Meconium aspiration syndrome

Thornton PD, Campbell RT, Mogos MF, et al. Meconium aspiration syndrome: incidence and outcomes using discharge data. Early Hum Dev. 2019 Sep;136:21-6. Abstract

Singh BS, Clark RH, Powers RJ, et al. Meconium aspiration syndrome remains a significant problem in the NICU: outcomes and treatment patterns in term neonates admitted for intensive care during a ten-year period. J Perinatol. 2009 Jul;29(7):497-503. Abstract

Vidyasagar D, Harris V, Pildes RS. Assisted ventilation in infants with meconium aspiration syndrome. Pediatrics. 1975 Aug;56(2):208-13. Abstract

Wiswell TE, Gannon CM, Jacob J, et al. Delivery room management of the apparently vigorous meconium-stained neonate: results of the multicenter, international collaborative trial. Pediatrics. 2000 Jan;105(1 Pt 1):1-7. Abstract

Yamada NK, Szyld E, Strand ML, et al. 2023 American Heart Association and American Academy of Pediatrics focused update on neonatal resuscitation: an update to the American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2024 Jan 2;149(1):e157-66.Full text  Abstract

1. Rossi EM, Philipson EH, Williams TG, et al. Meconium aspiration syndrome: intrapartum and neonatal attributes. Am J Obstet Gynecol. 1989 Nov;161(5):1106-10. Abstract

2. Fanaroff AA. Meconium aspiration syndrome: historical aspects. J Perinatol. 2008 Dec;28(suppl 3):S3-7.Full text  Abstract

3. Cleary GM, Wiswell TE. Meconium-stained amniotic fluid and meconium aspiration syndrome: an update. Pediatr Clin North Am. 1998 Jun;45(3):511-29. Abstract

4. Balchin I, Whittaker JC, Lamont RF, et al. Maternal and fetal characteristics associated with meconium-stained amniotic fluid. Obstet Gynecol. 2011 Apr;117(4):828-35. Abstract

5. Wiswell TE, Pinchi S. Aspiration syndromes in neonatal respiratory disorders. In: Greenough A, Milner AD, eds. Neonatal respiratory disorders. London, UK: Arnold; 2003:350.

6. Swarnam K, Soraisham AS, Sivanandan S. Advances in the management of meconium aspiration syndrome. Int J Pediatr. 2012 Nov 22;2012:359571.Full text  Abstract

7. Thornton PD, Campbell RT, Mogos MF, et al. Meconium aspiration syndrome: incidence and outcomes using discharge data. Early Hum Dev. 2019 Sep;136:21-6. Abstract

8. Yoder BA, Kirsch EA, Barth WH, et al. Changing obstetric practices associated with decreasing incidence of meconium aspiration syndrome. Obstet Gynecol. 2002 May;99(5 Pt 1):731-9. Abstract

9. Singh BS, Clark RH, Powers RJ, et al. Meconium aspiration syndrome remains a significant problem in the NICU: outcomes and treatment patterns in term neonates admitted for intensive care during a ten-year period. J Perinatol. 2009 Jul;29(7):497-503. Abstract

10. Fischer C, Rybakowski C, Ferdynus C, et al. A population-based study of meconium aspiration syndrome in neonates born between 37 and 43 weeks of gestation. Int J Pediatr. 2012;2012:321545.Full text  Abstract

11. Vivian-Taylor J, Sheng J, Hadfield RM, et al. Trends in obstetric practices and meconium aspiration syndrome: a population-based study. BJOG. 2011 Dec;118(13):1601-7.Full text  Abstract

12. Ward C, Caughey AB. The risk of meconium aspiration syndrome (MAS) increases with gestational age at term. J Matern Fetal Neonatal Med. 2022 Jan;35(1):155-60. Abstract

13. Short BL. Extracorporeal membrane oxygenation: use in meconium aspiration syndrome. J Perinatol. 2008 Dec;28(suppl 3):S79-83.Full text  Abstract

14. Grobman WA, Caughey AB. Elective induction of labor at 39 weeks compared with expectant management: a meta-analysis of cohort studies. Am J Obstet Gynecol. 2019 Oct;221(4):304-10. Abstract

15. Middleton P, Shepherd E, Morris J, et al. Induction of labour at or beyond 37 weeks' gestation. Cochrane Database Syst Rev. 2020 Jul 15;(7):CD004945.Full text  Abstract

16. Velaphi S, Van Kwawegen A. Meconium aspiration syndrome requiring assisted ventilation: perspective in a setting with limited resources. J Perinatol. 2008 Dec;28(suppl 3):S36-42.Full text  Abstract

17. Anwar Z, Butt TK, Kazi MY. Mortality in meconium aspiration syndrome in hospitalized babies. J Coll Physicians Surg Pak. 2011 Nov;21(11):695-9. Abstract

18. Abramovich DR, Gray ES. Physiologic fetal defecation in midpregnancy. Obstet Gynecol. 1982 Sep;60(3):294-6. Abstract

19. Usta IM, Merser BM, Sibai BM. Risk factors for meconium aspiration syndrome. Obstet Gynecol. 1995 Aug;86(2):230-4. Abstract

20. Tran SH, Caughey AB, Musci TJ. Meconium-stained amniotic fluid is associated with puerperal infections. Am J Obstet Gynecol. 2003 Sep;189(3):746-50. Abstract

21. Vidyasagar D, Harris V, Pildes RS. Assisted ventilation in infants with meconium aspiration syndrome. Pediatrics. 1975 Aug;56(2):208-13. Abstract

22. Lee J, Romero R, Lee KA, et al. Meconium aspiration syndrome: a role for fetal systemic inflammation. Am J Obstet Gynecol. 2016 Mar;214(3):366;e1-9. Abstract

23. Vidyasagar D, Zagariya A. Studies of meconium-induced lung injury: inflammatory cytokine expression and apoptosis. J Perinatol. 2008 Dec;28(suppl 3):S102-7.Full text  Abstract

24. Sun B, Curstedt T, Robertson B. Surfactant inhibition in experimental meconium aspiration. Acta Paediatr. 1993 Feb;82(2):182-9. Abstract

25. Abman SH. Pathogenesis and treatment of neonatal and postnatal pulmonary hypertension. Curr Opin Pediatr. 1994 Jun;6(3):239-47. Abstract

26. Li JY, Wang PH, Vitale SG, et al. Pregnancy-induced hypertension is an independent risk factor for meconium aspiration syndrome: a retrospective population based cohort study. Taiwan J Obstet Gynecol. 2019 May;58(3):396-400.Full text  Abstract

27. Oliveira CPL, Flôr-de-Lima F, Rocha GMD, et al. Meconium aspiration syndrome: risk factors and predictors of severity. J Matern Fetal Neonatal Med. 2019 May;32(9):1492-8. Abstract

28. Rabie N, Magann E, Steelman S, et al. Oligohydramnios in complicated and uncomplicated pregnancy: a systematic review and meta-analysis. Ultrasound Obstet Gynecol. 2017 Apr;49(4):442-9.Full text  Abstract

29. Wiswell TE, Gannon CM, Jacob J, et al. Delivery room management of the apparently vigorous meconium-stained neonate: results of the multicenter, international collaborative trial. Pediatrics. 2000 Jan;105(1 Pt 1):1-7. Abstract

30. Dargaville PA, Copnell B; Australian and New Zealand Neonatal Network. The epidemiology of meconium aspiration syndrome: incidence, risk factors, therapies, and outcome. Pediatrics. 2006 May;117(5):1712-21. Abstract

31. American Academy of Pediatrics Committee on Fetus and Newborn. Levels of neonatal care. Pediatrics. 2012 Sep;130(3):587-97. Reaffirmed 2015.Full text  Abstract

32. Siriwachirachai T, Sangkomkamhang US, Lumbiganon P, et al. Antibiotics for meconium-stained amniotic fluid in labour for preventing maternal and neonatal infections. Cochrane Database Syst Rev. 2014 Nov 6;(11):CD007772.Full text  Abstract

33. Fraser WD, Hofmeyr J, Lede R, et al; Amnioinfusion Trial Group. Amnioinfusion for the prevention of the meconium aspiration syndrome. N Engl J Med. 2005 Sep 1;353(9):909-17.Full text  Abstract

34. Velaphi S, Vidyasagar D. The pros and cons of suctioning at the perineum (intrapartum) and post-delivery with and without meconium. Semin Fetal Neonatal Med. 2008 Dec;13(6):375-82. Abstract

35. Vain NE, Szyld EG, Prudent LM, et al. Oropharyngeal and nasopharyngeal suctioning of meconium-stained neonates before delivery of their shoulders: multicentre, randomised controlled trial. Lancet. 2004 Aug 14-20;364(9434):597-602. Abstract

36. Falciglia HS, Henderschott C, Potter P, et al. Does DeLee suction at the perineum prevent meconium aspiration syndrome? Am J Obstet Gynecol. 1992 Nov;167(5):1243-9. Abstract

37. Chettri S, Adhisivam B, Bhat BV. Endotracheal suction for nonvigorous neonates born through meconium stained amniotic fluid: a randomized controlled trial. J Pediatr. 2015;166:1208-1213. Abstract

38. Nangia S, Sunder S,Biswas R, et al. Endotracheal suction in term nonvigorous meconium stained neonates - a pilot study. Resuscitation. 2016;105:79-84. Abstract

39. Kiremitci S, Tuzun F, Yesilirmak DC, et al. Is gastric aspiration needed for newborn management in delivery room? Resuscitation. 2011 Jan;82(1):40-4. Abstract

40. Yadav SK, Venkatnarayan K, Adhikari KM, et al. Gastric lavage in babies born through meconium stained amniotic fluid in prevention of early feed intolerance: a randomized controlled trial. J Neonatal Perinatal Med. 2018;11(4):393-7. Abstract

41. Gidaganti S, Faridi MM, Narang M, et al. Effect of gastric lavage on meconium aspiration syndrome and feed intolerance in vigorous infants born with meconium stained amniotic fluid: a randomized control trial. Indian Pediatr. 2018 Mar 15;55(3):206-10. Abstract

42. Hofmeyr GJ. Lawrie TA. Amnioinfusion for potential or suspected umbilical cord compression in labour. Cochrane Database Syst Rev. 2012 Jan 18;(1):CD000013.Full text  Abstract

43. Hofmeyr GJ, Xu H, Eke AC. Amnioinfusion for meconium-stained liquor in labour. Cochrane Database Syst Rev. 2014 Jan 23;(1):CD000014.Full text  Abstract

44. Phattraprayoon N, Tangamornsuksan W, Ungtrakul T. Outcomes of endotracheal suctioning in non-vigorous neonates born through meconium-stained amniotic fluid: a systematic review and meta-analysis. Arch Dis Child Fetal Neonatal Ed. 2021 Jan;106(1):31-8.Full text  Abstract

45. Nangia S, Thukral A, Chawla D. Tracheal suction at birth in non-vigorous neonates born through meconium-stained amniotic fluid. Cochrane Database Syst Rev. 2021 Jun 16;6(6):CD012671.Full text  Abstract

46. Trevisanuto D, Strand ML, Kawakami MD, et al. Tracheal suctioning of meconium at birth for non-vigorous infants: a systematic review and meta-analysis. Resuscitation. 2020 Apr;149:117-26. Abstract

47. Aziz K, Lee HC, Escobedo MB, et al. Part 5: neonatal resuscitation: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2020 Oct 20;142(16_suppl_2):S524-50.Full text

48. Benny PS, Malani S, Hoby MA, et al. Meconium aspiration: role of obstetric factors and suction. Aust N Z J Obstet Gynaecol. 1987 Feb;27(1):36-9. Abstract

49. Mandell E, Kinsella JP, Abman SH. Persistent pulmonary hypertension of the newborn. Pediatr Pulmonol. 2021 Mar;56(3):661-9. Abstract

50. Tybulewicz AT, Clegg SK, Fonfe G, et al. Preterm meconium staining of the amniotic fluid: associated findings and risk of adverse clinical outcome. Arch Dis Child Fetal Neonatal Ed. 2004 Jul;89(4):F328-30.Full text  Abstract

51. Downes JJ, Vidyasagar D, Boggs TR Jr, et al. Respiratory distress syndrome of newborn infants. I. New clinical scoring system (RDS score) with acid-base and blood-gas correlations. Clin Pediatr (Phila). 1970 Jun;9(6):325-31. Abstract

52. Lakshminrusimha S, Keszler M. Persistent pulmonary hypertension of the newborn. Neoreviews. 2015 Dec;16(12):e680-92.Full text  Abstract

53. American College of Obstetricians and Gynecologists. Committee opinion no 689: delivery of a newborn with meconium-stained amniotic fluid. Obstet Gynecol. 2017 Mar;129(3):e33-4.Full text  Abstract

54. Puopolo KM, Benitz WE, Zaoutis TE, et al. Management of neonates born at ≥35 0/7 weeks' gestation with suspected or proven early-onset bacterial sepsis. Pediatrics. 2018 Dec;142(6):e20182894.Full text  Abstract

55. Pandita A, Murki S, Oleti TP, et al. Effect of nasal continuous positive airway pressure on infants with meconium aspiration syndrome: a randomized clinical trial. JAMA Pediatr. 2018 Feb 1;172(2):161-5.Full text  Abstract

56. El Shahed AI, Dargaville P, Ohlsson A, et al. Surfactant for meconium aspiration syndrome in term and late preterm infants. Cochrane Database Syst Rev. 2014 Dec 14;(12):CD002054.Full text  Abstract

57. Abdelaal MA, Abushanab D, Al-Badriyeh D. Surfactant therapy for meconium aspiration syndrome in neonates: a systematic overview of systematic reviews and recent clinical trials. J Comp Eff Res. 2020 Jun;9(8):527-36. Abstract

58. Arayici S, Sari FN, Kadioglu Simsek G, et al. Lung lavage with dilute surfactant vs. bolus surfactant for meconium aspiration syndrome. J Trop Pediatr. 2019 Oct 1;65(5):491-7.Full text  Abstract

59. Dargaville PA, Copnell B, Mills JF, et al; lessMAS Trial Study Group. Randomized controlled trial of lung lavage with dilute surfactant for meconium aspiration syndrome. J Pediatr. 2011 Mar;158(3):383-9;e2.Full text  Abstract

60. Hahn S, Choi HJ, Soll R, et al. Lung lavage for meconium aspiration syndrome in newborn infants. Cochrane Database Syst Rev. 2013 Apr 30;(4):CD003486.Full text  Abstract

61. Jain A, Giesinger RE, Dakshinamurti S, et al. Care of the critically ill neonate with hypoxemic respiratory failure and acute pulmonary hypertension: framework for practice based on consensus opinion of neonatal hemodynamics working group. J Perinatol. 2022 Jan;42(1):3-13. Abstract

62. Osman A, Halling C, Crume M, et al. Meconium aspiration syndrome: a comprehensive review. J Perinatol. 2023 Oct;43(10):1211-21. Abstract

63. Kinsella JP, Truog WE, Walsh WF, et al. Randomized, multicenter trial of inhaled nitric oxide and high-frequency oscillatory ventilation in severe, persistent pulmonary hypertension of the newborn. J Pediatr. 1997 Jul;131(1 Pt 1):55-62. Abstract

64. Barrington KJ, Finer N, Pennaforte T, et al. Nitric oxide for respiratory failure in infants born at term or near term. Cochrane Database Syst Rev. 2017 Jan 5;(1):CD000399.Full text  Abstract

65. Radhakrishnan RS, Lally PA, Lally KP, et al. ECMO for meconium aspiration syndrome: support for relaxed entry criteria. ASAIO J. 2007 Jul-Aug;53(4):489-91. Abstract

66. Bartlett RH, Gazzaniga AB, Huxtable RF, et al. Extracorporeal circulation (ECMO) in neonatal respiratory failure. J Thorac Cardiovasc Surg. 1977 Dec;74(6):826-33. Abstract

67. Fox WW, Gewitz MH, Dinwiddie R, et al. Pulmonary hypertension in perinatal aspiration syndromes. Pediatrics. 1977 Feb;59(2):205-11. Abstract

68. Steinhorn RH. Nitric oxide and beyond: new insights and therapies for pulmonary hypertension. J Perinatol. 2008 Dec;28(suppl 3):S67-71.Full text  Abstract

69. Kelly LE, Ohlsson A, Shah PS. Sildenafil for pulmonary hypertension in neonates. Cochrane Database Syst Rev. 2017 Aug 4;(8):CD005494.Full text  Abstract

70. Yamada NK, Szyld E, Strand ML, et al. 2023 American Heart Association and American Academy of Pediatrics focused update on neonatal resuscitation: an update to the American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2024 Jan 2;149(1):e157-66.Full text  Abstract

71. Roggensack A, Jefferies AL, Farine D, et al. Management of meconium at birth. J Obstet Gynaecol Can. 2009 Apr;31(4):353-4. Abstract

72. Beligere N, Rao R. Neurodevelopmental outcome of infants with meconium aspiration syndrome: report of a study and literature review. J Perinatol. 2008 Dec;28(suppl 3):S93-101.Full text  Abstract

73. Macfarlane PI, Heaf DP. Pulmonary function in children after neonatal meconium aspiration syndrome. Arch Dis Child. 1988 Apr;63(4):368-72.Full text  Abstract

74. Rossi AC, Prefumo F. Antepartum and intrapartum risk factors for neonatal hypoxic-ischemic encephalopathy: a systematic review with meta-analysis. Curr Opin Obstet Gynecol. 2019 Dec;31(6):410-7. Abstract