Molar pregnancies

Chromosomally abnormal pregnancies that have the potential to become malignant.

Higher possibility of gestational trophoblastic disease (GTD) for women less than 20 years of age or over 35 years of age, and in those who have experienced GTD in a previous pregnancy.

Most common presenting symptom is vaginal bleeding.

Suction dilation and evacuation (D&E) or hysterectomy are the preferred treatments.

The risk of post-molar neoplasm is almost 20% for those with complete molar pregnancy.

Rate of cure for post-molar gestational trophoblastic neoplasia exceeds 95%, often with preservation of fertility.

Hydatidiform moles are chromosomally abnormal pregnancies that have the potential to become malignant (gestational trophoblastic neoplasia). Gestational trophoblastic disease includes tumours of fetal tissues, including hydatidiform moles, arising from placental trophoblasts. Syncytiotrophoblasts secrete human chorionic gonadotrophin (hCG) and, therefore, this hormonal product is used as a tumour marker for the disease.