Rhabdomyolysis
შეჯამება
განსაზღვრება
ანამნეზი და გასინჯვა
ძირითადი დიაგნოსტიკური ფაქტორები
- recent crush injury
- prolonged immobilization
- presence of other risk factors
- muscular pain or weakness
სხვა დიაგნოსტიკური ფაქტორები
- general malaise
- dark urine
- muscular swelling
- muscular tenderness
- diminished peripheral pulse
- prolonged capillary refill
რისკფაქტორები
- trauma
- alcohol
- cocaine
- amphetamine
- phencyclidine
- narcotics
- diuretics
- statins
- salicylate toxicity
- toxins
- envenomation
- inflammatory disorders
- muscle hypoxia
- genetic disorders
- metabolic disorders
- infection
- increased body temperature
- antipsychotics
დიაგნოსტიკური კვლევები
1-ად შესაკვეთი გამოკვლევები
- serum creatine kinase (CK) level
- serum electrolytes
- renal function
- liver function
- CBC
- coagulation studies
- urine dipstick
- urine microscopy
- myoglobin levels
გასათვალისწინებელი კვლევები
- muscle biopsy
- thyroid-stimulating hormone
- erythrocyte sedimentation rate
- antinuclear antibodies
- toxicology screen
მკურნალობის ალგორითმი
crush injury and/or creatine kinase >5 times normal or >1000 IU/L
acute kidney injury refractory to initial therapy
კონტრიბუტორები
ავტორები
Chinmay Patel, MD, FASN
Nephrology Specialist
East Texas Kidney Specialists
Longview
TX
გაფრთხილება:
CP is an author of one reference cited in this topic.
Aditya Kadiyala, MD, MPH
Vice Chair
Department of Medicine
Division of Nephrology
University of Maryland
Charles Regional Medical Center
La Plata
MD
გაფრთხილება:
AK declares that he has no competing interests.
მადლიერება
Dr Chinmay Patel and Dr Aditya Kadiyala would like to gratefully acknowledge Dr Mark Shapiro, Dr Courtney Sommer, and Dr Robert D. Mathis, previous contributors to this topic.
გაფრთხილება:
MS is an author of references cited in this topic. CS and RDM declare that they have no competing interests.
რეცენზენტები
Timothy Albertson, MD, PhD, MPH
Chief
Division of Pulmonary and Critical Care Medicine
University of California, Davis
Sacramento
CA
Disclosures
TA declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Kodadek L, Carmichael Ii SP, Seshadri A, et al. Rhabdomyolysis: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document. Trauma Surg Acute Care Open. 2022;7(1):e000836.Full text Abstract
The Renal Association (UK). Clinical practice guideline: acute kidney injury (AKI). Aug 2019 [internet publication].Full text
Sawhney JS, Kasotakis G, Goldenberg A, et al. Management of rhabdomyolysis: a practice management guideline from the Eastern Association for the Surgery of Trauma. Am J Surg. 2022 Jul;224(1 pt a):196-204.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Myocardial infarction
- Influenza
- Fibromyalgia
More DifferentialsGuidelines
- Rhabdomyolysis: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
- Clinical practice guidelines for exertional rhabdomyolysis: a military medicine perspective
More Guidelines
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