Routine screening is not recommended for type 1 diabetes due to a low population prevalence. Screening for antibodies that confer high risk is also not recommended because animal and human studies have not confirmed the utility of treatment (e.g., with nicotinamide; or oral, parenteral, or nasal insulin) to prevent or delay type 1 diabetes in high-risk individuals. Screening for related antibodies is only recommended in the context of a clinical research study.[48]

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