Hepatitis C appears to be endemic in most parts of the world, although the prevalence is not evenly distributed. The World Health Organization reports that approximately 1.75 million people were newly infected with hepatitis C in 2015 (an incidence rate of 23.7 in 100,000), bringing the total number of people living with the infection to 71 million (1% of the global population). European and Eastern Mediterranean regions have the highest prevalence rates (2.3% and 1.5%, respectively). There is considerable geographical and age variation in the incidence and prevalence of infection and of genotypes. The prevalence may be as high as 5% to 15% in some parts of the world, and different regions have a different risk profile and age demographic. Genotype 1 is the most prevalent worldwide, accounting for 46% of all cases, followed by genotype 3 (22%) and genotypes 2 and 4 (13% each).
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