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Interstitial cystitis (bladder pain syndrome)

最后审阅: 20 八月 2025
最后更新: 09 二月 2023

小结

定义

病史和体格检查

关键诊断因素

  • presence of risk factors
  • food or stress triggers
  • urinary urgency
  • urinary frequency
  • urinary incontinence
  • nocturia
  • dysuria
  • pelvic-floor pain
  • dyspareunia
  • worsening of symptoms before menses
  • urethral pain
  • bladder neck pain
  • suprapubic pain
  • levator ani pain
  • pain after placement of Foley's catheter
完整详情

其他诊断因素

  • fibromyalgia
  • vulvar vestibulitis
  • vulvodynia
  • features of systemic lupus erythematosus
  • migraine
  • features of rheumatoid arthritis
  • features of chronic fatigue syndrome
  • allergies
  • sexual/domestic abuse
  • scrotal or anal pain
完整详情

危险因素

  • age 20 to 60 years
  • female sex
  • positive family history
  • sexual or domestic abuse
  • white ethnicity
完整详情

诊断性检查

首要检查

  • urinalysis with microscopy and culture
  • vaginal wet prep
  • voiding diary
  • urine cytology
完整详情

需考虑的检查

  • cystoscopy with hydro-distension of bladder
  • bladder biopsy
完整详情

新兴检查

  • stress protein gene assay
  • urine anti-proliferative factor
  • urine nerve growth factor (NGF)

治疗流程

持续性治疗

non-ulcerative interstitial cystitis

ulcerative interstitial cystitis

撰稿人

作者

Kenneth M. Peters, MD

Professor and Chairman

Department of Urology

Oakland University William Beaumont School of Medicine

Chair

Department of Urology

Beaumont Health System

Royal Oak

MI

利益声明

KMP declares that he has no competing interests.

Hailey Eisner​, DO

Fellow, FPMRS Urology

Oakland University William Beaumont School of Medicine

Auburn Hills

MI

利益声明

HE declares that she has no competing interests.

Priya Padmanabhan, MD, MPH

Professor of Urology

Oakland University William Beaumont School of Medicine

Auburn Hills

MI

利益声明

PP declares that she has no competing interests.

鸣谢

Dr Kenneth M. Peters, Dr Hailey Eisner, and Dr Priya Padmanabhan would like to gratefully acknowledge Dr Lauren Tennyson, Dr Natalie Gaines, Dr Serge P. Marinkovic, Dr Robert Moldwin, Dr Stuart L. Stanton, Dr Lisa M. Gillen, Dr Christina Marinkovic, and Dr Michael Ehlert, the previous contributors to this topic.

利益声明

LT, NG, SPM, RM, SLS, LMG, CM, and ME declare that they have no competing interests.

同行评议者

Nissrine Nakib, MD

Assistant Professor

Director of Female Urology and Urodynamics

University of Minnesota

Minneapolis

MN

利益声明

NN declares that she has no competing interests.

Neil Baum, MD

Urologist

Touro Medical Office

New Orleans

LA

Declarações

NB declares that he has no competing interests.

Charles Butrick, MD

Director

The Urogynecology Center

Overland Park

KS

Declarações

CB declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

Clemens JQ, Erickson DR, Varela NP et al. Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment. J Urol. 2022 July;208(1):34-42.Texto completo

Engeler D, Baranowski AP, Berghmans B, et al. European Association of Urology. Guidelines on chronic pelvic pain. 2022 [internet publication].Texto completo

van de Merwe JP, Nordling J, Bouchelouche P, et al. Diagnostic criteria, classification, and nomenclature for painful bladder syndrome/interstitial cystitis: an ESSIC proposal. Eur Urol. 2008 Jan;53(1):60-7. Resumo

Cox A, Golda N, Nadeau G, et al. CUA guideline: diagnosis and treatment of interstitial cystitis/bladder pain syndrome. Can Urol Assoc J. 2016 May-Jun;10(5-6):E136-55.Texto completo  Resumo

Imamura M, Scott NW, Wallace SA, et al. Interventions for treating people with symptoms of bladder pain syndrome: a network meta-analysis. Cochrane Database Syst Rev. 2020 Jul 30;7(7):CD013325.Texto completo  Resumo

Artigos de referência

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