Alcohol use disorder

References

Key articles

American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., text revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.

Reus VI, Fochtmann LJ, Bukstein O, et al. The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder. Am J Psychiatry. 2018 Jan 1;175(1):86-90.Full text  Abstract

Lingford-Hughes AR, Welch S, Peter L, et al. BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction, and comorbidity: recommendations from BAP. J Psychopharmacol. 2012 Jul;26(7):899-952. Abstract

Anton RF, O'Malley SS, Ciraulo DA, et al. Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA. 2006 May 3;295(17):2003-17.Full text  Abstract

Reference articles

1. National Institute on Alcohol Abuse and Alcoholism. Drinking levels defined [internet publication].Full text

2. Kelly JF, Westerhoff CM. Does it matter how we refer to individuals with substance-related conditions? A randomized study of two commonly used terms. Int J Drug Policy. 2010 May;21(3):202-7. Abstract

3. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th ed., text revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.

4. World Health Organization. International classification of diseases​ 11th revision (ICD-11). Jan 2022 [internet publication].Full text

5. Allen JP. Use of biomarkers of heavy drinking in health care practice. Mil Med. 2003 May;168(5):364-7. Abstract

6. World Health Organization.​ Global status report on alcohol and health 2018. September 2018 [internet publication].Full text

7. Grant BF, Goldstein RB, Saha TD, et al. Epidemiology of DSM-5 alcohol use disorder: results from the national epidemiologic survey on alcohol and related conditions III. JAMA Psychiatry. 2015 Aug;72(8):757-66.Full text  Abstract

8. Kanny D, Naimi TS, Liu Y, et al. Annual total binge drinks consumed by US Adults, 2015. Am J Prev Med. 2018 Apr;54(4):486-96. Abstract

9. Spillane S, Shiels MS, Best AF, et al. Trends in alcohol-induced deaths in the United States, 2000-2016. JAMA Netw Open. 2020 Feb 5;3(2):e1921451.Full text  Abstract

10. Pollard MS, Tucker JS, Green HD Jr. Changes in adult alcohol use and consequences during the COVID-19 pandemic in the US. JAMA Netw Open. 2020 Sep 1;3(9):e2022942.Full text  Abstract

11. GBD 2016 Alcohol Collaborators. Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2018 Sep 22;392(10152):1015-35.Full text  Abstract

12. Swift RM. Drug therapy for alcohol dependence. N Engl J Med. 1999 May 13;340(19):1482-90. Abstract

13. Addolorato G, Leggio L, Abenavoli L, et al. Neurobiochemical and clinical aspects of craving in alcohol addiction: a review. Addict Behav. 2005 Jul;30(6):1209-24. Abstract

14. Tawa EA, Hall SD, Lohoff FW. Overview of the genetics of alcohol use disorder. Alcohol Alcohol. 2016 Sep;51(5):507-14.Full text  Abstract

15. Koob GF, Volkow ND. Neurobiology of addiction: a neurocircuitry analysis. Lancet Psychiatry. 2016 Aug;3(8):760-73. Abstract

16. Plunk AD, Syed-Mohammed H, Cavazos-Rehg P, et al. Alcohol consumption, heavy drinking, and mortality: rethinking the j-shaped curve. Alcohol Clin Exp Res. 2014 Feb;38(2):471-8. Abstract

17. Leggio L, Kenna GA, Swift RM. New developments for the pharmacological treatment of alcohol withdrawal syndrome: a focus on non-benzodiazepine GABAergic medications. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1106-17. Abstract

18. Malcolm RJ. GABA systems, benzodiazepines, and substance dependence. J Clin Psychiatry. 2003;64(suppl 3):36-40. Abstract

19. Gordis E. Alcohol research: at the cutting edge. Arch Gen Psychiatry. 1996 Mar;53(3):199-201. Abstract

20. Cloninger CR, Bohman M, Sigvardsson S. Inheritance of alcohol abuse: cross-fostering analysis of adopted men. Arch Gen Psychiatry. 1981 Aug;38(8):861-8. Abstract

21. Babor TF, Dolinsky ZS, Meyer RE, et al. Types of alcoholics: concurrent and predictive validity of some common classification schemes. Br J Addict. 1992 Oct;87(10):1415-31. Abstract

22. Leggio L, Addolorato G. Serotonin transporter (SERT) brain density and neurobiological cloninger subtypes model: a lesson by human autoradiography studies. Alcohol Alcohol. 2008 Mar-Apr;43(2):148-50. Abstract

23. Poikolainen K. Risk factors for alcohol dependence: a case-control study. Alcohol Alcohol. 2000 Mar-Apr;35(2):190-6. Abstract

24. Ward RJ, McPherson AJS, Chow C, et al. Identification and characterization of alcohol-induced flushing in Caucasian subjects. Alcohol Alcohol. 1994 Jul;29(4):433-8. Abstract

25. Schuckit MA, Hesselbrock V, Tipp J, et al. A comparison of DSM-III-R, DSM-IV and ICD-10 substance use disorders diagnoses in 1922 men and women subjects in the COGA study. Addiction. 1994 Dec;89(12):1629-38. Abstract

26. Svensson PA, Anveden Å, Romeo S, et al. Alcohol consumption and alcohol problems after bariatric surgery in the Swedish obese subjects study. Obesity (Silver Spring). 2013 Dec;21(12):2444-51.Full text  Abstract

27. Toomey TL, Wagenaar AC. Policy options for prevention: the case of alcohol. J Public Health Policy. 1999;20(2):192-213. Abstract

28. Anderson P, Chisholm D, Fuhr DC. Effectiveness and cost-effectiveness of policies and programmes to reduce the harm caused by alcohol. Lancet. 2009 Jun 27;373(9682):2234-46. Abstract

29. Smit E, Verdurmen J, Monshouwer K, et al. Family interventions and their effect on adolescent alcohol use in general populations; a meta-analysis of randomized controlled trials. Drug Alcohol Depend. 2008 Oct 1;97(3):195-206. Abstract

30. Donoghue K, Patton R, Phillips T, et al. The effectiveness of electronic screening and brief intervention for reducing levels of alcohol consumption: a systematic review and meta-analysis. J Med Internet Res. 2014 Jun 2;16(6):e142.Full text  Abstract

31. Kypri K, Langley JD, Saunders JB, et al. Randomized controlled trial of web-based alcohol screening and brief intervention in primary care. Arch Intern Med. 2008 Mar 10;168(5):530-6. Abstract

32. Désy PM, Howard PK, Perhats C, et al. Alcohol screening, brief intervention, and referral to treatment conducted by emergency nurses: an impact evaluation. J Emerg Nurs. 2010 Nov;36(6):538-45. Abstract

33. Callon W, Beach MC, Saha S, et al. Assessing problematic substance use in HIV care: which questions elicit accurate patient disclosures? J Gen Intern Med. 2016 Oct;31(10):1141-7.Full text  Abstract

34. Babor TF, Higgins-Biddle JC, Saunders JB, et al. The Alcohol Use Disorders Identification Test (AUDIT). Guidelines for use in primary care, second edition. Geneva: World Health Organization; 2001.Full text

35. Agabio R, Nioi M, Serra C, et al. Alcohol use disorders in primary care patients in Cagliari, Italy. Alcohol Alcohol. 2006 May-Jun;41(3):341-4.Full text  Abstract

36. Berner MM, Kriston L, Bentele M, et al. The alcohol use disorders identification test for detecting at-risk drinking: a systematic review and meta-analysis. J Stud Alcohol Drugs. 2007 May;68(3):461-73. Abstract

37. First MB, Spitzer RL, Gibbon M, et al. Structured clinical interview for DSM-IV axis I disorders, clinician version (SCID-CV). Washington, DC: American Psychiatric Press; 1996.Full text

38. Sullivan JT, Swift RM, Lewis DC. Benzodiazepines requirements during alcohol withdrawal syndrome: clinical implications of using standardized withdrawal scale. J Clin Psychopharmacol. 1991 Oct;11(5):291-5. Abstract

39. Swift RM. Direct measurement of alcohol and its metabolites. Addiction. 2003 Dec;98(suppl 2):73-80. Abstract

40. Reus VI, Fochtmann LJ, Bukstein O, et al. The American Psychiatric Association practice guideline for the pharmacological treatment of patients with alcohol use disorder. Am J Psychiatry. 2018 Jan 1;175(1):86-90.Full text  Abstract

41. Bilban M, Vrhovec S, Karlovsek MZ. Blood biomarkers of alcohol abuse. Arh Hig Rada Toksikol. 2003 Dec;54(4):253-9. Abstract

42. Tilg H, Day CP. Management strategies in alcoholic liver disease. Nat Clin Pract Gastroenterol Hepatol. 2007 Jan;4(1):24-34. Abstract

43. Stein MD, Friedmann PD. Disturbed sleep and its relationship to alcohol use. Subst Abus. 2005 Mar;26(1):1-13. Abstract

44. Arackal BS, Benegal V. Prevalence of sexual dysfunction in male subjects with alcohol dependence. Indian J Psychiatry. 2007 Apr;49(2):109-12.Full text  Abstract

45. Grucza RA, Bierut LJ. Co-occurring risk factors for alcohol dependence and habitual smoking: update on findings from the Collaborative Study on the Genetics of Alcoholism. Alcohol Res Health. 2006;29(3):172-8. Abstract

46. US Preventive Services Task Force, Krist AH, Davidson KW, et al. Interventions for tobacco smoking cessation in adults, including pregnant persons: US Preventive Services Task Force recommendation statement. JAMA. 2021 Jan 19;325(3):265-79.Full text  Abstract

47. Reding KW, Cain KC, Jarrett ME, et al. Relationship between patterns of alcohol consumption and gastrointestinal symptoms among patients with irritable bowel syndrome. Am J Gastroenterol. 2013 Feb;108(2):270-6.Full text  Abstract

48. Chick J, Kemppainen E. Estimating alcohol consumption. Pancreatology. 2007;7(2-3):157-61. Abstract

49. Klatsky AL, Friedman GD, Armstrong MA. The relationships between alcoholic beverage use and other traits to blood pressure: a new Kaiser Permanente study. Circulation. 1986 Apr;73(4):628-36.Full text  Abstract

50. Addolorato G, Capristo E, Greco AV, et al. Influence of chronic alcohol abuse on body weight and energy metabolism: is excess ethanol consumption a risk factor for obesity or malnutrition? J Intern Med. 1998 Nov;244(5):387-95.Full text  Abstract

51. Addolorato G, Capristo E, Greco AV, et al. Three months of abstinence from alcohol normalizes energy expenditure and substrate oxidation in alcoholics: a longitudinal study. Am J Gastroenterol. 1998 Dec;93(12):2476-81. Abstract

52. Addolorato G, Leggio L, Ojetti V, et al. Effects of short-term moderate alcohol administration on oxidative stress and nutritional status in healthy males. Appetite. 2008 Jan;50(1):50-6. Abstract

53. Addolorato G, Capristo E, Leggio L, et al. Relationship between ghrelin levels, alcohol craving, and nutritional status in current alcoholic patients. Alcohol Clin Exp Res. 2006 Nov;30(11):1933-7. Abstract

54. Leggio L, Ferrulli A, Malandrino N, et al. Insulin but not insulin growth factor-1 correlates with craving in currently drinking alcohol-dependent patients. Alcohol Clin Exp Res. 2008 Mar;32(3):450-8. Abstract

55. Lingford-Hughes AR, Welch S, Peter L, et al. BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction, and comorbidity: recommendations from BAP. J Psychopharmacol. 2012 Jul;26(7):899-952. Abstract

56. American College of Surgeons. Best practices guidelines: screening and intervention for mental health disorders and substance use and misuse in the acute trauma patient. Dec 2022 [internet publication].Full text

57. US Preventive Services Task Force, Curry SJ, Krist AH, et al. Screening and behavioral counseling interventions to reduce unhealthy alcohol use in adolescents and adults: US Preventive Services Task Force recommendation statement. JAMA. 2018 Nov 13;320(18):1899-09.Full text  Abstract

58. Seale JP, Johnson JA, Clark DC, et al. A Multisite Initiative to Increase the Use of Alcohol Screening and Brief Intervention Through Resident Training and Clinic Systems Changes. Acad Med. 2015 Dec;90(12):1707-12.Full text  Abstract

59. Bush K, Kivlahan DR, McDonell MB, et al. The AUDIT alcohol consumption questions (AUDIT-C): an effective brief screening test for problem drinking. Ambulatory Care Quality Improvement Project (ACQUIP). Alcohol Use Disorders Identification Test. Arch Intern Med. 1998 Sep 14;158(16):1789-95.Full text  Abstract

60. National Institute for Health and Care Excellence. Alcohol-use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence. February 2011 [internet publication].Full text

61. Ray LA, Meredith LR, Kiluk BD, et al. Combined pharmacotherapy and cognitive behavioral therapy for adults with alcohol or substance use disorders: a systematic review and meta-analysis. JAMA Netw Open. 2020 Jun 1;3(6):e208279.Full text  Abstract

62. Kranzler HR, Soyka M. Diagnosis and pharmacotherapy of alcohol use disorder: a review. JAMA. 2018 Aug 28;320(8):815-24. Abstract

63. Sullivan JT, Sykora K, Schneiderman J, et al. Assessment of alcohol withdrawal: the revised Clinical Institute Withdrawal Assessment for Alcohol scale (CIWA-Ar). Br J Addiction. 1989;84:1353-1357. Abstract

64. Bertholet N, Daeppen JB, Wietlisbach V, et al. Reduction of alcohol consumption by brief alcohol intervention in primary care: systematic review and meta-analysis. Arch Intern Med. 2005 May 9;165(9):986-95.Full text  Abstract

65. Álvarez-Bueno C, Rodríguez-Martín B, García-Ortiz L, et al. Effectiveness of brief interventions in primary health care settings to decrease alcohol consumption by adult non-dependent drinkers: a systematic review of systematic reviews. Prev Med. 2015 Jul;76(suppl):S33-8. Abstract

66. Field C, Walters S, Marti CN, et al. A multisite randomized controlled trial of brief intervention to reduce drinking in the trauma care setting: how brief is brief? Ann Surg. 2014 May;259(5):873-80.Full text  Abstract

67. Kaner EF, Beyer FR, Muirhead C, et al. Effectiveness of brief alcohol interventions in primary care populations. Cochrane Database Syst Rev. 2018 Feb 24;(2):CD004148.Full text  Abstract

68. Miller WR, Rollnick S. Motivational interviewing: preparing people to change addictive behavior. New York, NY: Guilford Press; 1991.

69. Wendt DC, Gone JP. Group therapy for substance use disorders: a survey of clinician practices. J Groups Addict Recover. 2017;12(4):243-59. Abstract

70. Powers MB, Vedel E, Emmelkamp PM. Behavioral couples therapy (BCT) for alcohol and drug use disorders: a meta-analysis. Clin Psychol Rev. 2008 Jul;28(6):952-62. Abstract

71. Swift R. Emerging approaches to managing alcohol dependence. Am J Health Syst Pharm. 2007 Mar 1;64(5 suppl 3):S12-22. Abstract

72. Agosti V, Nunes EV, O'Shea D. Do manualized psychosocial interventions help reduce relapse among alcohol-dependent adults treated with naltrexone or placebo? A meta-analysis. Am J Addict. 2012 Nov-Dec;21(6):501-7. Abstract

73. Kelly JF, Hoeppner B, Stout RL, et al. Determining the relative importance of the mechanisms of behavior change within Alcoholics Anonymous: a multiple mediator analysis. Addiction. 2012 Feb;107(2):289-99.Full text  Abstract

74. Soyka M, Rösner S. Opioid antagonists for pharmacological treatment of alcohol dependence - a critical review. Curr Drug Abuse Rev. 2008 Nov;1(3):280-91. Abstract

75. Antonelli M, Ferrulli A, Sestito L, et al. Alcohol addiction - the safety of available approved treatment options. Expert Opin Drug Saf. 2018 Feb;17(2):169-77. Abstract

76. Ciraulo DA, Dong Q, Silverman BL, et al. Early treatment response in alcohol dependence with extended-release naltrexone. J Clin Psychiatry. 2008 Feb;69(2):190-5. Abstract

77. Lucey MR, Silverman BL, Illeperuma A, et al. Hepatic safety of once-monthly injectable extended-release naltrexone administered to actively drinking alcoholics. Alcohol Clin Exp Res. 2008 Mar;32(3):498-504. Abstract

78. Anton RF, O'Malley SS, Ciraulo DA, et al. Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial. JAMA. 2006 May 3;295(17):2003-17.Full text  Abstract

79. Jonas DE, Amick HR, Feltner C, et al. Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis. JAMA. 2014 May 14;311(18):1889-900.Full text  Abstract

80. Pettinati HM, Silverman BL, Battisti JJ, et al. Efficacy of extended-release naltrexone in patients with relatively higher severity of alcohol dependence. Alcohol Clin Exp Res. 2011 Oct;35(10):1804-11. Abstract

81. Anton RF, Latham P, Voronin K, et al. Efficacy of gabapentin for the treatment of alcohol use disorder in patients with alcohol withdrawal symptoms: a randomized clinical trial. JAMA Intern Med. 2020 May 1;180(5):728-36.Full text  Abstract

82. Anton RF, Myrick H, Wright TM, et al. Gabapentin combined with naltrexone for the treatment of alcohol dependence. Am J Psychiatry. 2011 Jul;168(7):709-17.Full text  Abstract

83. Johnson BA, Ait-Daoud N, Bowden CL, et al. Oral topiramate for treatment of alcohol dependence: a randomised controlled trial. Lancet. 2003 May 17;361(9370):1677-85. Abstract

84. Johnson BA, Rosenthal N, Capece JA, et al. Topiramate for treating alcohol dependence: a randomized controlled trial. JAMA. 2007 Oct 10;298(14):1641-51.Full text  Abstract

85. Johnson BA, Rosenthal N, Capece JA, et al. Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial. Arch Intern Med. 2008 Jun 9;168(11):1188-99. Abstract

86. Shinn AK, Greenfield SF. Topiramate in the treatment of substance-related disorders: a critical review of the literature. J Clin Psychiatry. 2010 May;71(5):634-48.Full text  Abstract

87. Kenna GA, Lomastro TL, Schiesl A, et al. Review of topiramate: an antiepileptic for the treatment of alcohol dependence. Curr Drug Abuse Rev. 2009 May;2(2):135-42. Abstract

88. Arbaizar B, Diersen-Sotos T, Gómez-Acebo I, et al. Topiramate in the treatment of alcohol dependence: a meta-analysis. Actas Esp Psiquiatr. 2010 Jan-Feb;38(1):8-12.Full text  Abstract

89. Swift RM. Topiramate for the treatment of alcohol dependence: initiating abstinence. Lancet. 2003 May 17;361(9370):1666-7. Abstract

90. Kranzler HR, Covault J, Feinn R, et al. Topiramate treatment for heavy drinkers: moderation by a GRIK1 polymorphism. Am J Psychiatry. 2014 Apr;171(4):445-52.Full text  Abstract

91. Rösner S, Hackl-Herrwerth A, Leucht S, et al. Acamprosate for alcohol dependence. Cochrane Database Syst Rev. 2010 Sep 8;(9):CD004332.Full text  Abstract

92. Mason BJ, Lehert P. Acamprosate for alcohol dependence: a sex-specific meta-analysis based on individual patient data. Alcohol Clin Exp Res. 2012 Mar;36(3):497-508.Full text  Abstract

93. Skinner MD, Lahmek P, Pham H, et al. Disulfiram efficacy in the treatment of alcohol dependence: a meta-analysis. PLoS One. 2014;9(2):e87366.Full text  Abstract

94. AshaRani PV, Karuvetil MZ, Brian TYW, et al. Prevalence and correlates of physical comorbidities in alcohol use disorder (AUD): a pilot study in treatment-seeking population. Int J Ment Health Addict. 2022 Jan 23;1-18.Full text  Abstract

95. Saitz R, Cheng DM, Winter M, et al. Chronic care management for dependence on alcohol and other drugs: the AHEAD randomized trial.JAMA. 2013 Sep 18;310(11):1156-67.Full text  Abstract

96. Ujhelyi Gomez K, Goodwin L, Jackson L, et al. Are psychosocial interventions effective in reducing alcohol consumption during pregnancy and motherhood? A systematic review and meta-analysis. Addiction. 2021 Jul;116(7):1638-63. Abstract

97. Smith EJ, Lui S, Terplan M. Pharmacologic interventions for pregnant women enrolled in alcohol treatment. Cochrane Database Syst Rev. 2009 Jul 8;(3):CD007361.Full text  Abstract

98. Towers CV, Katz E, Weitz B, et al. Use of naltrexone in treating opioid use disorder in pregnancy. Am J Obstet Gynecol. 2020 Jan;222(1):83.e1-83.e8. Abstract

99. DeVido J, Bogunovic O, Weiss RD. Alcohol use disorders in pregnancy. Harv Rev Psychiatry. 2015 Mar-Apr;23(2):112-21. Abstract

100. Tripodi SJ, Bender K, Litschge C, et al. Interventions for reducing adolescent alcohol abuse: a meta-analytic review. Arch Pediatr Adolesc Med. 2010 Jan;164(1):85-91.Full text  Abstract

101. Engle B, Macgowan MJ. A critical review of adolescent substance abuse group treatments. J Evid Based Soc Work. 2009 Jul;6(3):217-43. Abstract

102. Clark DB. Pharmacotherapy for adolescent alcohol use disorder. CNS Drugs. 2012 Jul 1;26(7):559-69. Abstract

103. O'Malley SS, Carroll KM. Psychotherapeutic considerations in pharmacological trials: alcoholism, clinical and experimental research. Alcohol Clin Exp Res. 1996 Oct;20(7 suppl):17A-22A. Abstract

104. Pettinati HM, Volpicelli JR, Pierce JD, et al. Improving naltrexone response: an intervention for medical practitioners to enhance medication compliance in alcohol dependent patients. J Addict Dis. 2000;19(1):71-83. Abstract

105. Modesto-Lowe V, Barron GC, Aronow B, et al. Gabapentin for alcohol use disorder: a good option, or cause for concern? Cleve Clin J Med. 2019 Dec;86(12):815-23.Full text  Abstract

106. Hobbs JD, Kushner MG, Lee SS, et al. Meta-analysis of supplemental treatment for depressive and anxiety disorders in patients being treated for alcohol dependence. Am J Addict. 2011 Jul-Aug;20(4):319-29.Full text  Abstract

107. Pettinati HM, Volpicelli JR, Kranzler HR, et al. Sertraline treatment for alcohol dependence: interactive effects of medication and alcoholic subtype. Alcohol Clin Exp Res. 2000 Jul;24(7):1041-9. Abstract

108. Kranzler HR, Burleson JA, Brown J, et al. Fluoxetine treatment seems to reduce the beneficial effects of cognitive-behavioral therapy in type B alcoholics. Alcohol Clin Exp Res. 1996 Dec;20(9):1534-41. Abstract

109. Cornelius JR, Bukstein OG, Wood DS, et al. Double-blind placebo-controlled trial of fluoxetine in adolescents with comorbid major depression and an alcohol use disorder. Addict Behav. 2009 Oct;34(10):905-9.Full text  Abstract

110. Heilig M, Egli M. Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacol Ther. 2006 Sep;111(3):855-76. Abstract

111. Johnson BA, Roache JD, Javors MA, et al. Ondansetron for reduction of drinking among biologically predisposed alcoholic patients: a randomized controlled trial. JAMA. 2000 Aug 23-30;284(8):963-71.Full text  Abstract

112. Addolorato G, Abenavoli L, Leggio L, et al. How many cravings? Pharmacological aspects of craving treatment in alcohol addiction: a review. Neuropsychobiology. 2005;51(2):59-66. Abstract

113. Johnson BA, Ait-Daoud N, Seneviratne C, et al. Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinking. Am J Psychiatry. 2011 Mar;168(3):265-75.Full text  Abstract

114. Tait RJ, Christensen H. Internet-based interventions for young people with problematic substance use: a systematic review. Med J Aust. 2010 Jun 7;192(11 suppl):S15-21. Abstract

115. Carey KB, Scott-Sheldon LA, Elliott JC, et al. Computer-delivered interventions to reduce college student drinking: a meta-analysis. Addiction. 2009 Nov;104(11):1807-19.Full text  Abstract

116. Gainsbury S, Blaszczynski A. A systematic review of internet-based therapy for the treatment of addictions. Clin Psychol Rev. 2011 Apr;31(3):490-8. Abstract

117. Carey KB, Scott-Sheldon LA, Elliott JC, et al. Face-to-face versus computer-delivered alcohol interventions for college drinkers: a meta-analytic review, 1998 to 2010. Clin Psychol Rev. 2012 Dec;32(8):690-703.Full text  Abstract

118. Bingham CR, Barretto AI, Walton MA, et al. Efficacy of a web-based, tailored, alcohol prevention/intervention program for college students: initial findings. J Am Coll Health. 2010 Jan-Feb;58(4):349-56. Abstract

119. Carey KB, Carey MP, Henson JM, et al. Brief alcohol interventions for mandated college students: comparison of face-to-face counseling and computer-delivered interventions. Addiction. 2011 Mar;106(3):528-37.Full text  Abstract

120. World Health Organization. Global strategy to reduce the harmful use of alcohol. May 2010 [internet publication].Full text

121. Grant BF. Prevalence and correlates of alcohol use and DSM-IV alcohol dependence in the United States: results of the National Longitudinal Alcohol Epidemiological Survey. J Stud Alcohol. 1997 Sep;58(5):464-73. Abstract

122. Finney JW, Hahn AC, Moos RH. The effectiveness of inpatient and outpatient treatment for alcohol abuse: the need to focus on mediators and moderators of setting effects. Addiction. 1996 Dec;91(12):1773-96. Abstract

123. Williams SH. Medications for treating alcohol dependence. Am Fam Physician. 2005 Nov 1;72(9):1775-80.Full text  Abstract

124. Mayo-Smith MF, Beecher LH, Fischer TL, et al. Management of alcohol withdrawal delirium: an evidence-based practice guideline. Arch Intern Med. 2004 Jul 12;164(13):1405-12.Full text  Abstract

125. Rathlev NK, Ulrich AS, Delanty N, et al. Alcohol-related seizures. J Emerg Med. 2006 Aug;31(2):157-63. Abstract

126. Shield KD, Parry C, Rehm J. Chronic diseases and conditions related to alcohol use. Alcohol Res. 2013;35(2):155-73. Abstract

127. Agabio R. Thiamine administration in alcohol-dependent patients. Alcohol Alcohol. 2005 Mar-Apr;40(2):155-6. Abstract

128. Thomson AD. Mechanisms of vitamin deficiency in chronic alcohol misusers and development of the Wernicke-Korsakoff syndrome. Alcohol Alcohol Suppl. 2000 May-Jun;35(1):2-7. Abstract

129. Dwivedi M, Misra SP. Mallory-Weiss syndrome: clinical features and management. J Assoc Physicians India. 1999 Apr;47(4):397-9. Abstract

130. Zhang X, Li SY, Brown RA, et al. Ethanol and acetaldehyde in alcoholic cardiomyopathy: from bad to ugly en route to oxidative stress. Alcohol. 2004 Apr;32(3):175-86. Abstract

131. Topiwala A, Allan CL, Valkanova V, et al. Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study. BMJ. 2017 Jun 6;357:j2353.Full text  Abstract

132. Kobayashi M, Pilishvili T, Farrar JL, et al. Pneumococcal vaccine for adults aged ≥19 years: recommendations of the Advisory Committee on Immunization Practices, United States, 2023. MMWR Recomm Rep 2023;72(No. RR-3):1–39.Full text

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