Epidemiology

The 90th percentile for triglyceride levels has been historically noted to be approximately 2.8 mmol/L (250 mg/dL) in the US.[6] Because hypertriglyceridaemia is related to insulin resistance,[7] its prevalence is expected to continue to increase in industrialised countries. In the US and globally, the incidences of overweight/obese patients,[8] and associated metabolic syndrome,[9] and diabetes mellitus are increasing.[10] These are high-risk groups, especially those with central obesity. The incidence of chylomicronaemia is low. The Lipid Research Program prevalence study found 1.79 per 10,000 individuals had triglyceride levels >22.6 mmol/L (2000 mg/dL).[11] However, the incidence of this condition may also be increasing in association with the increasing prevalence of overweight or obese patients.[8] Data from the National Health and Nutrition Examination Survey show that from 2001 to 2006, 32% of the adult population in the US had triglyceride levels <1.7 mmol/L (>150 mg/dL).[12] Overall 14% had borderline high, 16% had high, and approximately 2% had very high triglyceride levels.

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