Disease incidence increases with age, occurring in those older than 50 years and rarely in younger individuals. Incidence appears highest in those of northern European descent. PMR occurs in non-white populations, but the epidemiology has not been well studied in these populations. There appears to be a small increase in incidence in more recent studies, both in the US and in Europe. A geographical gradient has been observed in Europe, decreasing from north to south: the highest incidence rates have been reported in Norway and the lowest rates in Italy, Spain, and Israel. PMR rarely occurs in individuals younger than 50 years of age. For those 50 and older, the US prevalence has been estimated at 6/1,000, and the US average annual age- and sex-adjusted incidence estimated at 52.5/100,000. The incidence is higher in females at 61.7/100,000, compared with 39.9/100,000 in males. Cyclic fluctuations in the incidence of PMR have been observed, and there does not appear to be an increase in mortality associated with PMR.
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