Chikungunya virus was first isolated in Tanzania in 1952.[6] Occasional outbreaks have since occurred in Africa, Asia, and the Indian subcontinent, with the largest outbreak occurring on Réunion Island in the Indian Ocean, where around 35% of the island’s 750,000 inhabitants were infected in 2005 and 2006.[7] Since then, the disease has spread to all continents, reaching the Americas via the Caribbean islands in 2013.[8] Increased mobility of people across countries, adaptation of the virus to a more widespread vector (Aedes albopictus), and climate changes have favoured global dissemination of the disease.

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