小结
定义
病史和体格检查
关键诊断因素
- presence of risk factors
- food or stress triggers
- urinary urgency
- urinary frequency
- urinary incontinence
- nocturia
- dysuria
- pelvic-floor pain
- dyspareunia
- worsening of symptoms before menses
- urethral pain
- bladder neck pain
- suprapubic pain
- levator ani pain
- pain after placement of Foley's catheter
其他诊断因素
- fibromyalgia
- vulvar vestibulitis
- vulvodynia
- features of systemic lupus erythematosus
- migraine
- features of rheumatoid arthritis
- features of chronic fatigue syndrome
- allergies
- sexual/domestic abuse
- scrotal or anal pain
危险因素
- age 20 to 60 years
- female sex
- positive family history
- sexual or domestic abuse
- white ethnicity
诊断性检查
首要检查
- urinalysis with microscopy and culture
- vaginal wet prep
- voiding diary
- urine cytology
需考虑的检查
- cystoscopy with hydro-distension of bladder
- bladder biopsy
新兴检查
- stress protein gene assay
- urine anti-proliferative factor
- urine nerve growth factor (NGF)
治疗流程
non-ulcerative interstitial cystitis
ulcerative interstitial cystitis
撰稿人
作者
Kenneth M. Peters, MD
Professor and Chairman
Department of Urology
Oakland University William Beaumont School of Medicine
Chair
Department of Urology
Beaumont Health System
Royal Oak
MI
利益声明
KMP declares that he has no competing interests.
Hailey Eisner, DO
Fellow, FPMRS Urology
Oakland University William Beaumont School of Medicine
Auburn Hills
MI
利益声明
HE declares that she has no competing interests.
Priya Padmanabhan, MD, MPH
Professor of Urology
Oakland University William Beaumont School of Medicine
Auburn Hills
MI
利益声明
PP declares that she has no competing interests.
鸣谢
Dr Kenneth M. Peters, Dr Hailey Eisner, and Dr Priya Padmanabhan would like to gratefully acknowledge Dr Lauren Tennyson, Dr Natalie Gaines, Dr Serge P. Marinkovic, Dr Robert Moldwin, Dr Stuart L. Stanton, Dr Lisa M. Gillen, Dr Christina Marinkovic, and Dr Michael Ehlert, the previous contributors to this topic.
利益声明
LT, NG, SPM, RM, SLS, LMG, CM, and ME declare that they have no competing interests.
同行评议者
Nissrine Nakib, MD
Assistant Professor
Director of Female Urology and Urodynamics
University of Minnesota
Minneapolis
MN
利益声明
NN declares that she has no competing interests.
Neil Baum, MD
Urologist
Touro Medical Office
New Orleans
LA
Declarações
NB declares that he has no competing interests.
Charles Butrick, MD
Director
The Urogynecology Center
Overland Park
KS
Declarações
CB declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Referências
Principais artigos
Clemens JQ, Erickson DR, Varela NP et al. Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment. J Urol. 2022 July;208(1):34-42.Texto completo
Engeler D, Baranowski AP, Berghmans B, et al. European Association of Urology. Guidelines on chronic pelvic pain. 2022 [internet publication].Texto completo
van de Merwe JP, Nordling J, Bouchelouche P, et al. Diagnostic criteria, classification, and nomenclature for painful bladder syndrome/interstitial cystitis: an ESSIC proposal. Eur Urol. 2008 Jan;53(1):60-7. Resumo
Cox A, Golda N, Nadeau G, et al. CUA guideline: diagnosis and treatment of interstitial cystitis/bladder pain syndrome. Can Urol Assoc J. 2016 May-Jun;10(5-6):E136-55.Texto completo Resumo
Imamura M, Scott NW, Wallace SA, et al. Interventions for treating people with symptoms of bladder pain syndrome: a network meta-analysis. Cochrane Database Syst Rev. 2020 Jul 30;7(7):CD013325.Texto completo Resumo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
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