Evaluation of easy bruising

Última revisão: 18 Aug 2025
Última atualização: 22 Aug 2024

Resumo

Diagnósticos diferenciais

comuns

  • Purpura simplex
  • Actinic purpura (also known as senile purpura)
  • Medications
  • Alcohol use disorder
  • Drug-induced thrombocytopenia
  • Platelet storage pool disease
  • von Willebrand disease (vWD)
  • Vitamin K deficiency
  • Cirrhosis
  • Vasculitis
Detalhes completos

Incomuns

  • Hereditary hemorrhagic telangiectasia (HHT)
  • Cushing syndrome
  • Child abuse
  • Elder abuse
  • Immune thrombocytopenia (ITP)
  • Thrombotic thrombocytopenic purpura (TTP)
  • Hemolytic uremic syndrome (HUS)
  • Disseminated intravascular coagulation
  • Wiskott-Aldrich syndrome
  • MYH9-related disorders
  • Bernard-Soulier disease
  • Thrombocytopenia with absent radius syndrome
  • Glanzmann thrombasthenia
  • Acute myelogenous leukemia
  • Acute lymphocytic leukemia
  • Hodgkin lymphoma
  • Non-Hodgkin lymphoma
  • Multiple myeloma
  • Solid tumor with infiltration of bone marrow
  • Myelofibrosis
  • Myelodysplastic syndrome
  • Aplastic anemia
  • Hemophilia
  • Factor V, VII, X, or XI deficiency
  • Acquired coagulation inhibitors
  • Vitamin C deficiency
  • Marfan syndrome
  • Ehlers-Danlos syndrome
  • Acute liver failure
  • Gardner-Diamond syndrome
Detalhes completos

Colaboradores

Autores

Tzu-Fei Wang, MD
Tzu-Fei Wang

Assistant Professor of Internal Medicine

The Ohio State University

Columbus

OH

Declarações

TW declares that she has received an honorarium from Daiichi Sankyo.

Eric H. Kraut, MD
Eric H. Kraut

Professor of Internal Medicine

The Ohio State University

Columbus

OH

Declarações

EHK declares that he has no competing interests.

Revisores

Donald M. Arnold, MDCM, MSc

Associate Professor

Department of Medicine

McMaster University

Hamilton

Ontario

Canada

Declarações

DMA has received speaking honoraria from Amgen for presentation on immune thrombocytopenia; consulting fees from Amgen, and Bristol-Myers Squibb for ITP related studies; and research grants from Amgen, GlaxoSmithKline, and Hoffman-La Roche for clinical studies in ITP. He is co-author of a reference cited in this topic.

Deborah Siegel, MD, MSc, FRCPC

Clinical Scholar

McMaster University

St. Joseph’s Healthcare Hamilton

Hamilton

Ontario

Canada

Declarações

DS declares that she has no competing interests.

Riten Kumar, MD, MSc

Assistant Professor of Pediatrics

Nationwide Children’s Hospital

Ohio State University

Columbus

OH

Declarações

RK declares that he has no competing interests.

David Keeling, BSc, MD, FRCP, FRCPath

Consultant Haematologist

Oxford Haemophilia & Thrombosis Centre

Churchill Hospital

Oxford

UK

Declarações

DK declares that he has no competing interests.

Professor Cheng-Hock Toh, MBChB, MD, FRCP, FRCPath

Professor of Haematology

University of Liverpool

Liverpool

UK

Declarações

CHT declares that he has no competing interests.

Shankaranarayana Paneesha, MBBS, MD, FRCP, FRCPath

Consultant Haematologist

Heart of England NHS Foundation Trust

Birmingham

UK

Declarações

SP has received a speaker fee from Janssen.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Referências

Nossas equipes internas de editoria e de evidências trabalham em conjunto com colaboradores internacionais especializados e pares revisores para garantir que forneçamos acesso às informações o mais clinicamente relevantes possível.

Principais artigos

Faughnan ME, Mager JJ, Hetts SW, et al. Second international guidelines for the diagnosis and management of hereditary hemorrhagic telangiectasia. Ann Intern Med. 2020 Dec 15;173(12):989-1001.Texto completo  Resumo

Tiede A, Collins P, Knoebl P, et al. International recommendations on the diagnosis and treatment of acquired hemophilia A. Haematologica. 2020 Jul;105(7):1791-801.Texto completo  Resumo

Neunert C, Terrell DR, Arnold DM, et al. American Society of Hematology 2019 guidelines for immune thrombocytopenia. Blood Adv. 2019 Dec 10;3(23):3829-66.Texto completo  Resumo

Rodeghiero F, Tosetto A, Abshire T, et al. ISTH/SSC bleeding assessment tool: a standardized questionnaire and a proposal for a new bleeding score for inherited bleeding disorders. J Thromb Haemost. 2010;8:2063-2065.Texto completo  Resumo

Platton S, Baker P, Bowyer A, et al. Guideline for laboratory diagnosis and monitoring of von Willebrand disease: a joint guideline from the United Kingdom Haemophilia Centre Doctors' Organisation and the British Society for Haematology. Br J Haematol. 2024 May;204(5):1714-31.Texto completo

Artigos de referência

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