Evaluation of abnormal uterine bleeding

Last reviewed: 6 Apr 2025
Last updated: 14 Nov 2023

Summary

Differentials

Common

  • Polycystic ovary syndrome (PCOS)
  • Leiomyomata (uterine fibroids)
  • Endometrial polyp
  • Endometrial dysfunction
  • Iatrogenic
Full details

Uncommon

  • Endometrial malignancy
  • Adenomyosis
  • Coagulopathy
  • Hypothyroidism
  • Hyperprolactinemia
  • Cervical cancer
  • Ovarian cancer
Full details

Contributors

Authors

Bevan Brown, MBBS (Syd), FRANZCOG

Consultant Obstetrician and Gynaecologist

Sydney Adventist and Norwest Private Hospitals

Medical Co-Director

Sydney Fibroid Clinic

Sydney

Australia

Disclosures

BB declares that he is Medical Co-Director (with Dr Eisen Liang) of Sydney Fibroid Clinic. He has acted as a paid speaker for HOLOGIC in reference to their Myosure System and for Besins in relation to Slinda (drospirenone). He is a co-author with Dr Eisen Liang of several articles on fibroids, adenomyosis and their management, and co-author with Dr Liang of a book for patients on adenomyosis.

Peer reviewers

Mostafa Abuzeid, MD

Professor

Department of Obstetrics and Gynecology

Michigan State University

MI

Disclosures

MA declares that he has no competing interests.

Botros Rizk, MD, FACOG

Professor and Head of Reproductive Endocrinology and Infertility

Department of Obstetrics and Gynecology

University of South Alabama

AL

Disclosures

BR declares that he has no competing interests.

Peter Reid, BSc, MD, FRCOG, FRANZCOG

Specialist Gynaecologist

Peel Health Campus

Mandurah

Australia

Disclosures

PR declares that he has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

American College of Obstetricians and Gynecologists. ACOG committee opinion no. 557: management of acute abnormal uterine bleeding in nonpregnant reproductive-aged women. Apr 2013 [internet publication].Full text  Abstract

American College of Obstetricians and Gynecologists. Practice bulletin no. 128: diagnosis of abnormal uterine bleeding in reproductive-aged women. Jul 2012 [internet publication].

National Institute for Health and Care Excellence. Heavy menstrual bleeding: assessment and management. May 2021 [internet publication].Full text

American College of Radiology. ACR appropriateness criteria abnormal uterine bleeding. 2020 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

Use of this content is subject to our disclaimer