Periodic limb movement disorder

References

Key articles

Garcia-Borreguero D, Ferini-Strambi L, Kohnen R, et al. European guidelines on management of restless legs syndrome: report of a joint task force by the European Federation of Neurological Societies, the European Neurological Society and the European Sleep Research Society. Eur J Neurol. 2012;19:1385-1396. Abstract

Ferri R, Fulda S, Allen RP, et al. World Association of Sleep Medicine (WASM) 2016 standards for recording and scoring leg movements in polysomnograms developed by a joint task force from the International and the European Restless Legs Syndrome Study Groups (IRLSSG and EURLSSG). Sleep Med. 2016 Oct;26:86-95. Abstract

Aurora RN, Kristo DA, Bista SR, et al. The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine Clinical Practice Guideline. Sleep. 2012 Aug 1;35(8):1039-62.Full text  Abstract

Reference articles

1. American Academy of Sleep Medicine. The AASM international classification of sleep disorders - third edition, text revision (ICSD-3-TR). 2023 [internet publication].Full text

2. Garcia-Borreguero D, Ferini-Strambi L, Kohnen R, et al. European guidelines on management of restless legs syndrome: report of a joint task force by the European Federation of Neurological Societies, the European Neurological Society and the European Sleep Research Society. Eur J Neurol. 2012;19:1385-1396. Abstract

3. Ferri R, Fulda S, Allen RP, et al. World Association of Sleep Medicine (WASM) 2016 standards for recording and scoring leg movements in polysomnograms developed by a joint task force from the International and the European Restless Legs Syndrome Study Groups (IRLSSG and EURLSSG). Sleep Med. 2016 Oct;26:86-95. Abstract

4. Hornyak M, Feige B, Reimann D, et al. Periodic leg movements in sleep and periodic limb movement disorder: prevalence, clinical significance and treatment. Sleep Med Rev. 2006;10:169-177. Abstract

5. Aurora RN, Kristo DA, Bista SR, et al. The treatment of restless legs syndrome and periodic limb movement disorder in adults-an update for 2012: practice parameters with an evidence-based systematic review and meta-analyses: an American Academy of Sleep Medicine Clinical Practice Guideline. Sleep. 2012 Aug 1;35(8):1039-62.Full text  Abstract

6. Montplaisir J, Boucher S, Poirier G, et al. Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: a study of 133 patients diagnosed with new standard criteria. Mov Disord. 1997;12:61-65. Abstract

7. Rijsman RM, Stam CJ, de Weerd AW. Abnormal H-reflexes in periodic limb movement disorder: impact on understanding the pathophysiology of the disorder. Clin Neurophysiol. 2005;116:204-210. Abstract

8. Scofield H, Roth T, Drake C. Periodic limb movements during sleep: population prevalence, clinical correlates, and racial differences. J Sleep. 2008;31:1221-1227.Full text  Abstract

9. Picchietti DL, Walters AS. Moderate to severe periodic limb movement disorder in childhood and adolescence. Sleep. 1999;22:297-300. Abstract

10. Chervin RD, Archbold KH, Dillon JE, et al. Associations between symptoms of inattention, hyperactivity, restless legs, and periodic leg movements. Sleep. 2002;25:213-218. Abstract

11. Gehrman P, Stepnowsky C, Cohen-Zion M, et al. Long-term follow-up of periodic limb movements in sleep in older adults. Sleep. 2002;25:340-343. Abstract

12. Ancoli-Israel S, Kripke DF, Klauber MR, et al. Periodic limb movements in sleep in community-dwelling elderly. Sleep. 1991;14:496-500. Abstract

13. Carrier J, Frenette S, Montplaisir J, et al. Effects of periodic leg movements during sleep in middle-aged subjects without sleep complaints. Mov Disord. 2005;20:1127-1132. Abstract

14. Hornyak M, Trenkwalder C. Restless legs syndrome and periodic limb movement disorder in the elderly. J Psychosom Res. 2004;56:543-548. Abstract

15. Haba-Rubio J, Marti-Soler H, Marques-Vidal P, et al. Prevalence and determinants of periodic limb movements in the general population. Ann Neurol. 2016 Mar;79(3):464-74. Abstract

16. Ohayon MM, Roth T. Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. J Psychosom Res. 2002;53:547-554. Abstract

17. Leary EB, Moore HE 4th, Schneider LD, et al. Periodic limb movements in sleep: Prevalence and associated sleepiness in the Wisconsin Sleep Cohort. Clin Neurophysiol. 2018 Nov;129(11):2306-2314.Full text  Abstract

18. Vetrugno R, Provini F, Plazzi G, et al. Propriospinal myoclonus: a motor phenomenon found in restless legs syndrome different from periodic limb movements during sleep. Mov Disord. 2005; 20:1323-1329. Abstract

19. Lee MS, Choi YC, Lee SH, et al. Sleep-related periodic leg movements associated with spinal cord lesions. Mov Disord. 1996;11:719-722. Abstract

20. Lee MS, Lyoo CH, Kim WC, et al. Periodic bursts of rhythmic dyskinesia associated with spinal anesthesia. Mov Disord. 1997;12:816-817. Abstract

21. Bucher SF, Seeleos KC, Oertel WH, et al. Cerebral generators involved in the pathogenesis of the restless legs syndrome. Ann Neurol. 1997;41:639-645. Abstract

22. Bara-Jimenez W, Aksu M, Graham B, et al. Periodic limb movements in sleep: state-dependent excitability of the spinal flexor reflex. Neurology. 2000;54:1609-1616. Abstract

23. Allen R. Dopamine and iron in the pathophysiology of restless legs syndrome (RLS). Sleep Med. 2004;5:385-391. Abstract

24. Clemens S, Rye D, Hochman S. Restless legs syndrome: revisiting the dopamine hypothesis from the spinal cord perspective. Neurology. 2006;67:125-130. Abstract

25. Cervenka S, Palhagen SE, Comley RA, et al. Support for dopaminergic hypoactivity in restless legs syndrome: a PET study on D2-receptor binding. Brain. 2006;129:2017-2028.Full text  Abstract

26. Szentkirályi A, Stefani A, Hackner H, et al. Prevalence and associated risk factors of periodic limb movement in sleep in two German population-based studies. Sleep. 2019 Mar 1;42(3):.Full text  Abstract

27. American Academy of Sleep Medicine. The AASM manual for the scoring of sleep and associated events. 2023 [internet publication].Full text

28. Wang J, O'Reilly B, Venkataraman R, et al. Efficacy of oral iron in patients with restless legs syndrome and a low-normal ferritin: a randomized, double-blind, placebo-controlled study. Sleep Med. 2009;10:973-975. Abstract

29. Sforza E, Johannes M, Claudio B. The PAM-RL ambulatory device for detection of periodic leg movements: a validation study. Sleep Med. 2005;6:407-413. Abstract

30. Smith MT, McCrae CS, Cheung J, et al. Use of actigraphy for the evaluation of sleep disorders and circadian rhythm sleep-wake disorders: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2018 Jul 15;14(7):1231-7.Full text  Abstract

31. Kunz D, Bes F. Exogenous melatonin in periodic limb movement disorder: an open clinical trial and a hypothesis. Sleep. 2001;24:183-187. Abstract

32. Nofzinger E, Fasiczka A, Berman S, et al. Bupropion SR reduces periodic limb movements associated with arousals from sleep in depressed patients with periodic limb movement disorder. J Clin Psychiatry. 2000;61:858-862. Abstract

33. Wu MN, Tseng PT, Chen TY, et al. The efficacy and tolerability of rotigotine on patients with periodic limb movement in sleep: a systematic review and meta-analysis. PLoS One. 2018;13(4):e0195473.Full text  Abstract

34. Grewal M, Hawa R, Shapiro C. Treatment of periodic limb movements in sleep with selegiline HCl. Mov Disord. 2002;17:398-401. Abstract

35. Ehrenberg BL, Eisensehr I, Corbett KE, et al. Valproate for sleep consolidation in periodic limb movement disorder. J Clin Psychoparmacol. 2000;20:574-578. Abstract

36. Hornyak M, Voderholzer U, Hohagen F, et al. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501-505. Abstract

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