Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- storage symptoms
- voiding symptoms
Risk factors
- age over 50 years
- family history
- non-Asian race
- cigarette smoking
- male pattern baldness
- metabolic syndrome
Diagnostic investigations
1st investigations to order
- urinalysis
- prostate-specific antigen (PSA)
- International Prostate Symptom Score
- global bother score
- volume charting
Investigations to consider
- ultrasound
- CT abdomen/pelvis
- cystoscopy
- uroflowmetry
- urodynamic study
Treatment algorithm
Contributors
Authors

Professor
Internal Medicine
University of South Florida College of Medicine
Department of Internal Medicine
Tampa
FL
Disclosures
MTF declares that he has no competing interests.
Associate Professor and Program Director
Internal Medicine
University of South Florida College of Medicine
Department of Internal Medicine
Tampa
FL
Disclosures
EA declares that she has no competing interests.
Peer reviewers
Consultant Urological Surgeon
Royal Hallamshire Hospital
Honorary Senior Lecturer of Urology
University of Sheffield
Newcastle University
Visiting Professor of Urology
Sheffield Hallam University
Adjunct Secretary responsible for Education
European Association of Urology
Sheffield
UK
Disclosures
CRC is Chairman of NICE Male LUTS Guidelines Development Group.
Professor of Urology
Institute of Cellular Medicine
Newcastle University
Newcastle upon Tyne
UK
Disclosures
RP has received funding from the UK NHS (NIHR) to undertake commissioned reviews of treatment for benign prostatic enlargement.
Chief
Department of Surgery
South Seminole Hospital
Longwood
FL
Disclosures
SKB is a member of the National Speakers Bureau for Boehringer Ingelheim, Astellas Pharmaceutics, and Glaxo Pharmaceuticals and has served as a consultant for these companies.
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