Evaluation of breast mass

Last reviewed: 1 Apr 2025
Last updated: 11 Mar 2025

Summary

Differentials

Common

  • Fibroadenoma
  • Fibrocystic breast
  • Fat necrosis
  • Intraductal papilloma
  • Breast abscess
  • Invasive breast cancer
  • Ductal carcinoma in situ (DCIS)
Full details

Uncommon

  • Phyllodes tumor
  • Adenoma
  • Atypical ductal hyperplasia (ADH) and atypical lobular hyperplasia (ALH)
  • Radial scar
  • Lobular carcinoma in situ (LCIS)
Full details

Contributors

Authors

Marios-Konstantinos Tasoulis, MD, PhD

Consultant Breast Surgeon

Breast Surgery Unit

The Royal Marsden Hospital NHS Foundation Trust

London

UK

Disclosures

M-KT declares that he has no competing interests.

Samantha Muktar, MBBS, FRCS (Eng), MSc, BMedSci

Consultant Breast Surgeon

Breast Surgery Unit

London North West University Healthcare

London

UK

Disclosures

SM declares that she has no competing interests.

Acknowledgements

Dr Marios-Konstantinos Tasoulis would like to gratefully acknowledge Professor Anees Chagpar and Dr Matthew Bower, previous contributors to this topic.

Disclosures

AC and MB declare that they have no competing interests.

Peer reviewers

William Dooley, MD, FACS

Director of Surgical Oncology

Department of Surgery

University of Oklahoma

G. Rainey Williams Chair in Surgical Breast Oncology

OU Breast Institute

Oklahoma City

OK

Disclosures

WD declares that he has no competing interests.

Jesus Solier Insuasty Enriquez, MD

Oncology Unit

Hospital Universitario Ramon Gonzalez Valencia

Bucaramanga

Colombia

Disclosures

JE declares that he has no competing interests.

Justin Stebbing, MA, MRCP, MRCPath, PhD

Consultant Medical Oncologist/Senior Lecturer

Department of Medical Oncology

Imperial College/Imperial Healthcare NHS Trust

Charing Cross Hospital

London

UK

Disclosures

JS declares that he has no competing interests.

References

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Key articles

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: breast cancer screening and diagnosis [internet publication].Full text

American College of Radiology. ACR appropriateness criteria: palpable breast masses. 2022 [internet publication].Full text

American College of Radiology. ACR practice parameter for the performance of a diagnostic breast ultrasound examination. 2021 [internet publication].Full text

American College of Radiology. ACR practice parameter for the performance of ultrasound-guided percutaneous breast interventional procedures. 2021 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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