ASDs occur in 1 of 1500 live births. Secundum-type ASDs constitute 6% to 10% of congenital heart defects and have a 2:1 female-to-male predominance. Secundum defects account for 75% of ASDs. The other types of ASDs occur far less frequently: ostium primum (15% of ASDs), sinus venosus (5% of ASDs), and unroofed coronary sinus defects (1% of ASDs). ASDs can also occur in conjunction with more significant congenital heart defects.
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