The prevalence of precocious puberty is difficult to estimate but has been reported at 1 in 5000 children. Gonadotrophin-dependent precocious puberty or central precocious puberty affects girls 10 times more commonly than boys. This may be because activation of the hypothalamo-pituitary-gonadal axis requires a lower dose of gonadotrophin-releasing hormone (GnRH) in girls. In the US, the number of girls diagnosed with precocious puberty is rising but there are no reliable data on the incidence. One study showed that 10% to 23% of 7-year old girls (depending on race and ethnicity) have breast development, but the proportion who have the type of progressive precocious puberty that might require treatment is likely much lower.
BMJ Best Practice is an evidence-based point of care tool for healthcare practitioners.
To continue reading and access all of BMJ Best Practice's pages you'll need to log in or start a free trial.
You can access through your institution if your hospital, university, trust or other institution provides access to BMJ Best Practice through either OpenAthens or Shibboleth.
Use of this content is subject to our disclaimer