acute respiratory failure
Median time to invasive mechanical ventilation was 7 days in a cohort of 47 patients.
acute respiratory distress syndrome
New or worsening respiratory symptoms within one week of presentation. Chest x-ray shows bilateral opacities.
High-flow oxygen (up to 50 mL/minute) is recommended in some patients, although mechanical ventilation and intubation is usually required.
acute renal failure
Possibly due to the presence of dipeptidyl peptidase-4 (DPP4) receptors in renal epithelial cells.
Detection of the virus in urine samples has been previously documented.
Occurs in a minority of patients late in the course of illness.
Underlying mechanism of action is unknown.
Patients may require vasopressor and inotrope support.
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