Approach

Myasthenia gravis (MG) most commonly affects young adult women (under 40 years) and older men (over 60 years), but it can occur at any age.

Following a review of the patient's medical history and typical examination findings, the diagnosis of MG can be established by clinical and serological testing. If serological testing is unremarkable, clinical neurophysiological testing should be performed. Pulmonary function tests can help predict whether respiration is impaired, and so avoid myasthenic crisis.

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