Pregnant women with suspected or confirmed Zika virus infection should have regular fetal ultrasounds to assess the fetus for the presence of microcephaly or other abnormalities. All pregnant women should be encouraged to attend scheduled antenatal visits.[13]Pan American Health Organization; World Health Organization. Provisional remarks on Zika virus infection in pregnant women: document for health care professionals. January 2016 [internet publication].
http://iris.paho.org/xmlui/handle/123456789/18600
Infants with congenital Zika syndrome should be followed up at 1, 3, 6, 9, 12, 18, and 24 months of age. Additional follow-up may be required if there are other complications. Follow-up beyond 24 months will depend on the child's individual needs.[179]World Health Organization. Screening, assessment and management of neonates and infants with complications associated with Zika virus exposure in utero. August 2016 [internet publication].
http://www.who.int/csr/resources/publications/zika/assessment-infants/en/
Assessment should include:[2]Adebanjo T, Godfred-Cato S, Viens L, et al. Update: interim guidance for the diagnosis, evaluation, and management of infants with possible congenital Zika virus infection - United States, October 2017. MMWR Morb Mortal Wkly Rep. 2017 Oct 20;66(41):1089-99.
https://www.cdc.gov/mmwr/volumes/66/wr/mm6641a1.htm?s_cid=mm6641a1_w
http://www.ncbi.nlm.nih.gov/pubmed/29049277?tool=bestpractice.com
[179]World Health Organization. Screening, assessment and management of neonates and infants with complications associated with Zika virus exposure in utero. August 2016 [internet publication].
http://www.who.int/csr/resources/publications/zika/assessment-infants/en/
Head circumference measurement
Neurodevelopmental assessment
Hearing screen
Ophthalmological assessment
Feeding and growth
Endocrine assessment
Psychological well-being of families and caregivers.
Infants with laboratory evidence of congenital infection who do not have any apparent abnormalities consistent with congenital infection should have ongoing developmental monitoring and screening, including hearing tests, by a primary care physician.[2]Adebanjo T, Godfred-Cato S, Viens L, et al. Update: interim guidance for the diagnosis, evaluation, and management of infants with possible congenital Zika virus infection - United States, October 2017. MMWR Morb Mortal Wkly Rep. 2017 Oct 20;66(41):1089-99.
https://www.cdc.gov/mmwr/volumes/66/wr/mm6641a1.htm?s_cid=mm6641a1_w
http://www.ncbi.nlm.nih.gov/pubmed/29049277?tool=bestpractice.com
CDC: Zika in babies in US territories - monitoring early health and development
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The World Health Organization (WHO) offers specific guidance for the screening, assessment, and management of neonates and infants with congenital Zika infection.
WHO: screening, assessment and management of neonates and infants with complications associated with Zika virus exposure in utero
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Patients with Guillain-Barre syndrome should be followed up for sequelae and multidisciplinary rehabilitation therapy.[151]World Health Organization. Identification and management of Guillain-Barré syndrome in the context of Zika virus - interim guidance. August 2016 [internet publication].
http://www.who.int/csr/resources/publications/zika/guillain-barre-syndrome/en/