Hyponatremia

References

Key articles

Spasovski G, Vanholder R, Allolio B, et al; Hyponatraemia Guideline Development Group. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur J Endocrinol. 2014 Feb 25;170(3):G1-47.Full text  Abstract

Adrogué HJ, Tucker BM, Madias NE. Diagnosis and management of hyponatremia: a review. JAMA. 2022 Jul 19;328(3):280-91. Abstract

Verbalis JG, Grossman A, Höybye C, et al. Review and analysis of differing regulatory indications and expert panel guidelines for the treatment of hyponatremia. Curr Med Res Opin. 2014 Jul;30(7):1201-7. Abstract

Hoorn EJ, Zietse R. Diagnosis and treatment of hyponatremia: compilation of the guidelines. J Am Soc Nephrol. 2017 May;28(5):1340-9.Full text  Abstract

Reference articles

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3. Adrogué HJ, Tucker BM, Madias NE. Diagnosis and management of hyponatremia: a review. JAMA. 2022 Jul 19;328(3):280-91. Abstract

4. Adrogué HJ, Madias NE. The syndrome of inappropriate antidiuresis. N Engl J Med. 2023 Oct 19;389(16):1499-509.

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6. Giordano M, Ciarambino T, Castellino P, et al. Diseases associated with electrolyte imbalance in the ED: age-related differences. Am J Emerg Med. 2016 Oct;34(10):1923-1926.Full text  Abstract

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8. Zilberberg MD, Exuzides A, Spalding J, et al. Epidemiology, clinical and economic outcomes of admission hyponatremia among hospitalized patients. Curr Med Res Opin. 2008 Jun;24(6):1601-8. Abstract

9. Verbalis JG, Grossman A, Höybye C, et al. Review and analysis of differing regulatory indications and expert panel guidelines for the treatment of hyponatremia. Curr Med Res Opin. 2014 Jul;30(7):1201-7. Abstract

10. Funk GC, Lindner G, Druml W, et al. Incidence and prognosis of dysnatremias present on ICU admission. Intensive Care Med. 2010 Feb;36(2):304-11. Abstract

11. Braun MM, Barstow CH, Pyzocha NJ. Diagnosis and management of sodium disorders: hyponatremia and hypernatremia. Am Fam Physician. 2015 Mar 1;91(5):299-307.Full text  Abstract

12. Freda BJ, Davidson MB, Hall PM. Evaluation of hyponatremia: a little physiology goes a long way. Cleve Clin J Med. 2004 Aug;71(8):639-50. Abstract

13. Moen V, Brudin L, Rundgren M, et al. Hyponatremia complicating labour - rare or unrecognised? A prospective observational study. BJOG. 2009 Mar;116(4):552-61.Full text  Abstract

14. Morton A, Lumchee M, Kumar S, et al. Pregnancy outcomes in women with hyponatraemia and preeclampsia: case series and literature review. Pregnancy Hypertens. 2021 Dec;26:38-41. Abstract

15. Friedman E, Shadel M, Halkin H, et al. Thiazide-induced hyponatremia: reproducibility by single dose rechallenge and an analysis of pathogenesis. Ann Intern Med. 1989 Jan 1;110(1):24-30. Abstract

16. Bennett BL, Hew-Butler T, Rosner MH, et al. Wilderness Medical Society clinical practice guidelines for the management of exercise-associated hyponatremia: 2019 update. Wilderness Environ Med. 2020 Mar;31(1):50-62.Full text  Abstract

17. Grant P, Ayuk J, Bouloux PM, et al. The diagnosis and management of inpatient hyponatraemia and SIADH. Eur J Clin Invest. 2015 Aug;45(8):888-94.Full text  Abstract

18. Jacob S, Spinler SA. Hyponatremia associated with selective serotonin-reuptake inhibitors in older adults. Ann Pharmacother. 2006 Sep;40(9):1618-22. Abstract

19. Fabian TJ, Amico JA, Kroboth PD, et al. Paroxetine-induced hyponatremia in older adults: a 12-week prospective study. Arch Intern Med. 2004 Feb 9;164(3):327-32. Abstract

20. Wakil A, Ng JM, Atkin SL. Investigating hyponatraemia. BMJ. 2011 Mar 7;342:d1118. Abstract

21. Mathus-Vliegen EMH, van der Vliet K, Wignand-van der Storm IJ, et al. Split-dose bowel cleansing with picosulphate is safe and better tolerated than 2-l polyethylene glycol solution. Eur J Gastroenterol Hepatol. 2018 Jul;30(7):709-717.Full text  Abstract

22. Reumkens A, van der Zander Q, Winkens B, et al. Electrolyte disturbances after bowel preparation for colonoscopy: systematic review and meta-analysis. Dig Endosc. 2022 Jul;34(5):913-26.Full text  Abstract

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24. Adrogué HJ, Madias NE. Hyponatremia. N Engl J Med. 2000 May 25;342(21):1581-9. Abstract

25. Shima S, Niimi Y, Moteki Y, et al. Prognostic significance of hyponatremia in acute stroke: a systematic review and meta-analysis. Cerebrovasc Dis. 2020;49(5):531-9.Full text  Abstract

26. Królicka AL, Kruczkowska A, Krajewska M, et al. Hyponatremia in infectious diseases-a literature review. Int J Environ Res Public Health. 2020 Jul 23;17(15):5320.Full text  Abstract

27. Kilpatrick ES. Disorders of sodium balance: hypothyroidism and hyponatraemia: an old wives' tale? BMJ. 2006 Apr 8;332(7545):854.Full text  Abstract

28. Hanna FW, Scanlon MF. Hyponatraemia, hypothyroidism, and role of arginine-vasopressin. Lancet. 1997 Sep 13;350(9080):755-6. Abstract

29. Schrier RW. Vasopressin and aquaporin 2 in clinical disorders of water homeostasis. Semin Nephrol. 2008 May;28(3):289-96.Full text  Abstract

30. Warner MH, Holding S, Kilpatrick ES. The effect of newly diagnosed hypothyroidism on serum sodium concentrations: a retrospective study. Clin Endocrinol (Oxf). 2006 May;64(5):598-9. Abstract

31. Grohé C, Berardi R, Burst V. Hyponatraemia-SIADH in lung cancer diagnostic and treatment algorithms. Crit Rev Oncol Hematol. 2015 Oct;96(1):1-8. Abstract

32. Fiordoliva I, Meletani T, Baleani MG, et al. Managing hyponatremia in lung cancer: latest evidence and clinical implications. Ther Adv Med Oncol. 2017 Nov;9(11):711-9.Full text  Abstract

33. Workeneh BT, Jhaveri KD, Rondon-Berrios H. Hyponatremia in the cancer patient. Kidney Int. 2020 Oct;98(4):870-82. Abstract

34. Marquina G, Gomez-Hoyos E, Runkle I. The management of hyponatremia in cancer patients: a practical view in Spain. J Cancer Metastasis Treat. 2020 Mar 10;6:6.Full text

35. Murthy K, Ondrey GJ, Malkani N, et al. The effects of hyponatremia on bone density and fractures: a systemic review and meta-analysis. Endocr Pract. 2019 Apr;25(4):366-78.Full text  Abstract

36. Corona G, Norello D, Parenti G, et al. Hyponatremia, falls and bone fractures: a systematic review and meta-analysis. Clin Endocrinol (Oxf). 2018 Oct;89(4):505-13. Abstract

37. Demertzidou E, Zill-E-Huma R, Modi M. Peripartum hyponatraemia: an overview of physiology, prevention and management. Obstet Gynaecol​. 2022 May 17; 24(3): 188-94.

38. Wang J, Xu E, Xiao Y. Isotonic versus hypotonic maintenance IV fluids in hospitalized children: a meta-analysis. Pediatrics. 2014 Jan;133(1):105-13. Abstract

39. Feld LG, Neuspiel DR, Foster BA, et al. Clinical Practice Guideline: Maintenance Intravenous Fluids in Children. Pediatrics. 2018 Dec;142(6):.Full text  Abstract

40. Hew-Butler T, Rosner MH, Fowkes-Godek S, et al. Statement of the 3rd International exercise-associated hyponatremia consensus development conference, Carlsbad, California, 2015. Br J Sports Med. 2015 Nov;49(22):1432-46.Full text  Abstract

41. Jacob P, Dow C, Lasker SS, et al. Hyponatraemia in primary care. BMJ. 2019 May 9;365:l1774.Full text  Abstract

42. Hillier TA, Abbott RD, Barrett EJ. Hyponatremia: evaluating the correction factor for hyperglycemia. Am J Med. 1999 Apr;106(4):399-403. Abstract

43. Nguyen MK, Kurtz I. Derivation of a new formula for calculating urinary electrolyte-free water clearance based on the Edelman equation. Am J Physiol Renal Physiol. 2005 Jan;288(1):F1-7.Full text  Abstract

44. Lindner G, Schwarz C. Electrolyte-free water clearance versus modified electrolyte-free water clearance: do the results justify the effort? Nephron Physiol. 2012;120(1):p1-5. Abstract

45. Liamis G, Liberopoulos E, Barkas F, et al. Diabetes mellitus and electrolyte disorders. World J Clin Cases. 2014 Oct 16;2(10):488-96.Full text  Abstract

46. Tandukar S, Sterns RH, Rondon-Berrios H. Osmotic demyelination syndrome following correction of hyponatremia by ≤10 mEq/L per day. Kidney360. 2021 Sep 30;2(9):1415-23.Full text  Abstract

47. MacMillan TE, Cavalcanti RB. Outcomes in severe hyponatremia treated with and without desmopressin. Am J Med. 2018 Mar;131(3):317.e1-317.e10. Abstract

48. Baek SH, Jo YH, Ahn S, et al. Risk of overcorrection in rapid Intermittent bolus vs slow continuous infusion therapies of hypertonic saline for patients with symptomatic hyponatremia: the SALSA randomized clinical trial. JAMA Intern Med. 2021 Jan 1;181(1):81-92.Full text  Abstract

49. Sterns RH. Disorders of plasma sodium - causes, consequences, and correction. N Engl J Med. 2015 Jan 1;372(1):55-65. Abstract

50. Nagler EV, Vanmassenhove J, van der Veer SN, et al. Diagnosis and treatment of hyponatremia: a systematic review of clinical practice guidelines and consensus statements. BMC Med. 2014 Dec 11;12:1.Full text  Abstract

51. Buchkremer F, Segerer S, Bock A. Monitoring urine flow to prevent overcorrection of hyponatremia: derivation of a safe upper limit based on the Edelman equation. Am J Kidney Dis. 2019 Jan;73(1):143-5. Abstract

52. Dixon MB, Lien YH. Tolvaptan and its potential in the treatment of hyponatremia. Ther Clin Risk Manag. 2008 Dec;4(6):1149-55.Full text  Abstract

53. Nagler EV, Haller MC, Van Biesen W, et al. Interventions for chronic non-hypovolaemic hypotonic hyponatraemia. Cochrane Database Syst Rev. 2018 Jun 28;(6):CD010965.Full text  Abstract

54. Zhou Y, Yang W, Liu G, et al. Risks of vaptans in hypernatremia and serum sodium overcorrection: a systematic review and meta-analysis of randomised controlled trials. Int J Clin Pract. 2021 Jun;75(6):e13939. Abstract

55. Rondon-Berrios H, Tandukar S, Mor MK, et al. Urea for the treatment of hyponatremia. Clin J Am Soc Nephrol. 2018 Nov 7;13(11):1627-32. Abstract

56. Sterns RH, Silver SM, Hix JK. Urea for hyponatremia? Kidney Int. 2015 Feb;87(2):268-70.Full text  Abstract

57. Hoorn EJ, Zietse R. Diagnosis and treatment of hyponatremia: compilation of the guidelines. J Am Soc Nephrol. 2017 May;28(5):1340-9.Full text  Abstract

58. Chen Z, Jia Q, Liu C. Association of hyponatremia and risk of short- and long-term mortality in patients with stroke: a systematic review and meta-analysis. J Stroke Cerebrovasc Dis. 2019 Jun;28(6):1674-83. Abstract

59. Sun L, Hou Y, Xiao Q, et al. Association of serum sodium and risk of all-cause mortality in patients with chronic kidney disease: a meta-analysis and sysematic review. Sci Rep. 2017 Nov 21;7(1):15949.Full text  Abstract

60. Renneboog B, Musch W, Vandemergel X, et al. Mild chronic hyponatremia is associated with falls, unsteadiness, and attention deficits. Am J Med. 2006 Jan;119(1):71.e1-8. Abstract

61. Verbalis JG, Barsony J, Sugimura Y, et al. Hyponatremia-induced osteoporosis. J Bone Miner Res. 2010 Mar;25(3):554-63.Full text  Abstract

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