Summary
Differentials
Common
- Purpura simplex
- Senile purpura
- Medications
- Alcohol abuse
- Drug-induced thrombocytopenia
- Platelet storage pool disease
- von Willebrand disease
- Vitamin K deficiency
- Cirrhosis
- Vasculitis
Uncommon
- Hereditary haemorrhagic telangiectasia (HHT)
- Cushing's syndrome
- Child abuse
- Elder abuse
- Immune thrombocytopenia (ITP)
- Thrombotic thrombocytopenic purpura (TTP)
- Haemolytic uraemic syndrome (HUS)
- Disseminated intravascular coagulation (DIC)
- Wiskott-Aldrich syndrome
- MYH9-related disorders
- Bernard-Soulier disease
- Thrombocytopenia with absent radius (TAR) syndrome
- Glanzmann's thrombasthenia
- Acute myelogenous leukaemia
- Acute lymphocytic leukaemia
- Hodgkin's lymphoma
- Non-Hodgkin's lymphoma
- Multiple myeloma
- Solid tumour with infiltration of bone marrow
- Myelofibrosis
- Myelodysplastic syndrome
- Aplastic anaemia
- Haemophilia
- Factor V, VII, X, or XI deficiency
- Acquired coagulation inhibitors
- Vitamin C deficiency
- Marfan's syndrome
- Ehlers-Danlos syndrome
- Acute liver failure
- Gardner-Diamond syndrome
Contributors
Authors VIEW ALL
Assistant Professor of Internal Medicine
The Ohio State University
Columbus
OH
Disclosures
TW declares that she has received an honorarium from Daiichi Sankyo.
Professor of Internal Medicine
The Ohio State University
Columbus
OH
Disclosures
EHK declares that he has no competing interests.
Peer reviewers VIEW ALL
Associate Professor
Department of Medicine
McMaster University
Hamilton
Ontario
Canada
Disclosures
DMA has received speaking honoraria from Amgen for presentation on immune thrombocytopenia; consulting fees from Amgen, and Bristol-Myers Squibb for ITP related studies; and research grants from Amgen, GlaxoSmithKline, and Hoffman-La Roche for clinical studies in ITP. He is co-author of a reference cited in this topic.
Clinical Scholar
McMaster University
St. Joseph’s Healthcare Hamilton
Hamilton
Ontario
Canada
Disclosures
DS declares that she has no competing interests.
Assistant Professor of Pediatrics
Nationwide Children’s Hospital
Ohio State University
Columbus
OH
Disclosures
RK declares that he has no competing interests.
Consultant Haematologist
Oxford Haemophilia & Thrombosis Centre
Churchill Hospital
Oxford
UK
Disclosures
DK declares that he has no competing interests.
Professor of Haematology
University of Liverpool
Liverpool
UK
Disclosures
CHT declares that he has no competing interests.
Consultant Haematologist
Heart of England NHS Foundation Trust
Birmingham
UK
Disclosures
SP has received a speaker fee from Janssen.
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