Salicylate poisoning

Palmer BF, Clegg DJ. Salicylate toxicity. N Engl J Med. 2020 Jun 25;382(26):2544-55. Abstract

Chyka PA, Erdman AR, Christianson G, et al. Salicylate poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol (Phila). 2007;45(2):95-131.Full text  Abstract

American College of Medical Toxicology. Guidance document: management priorities in salicylate toxicity. J Med Toxicol. 2015 Mar;11(1):149-52.Full text

Dargan PI, Wallace CI, Jones AL. An evidence based flowchart to guide the management of acute salicylate (aspirin) overdose. Emerg Med J. 2002 May;19(3):206-9.Full text  Abstract

1. Palmer BF, Clegg DJ. Salicylate toxicity. N Engl J Med. 2020 Jun 25;382(26):2544-55. Abstract

2. Chyka PA, Erdman AR, Christianson G, et al. Salicylate poisoning: an evidence-based consensus guideline for out-of-hospital management. Clin Toxicol (Phila). 2007;45(2):95-131.Full text  Abstract

3. Gummin DD, Mowry JB, Beuhler MC, et al. 2021 Annual report of the National Poison Data System(©) (NPDS) from America's Poison Centers: 39th annual report. Clin Toxicol (Phila). 2022 Dec;60(12):1381-643.Full text  Abstract

4. Srisuma S, Cao D, Kleinschmidt K, et al. Missed opportunities?: an evaluation of potentially preventable poisoning deaths. Clin Toxicol (Phila). 2016 Mar 21;54(5):441-6. Abstract

5. Hawton K, Simkin S, Deeks J, et al. UK legislation on analgesic packs: before and after study of long term effect on poisonings. BMJ. 2004 Nov 6;329(7474):1076.Full text  Abstract

6. Johnson PN, Welch DW. Methyl salicylate/aspirin (salicylate) equivalence: who do you trust? Vet Hum Toxicol. 1984 Aug;26(4):317-8.

7. Gabow PA, Anderson RJ, Potts DE, et al. Acid-base disturbances in the salicylate-intoxicated adult. Arch Intern Med. 1978 Oct;138(10):1481-4. Abstract

8. Reed JR, Palmisano PA. Central nervous system salicylate. Clin Toxicol. 1975;8(6):623-31. Abstract

9. Jacob J, Lavonas EJ. Falsely normal anion gap in severe salicylate poisoning caused by laboratory interference. Ann Emerg Med. 2011 Sep;58(3):280-1 Abstract

10. Rich RR, Johnson JS. Salicylate hepatotoxicity in patients with juvenile rheumatoid arthritis. Arthritis Rheum. 1973 Jan-Feb;16(1):1-9. Abstract

11. Wolfe JD, Metzger AL, Goldstein RC. Aspirin hepatitis. Ann Intern Med. 1974 Jan;80(1):74-6. Abstract

12. Matthay MA, Arabi Y, Arroliga AC, et al. A new global definition of acute respiratory distress syndrome. Am J Respir Crit Care Med. 2024 Jan 1;209(1):37-47.Full text  Abstract

13. American College of Medical Toxicology. Guidance document: management priorities in salicylate toxicity. J Med Toxicol. 2015 Mar;11(1):149-52.Full text

14. Kent K, Ganetsky M, Cohen J, et al. Non-fatal ventricular dysrhythmias associated with severe salicylate toxicity. Clin Toxicol (Phila). 2008 Apr;46(4):297-9. Abstract

15. Meaden CW, Calello DP. Bismuth subsalicylate poisoning. N Engl J Med. 2022 Dec 1;387(22):2074.

16. Sainsbury SJ. Fatal salicylate toxicity from bismuth subsalicylate. West J Med. 1991 Dec;155(6):637-9.Full text

17. Halani S, Wu PE. Salicylate toxicity from chronic bismuth subsalicylate use. BMJ Case Rep. 2020 Nov 30;13(11):e236929.Full text  Abstract

18. Dargan PI, Wallace CI, Jones AL. An evidence based flowchart to guide the management of acute salicylate (aspirin) overdose. Emerg Med J. 2002 May;19(3):206-9.Full text  Abstract

19. Fahlen M, Duarte AG. Gait disturbance, confusion, and coma in a 93-year-old blind woman. Chest. 2001 Jul;120(1):295-7.Full text  Abstract

20. Lynd LD, Richardson KJ, Purssell RA, et al. An evaluation of the osmole gap as a screening test for toxic alcohol poisoning. BMC Emerg Med. 2008 Apr 28;8:5.Full text  Abstract

21. Done AK. Aspirin overdose: incidence, diagnosis and management. Pediatrics. 1978 Nov;62(5 Pt 2 Suppl):890-7.

22. Dugandzic RM, Tierney MG, Dickinson GE, et al. Evaluation of the validity of the Done nomogram in the management of acute salicylate intoxication. Ann Emerg Med. 1989 Nov;18(11):1186-90. Abstract

23. The Royal Children's Hospital Melbourne. Salicylates poisoning. June 2017 [internet publication].Full text

24. Mégarbane B, Oberlin M, Alvarez JC, et al. Management of pharmaceutical and recreational drug poisoning. Ann Intensive Care. 2020 Nov 23;10(1):157.Full text  Abstract

25. Barone, J, Raia J, Huang YC. Evaluation of the effects of multiple-dose activated charcoal on the absorption of orally administered salicylate in a simulated toxic ingestion model. Ann Emerg Med. 1988 Jan;17(1):34-7. Abstract

26. Neuvonen PJ, Elfving SM, Elonen E. Reduction of absorption of digoxin, phenytoin, and aspirin by activated charcoal in man. Eur J Clin Pharmacol. 1978 May 31;13(3):213-8. Abstract

27. Oh MS, Halperin ML. Toxin-induced metabolic acidosis. In: Gennari FJ, Adrogue HJ, Galla JH, et al, eds. Acid-base disorders and their treatment. Boca Raton, FL: Taylor & Francis; 2005:383-416.

28. Curry SC, Pizon AF, Riley BD, et al. Effect of intravenous albumin infusion on brain salicylate concentration. Acad Emerg Med. 2007 Jun;14(6):508-14.Full text  Abstract

29. Davison C. Salicylate metabolism in man. Ann NY Acad Sci. 1971 Jul 6;179:249-68. Abstract

30. American Academy of Clinical Toxicology, European Association of Poisons Centres and Clinical Toxicologists. Position paper: single-dose activated charcoal. Clin Toxicol (Phila). 2005;43(2):61-87.Full text  Abstract

31. Proudfoot AT, Krenzelok EP, Vale JA. Position paper on urine alkalinization. J Toxicol Clin Toxicol. 2004;42(1):1-26.Full text  Abstract

32. Shively RM, Hoffman RS, Manini AF. Acute salicylate poisoning: risk factors for severe outcome. Clin Toxicol (Phila). 2017 Mar;55(3):175-80.Full text  Abstract

33. Done AK. Salicylate intoxication: significance of measurements of salicylate in blood in cases of acute ingestion. Pediatrics. 1960 Nov;26:800-7. Abstract