Amfetamine use disorder

Amfetamines have certain therapeutic uses, but misuse potential is high.

No medication has proven effective in breaking the misuse cycle.

Aggressive psychological and sociological interventions are needed to reduce the high recidivism rate.

Amfetamine use disorder involves the recreational use (other than for an approved medical indication) of a class of non-catecholamine sympathomimetic amines - specifically, amfetamines, metamfetamines, and 3,4-methylenedioxymethamfetamine (MDMA, also known as ecstasy), misused by oral and intravenous routes, nasal insufflation (snorting) and inhalation (smoking), resulting in either acute or chronic toxicity. Although these compounds have been used to improve alertness, enhance performance, reduce appetite, and improve concentration in attention deficit disorders, the misuse potential is high.