Carotid artery stenosis

Carotid artery stenosis is a narrowing of the lumen of the carotid artery. Approximately 10% to 15% of all ischaemic strokes are associated with carotid artery stenosis.

Atherosclerotic plaque in the cervical carotid artery is the most common cause. Plaque disruption and atheroembolisation into the intracranial circulation is the most common mechanism for stroke.

The majority of carotid artery stenoses are mild or moderate, and asymptomatic.

Duplex ultrasonography is a commonly used mode of diagnosis; computed tomography angiography or magnetic resonance angiography are alternatives that also help to define the anatomy if intervention is indicated.

Most patients with carotid artery stenosis should receive antiplatelet therapy, and all should receive risk factor modification.

Carotid revascularisation of moderate- or high-grade recently symptomatic carotid artery stenosis prevents future stroke.

The benefit of revascularisation for asymptomatic stenosis is less certain.

Carotid artery stenosis is a narrowing of the lumen of the carotid artery. Atherosclerotic plaque in the cervical carotid artery is the most common cause. The unique haemodynamics at the carotid bifurcation predisposes this area to atherosclerosis. The majority of patients have mild- or moderate-sized plaques, while some develop high-grade stenosis. A small percentage of plaques may rupture and embolise to occlude intracranial arteries, causing a transient ischaemic attack or stroke, or occlude retinal arteries to cause transient monocular blindness (amaurosis fugax) or retinal strokes.