):52-61. Abstract

69. Peery AF, Shaukat A, Strate LL. AGA clinical practice update on medical management of colonic diverticulitis: expert review. Gastroenterology. 2021 Feb;160(3):906-11.Full text  Abstract

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71. Desai M, Fathallah J, Nutalapati V, et al. Antibiotics versus no antibiotics for acute uncomplicated diverticulitis: a systematic review and meta-analysis. Dis Colon Rectum. 2019 Aug;62(8):1005-12. Abstract

72. Emile SH, Elfeki H, Sakr A, et al. Management of acute uncomplicated diverticulitis without antibiotics: a systematic review, meta-analysis, and meta-regression of predictors of treatment failure. Tech Coloproctol. 2018 Jul;22(7):499-509. Abstract

73. Oakland K, Guy R, Uberoi R, et al. Acute lower GI bleeding in the UK: patient characteristics, interventions and outcomes in the first nationwide audit. Gut. 2018 Apr;67(4):654-62. Abstract

74. Oakland K, Jairath V, Uberoi R, et al. Derivation and validation of a novel risk score for safe discharge after acute lower gastrointestinal bleeding: a modelling study. Lancet Gastroenterol Hepatol. 2017 Sep;2(9):635-43. Abstract

75. Bloomfeld RS, Rockey DC, Shetzline MA. Endoscopic therapy of acute diverticular hemorrhage. Am J Gastroenterol. 2001 Aug;96(8):2367-72. Abstract

76. Angenete E, Bock D, Rosenberg J, et al. Laparoscopic lavage is superior to colon resection for perforated purulent diverticulitis-a meta-analysis. Int J Colorectal Dis. 2017 Feb;32(2):163-9.Full text  Abstract

77. Cirocchi R, Di Saverio S, Weber DG, et al. Laparoscopic lavage versus surgical resection for acute diverticulitis with generalised peritonitis: a systematic review and meta-analysis. Tech Coloproctol. 2017 Feb;21(2):93-110. Abstract

78. Gregersen R, Mortensen LQ, Burcharth J, et al. Treatment of patients with acute colonic diverticulitis complicated by abscess formation: a systematic review. Int J Surg. 2016 Nov;35:201-8. Abstract

79. Toorenvliet BR, Swank H, Schoones JW, et al. Laparoscopic peritoneal lavage for perforated colonic diverticulitis: a systematic review. Colorectal Dis. 2010 Sep;12(9):862-7. Abstract

80. Angenete E, Thornell A, Burcharth J, et al. Laparoscopic lavage is feasible and safe for the treatment of perforated diverticulitis with purulent peritonitis: the first results from the randomized controlled trial DILALA. Annf Surg. 2016 Jan;263(1):117-22.Full text  Abstract

81. Gehrman J, Angenete E, Björholt I, et al. Health economic analysis of laparoscopic lavage versus Hartmann's procedure for diverticulitis in the randomized DILALA trial. Br J Surg. 2016 Oct;103(11):1539-47.Full text  Abstract

82. Schultz JK, Wallon C, Blecic L, et al. One-year results of the SCANDIV randomized clinical trial of laparoscopic lavage versus primary resection for acute perforated diverticulitis. Br J Surg. 2017 Sep;104(10):1382-92. Abstract

83. Shaikh FM, Stewart PM, Walsh SR, et al. Laparoscopic peritoneal lavage or surgical resection for acute perforated sigmoid diverticulitis: a systematic review and meta-analysis. Int J Surg. 2017 Feb;38:130-7. Abstract

84. Galbraith N, Carter JV, Netz U, et al. Laparoscopic lavage in the management of perforated diverticulitis: a contemporary meta-analysis. J Gastrointest Surg. 2017 Sep;21(9):1491-9. Abstract

85. Abbas S. Resection and primary anastomosis in acute complicated diverticulitis, a systematic review of the literature. Int J Colorectal Dis. 2007 Apr;22(4):351-7. Abstract

86. Janes S, Meagher A, Faragher IG, et al. The place of elective surgery following acute diverticulitis in young patients: when is surgery indicated? An analysis of the literature. Dis Colon Rectum. 2009 May;52(5):1008-16. Abstract

87. Richards RJ, Hammitt JK. Timing of prophylactic surgery in prevention of diverticulitis recurrence: a cost-effectiveness analysis. Dig Dis Sci. 2002 Sep;47(9):1903-8. Abstract

88. Siddiqui MR, Sajid MS, Qureshi S, et al. Elective laparoscopic sigmoid resection for diverticular disease has fewer complications than conventional surgery: a meta-analysis. Am J Surg. 2010 Jul;200(1):144-61. Abstract

89. Cirocchi RF, Farinella E, Trastulli S, et al. Elective sigmoid colectomy for diverticular disease. Laparoscopic vs open surgery: a systematic review. Colorectal Dis. 2012 Jun;14(6):671-83. Abstract

90. Andeweg CS, Berg R, Staal JB, et al. Patient-reported outcomes after conservative or surgical management of recurrent and chronic complaints of diverticulitis: systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2016 Feb;14(2):183-90. Abstract

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