Cocaine abuse can lead to several psychosocial and psychological sequelae including family disruption, work impairment, financial ruin, violent behaviour, extreme mood states, and paranoia. Chronic use can also lead to poor health due to adverse cardiac effects. Cocaine intoxication symptoms may bring a patient to seek medical attention. Illegal drug activities may additionally bring those transporting cocaine by sequestration (swallowing packets of cocaine, known as body packing) to the attention of medical personnel. The increased use of contaminated cocaine (possibly done to potentiate the effects of cocaine) with levamisole may cause agranulocytosis and other haematological disorders, skin necrosis, and symptoms consistent with pulmonary hypertension.
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